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Ahumada C, Bahamondes C, Cerda CA, Silva RA, Cruz G, Moya PR, Sotomayor-Zárate R, Renard GM. (2017) Amphetamine treatment affects the extra-hypothalamic vasopressinergic system in a sex- and nucleus-dependent manner. J Neuroendocrinol. 29(4). doi: 10.1111/jne.12465
Alvarez O, Carmona E, Latorre R & Gonzalez C. (2018) A Glimpse into the Permeation Pathway of the Voltage-Dependent Proton Channel (Hv1). Comments on CrossTalk 33: Proton permeation through HV1 requires/does not require transient protonation of a conserved aspartate in the S1 transmembrane helix. Journal of Physiology. https://physoc.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1113%2FJP274495&attachmentId=2213602375
Alvarez O and Latorre R. (2017) The enduring legacy of the “constant-field equation” in membrane ion transport J Gen Physiol. 149(10):911-920. doi: 10.1085/jgp.201711839
Ardiles AO, Grabrucker AM, Scholl FG, Rudenko G, Borsello T. (2017). Molecular and Cellular Mechanisms of Synaptopathies. Neural Plast. 2017:2643943. doi: 10.1155/2017/2643943
Asuaje A, Smaldini P, Martín P, Enrique N, Orlowski A, Aiello EA, Gonzalez León C, Docena G, Milesi V. (2017) The inhibition of voltage-gated H+ channel (HVCN1) induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis. Pflugers Arch. 469(2):251-261. doi: 10.1007/s00424-016-1928-
Berna-Erro A, Izquierdo-Serra M, Sepúlveda RV, Rubio-Moscardo F, Doñate-Macián P, Serra SA, Carrillo-Garcia J, Perálvarez-Marín A, Gonzalez-Nilo F, Fernández-Fernández JM, Valverde MA (2017) Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel. Sci Rep. 7(1):10522. doi: 10.1038/s41598-017-11274-1
Calbiague VM, Olivares J, Olivares E, Schmachtenberg O (2017) The Chilean Recluse Spider (Araneae: Sicariidae) Displays Behavioral Responses to Conspecific Odors, but Not to Several General Odorants. J Med Entomol. 54(5):1435-1439. doi: 10.1093/jme/tjx101
Cárdenas AM, Fernández-Olivares P, Diaz-Franulic I, González-Jamett AM, Shimahara T, Segura-Aguilar J, Caviedes R, Caviedes P. (2017) Knockdown of Myo-Inositol Transporter SMIT1 Normalizes Cholinergic and Glutamatergic Function in an Immortalized Cell Line Established from the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Human Trisomy 21 (Down Syndrome). Neurotox Res. 32(4):614-623. doi: 10.1007/s12640-017-9775-0
Castillo K, Diaz-Franulic I, Canan J, Gonzalez-Nilo F and Latorre R. (2017) Thermally-activated TRP channels: Molecular sensors for temperature detection. Physical Biology. 15(2):021001. doi: 10.1088/1478-3975/aa9a6f.
Castillo K, Valenzuela V, Oñate M and Hetz C. 2016. A molecular reporter for monitoring autophagic flux in nervous system in vivo. Methods in Enzymology 588:109-131. doi: 10.1016/bs.mie.2016.09.077
Castro-Severyn J, Remonsellez F, Valenzuela SL, Salinas C, Fortt J, Aguilar P, Pardo-Esté C, Dorador C, Quatrini R, Molina F, Aguayo D, Castro-Nallar E, Saavedra CP. (2017) Comparative Genomics Analysis of a New Exiguobacterium Strain from Salar de Huasco Reveals a Repertoire of Stress-Related Genes and Arsenic Resistance. Front Microbiol. 8:456. doi: 10.3389/fmicb.2017.00456.
Charvériat M, Naus CC, Leybaert L, Sáez JC, Giaume C. (2017) Connexin-Dependent Neuroglial Networking as a New Therapeutic Target. Front Cell Neurosci. 11:174. doi: 10.3389/fncel.2017.00174. eCollection 2017. Review.
Couve E, Lovera M, Suzuki K, Schmachtenberg O. (2017) Schwann cell phenotypes in the aging human dental pulp. J Dental Res. 97(3):347-355. doi: 10.1177/002203451773396
Escobar AP (2017) The Role of Kappa Opioid Receptors in Glutamate Input Selection in the Ventral Striatum. J Neurosci. 2017 Nov 15;37(46):11072-11073 Doi: 10.1523/JNEUROSCI.2381-17.2017
Espinosa N, Alonso A, Morales C, Espinosa P, Chávez AE, Fuentealba P. (2017) Basal Forebrain Gating by Somatostatin Neurons Drives Prefrontal Cortical Activity. Cereb cortex. 29(1):42-53. doi: 10.1093/cercor/bhx302
Gajardo-Gómez R, Labra VC, Maturana CJ, Shoji KF, Santibañez CA, Sáez JC, Giaume C, Orellana JA. (2016) Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism. Glia. 65(1):122-137. doi: 10.1002/glia.23080.
Giaume C, Sáez JC, Song W, Leybaert L, Naus CC. (2017) Connexins and pannexins in Alzheimer’s disease. Neurosci Lett. 695:100-105 doi: 10.1016/j.neulet.2017.09.006
González A, Herrera G, Ugarte G, Restrepo C, Piña R, Pertusa M, Orio P, Madrid R. (2017) IKD Current in Cold Transduction and Damage-Triggered Cold Hypersensitivity. Adv Exp Med Biol. 2017;1015:265-277. doi: 10.1007/978-3-319-62817-2_14.
González A, Ugarte G, Restrepo C, Herrera G, Piña R, Gómez-Sánchez JA, Pertusa M, Orio P, Madrid R. (2017) Role of the excitability brake potassium current IKD in cold allodynia induced by chronic peripheral nerve injury. J Neurosci. 37 (12) 3109-3126; doi: 10.1523/JNEUROSCI.3553-16.2017.
González LF, Henríquez-Belmar F, Delgado-Acevedo C, Cisternas-Olmedo M, Arriagada G, Sotomayor-Zárate R, Murphy DL, Moya PR. (2017) Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice. Biol Res. 50(1):29. doi: 10.1186/s40659-017-0138-3.
González-Jamett AM , Guerra MJ , Olivares MJ , Haro-Acuña V , Baéz-Matus X , Vásquez-Navarrete J, Momboisse F , Martinez-Quiles N, Cárdenas AM. (2017). The F-Actin Binding Protein Cortactin Regulates the Dynamics of the Exocytotic Fusion Pore through its SH3 Domain. Front. Cell. Neurosci., doi: 10.3389 /fnc el.2017.00130
Gutierrez-Maldonado SE, Garate JA, Retamal MJ, Cisternas MA, Volkmann UG, Pérez-Acle T(2017) Accessing the structural and thermodynamic properties of ultra-thin layers of C32 adsorbed on a SiO2 surface. Chemical Physics Letters. 674: 64–70. doi: 10.1016/j.cplett.2017.01.065
Hashimotodani Y, Nasrallah K, Jensen KR, Chávez AE, Carrera D, Castillo PE. (2017) LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance. Neuron. 95(4):928-943.e3. doi: 10.1016/j.neuron.2017.07.028.
Latorre R, Castillo K, Carrasquel-Ursulaez W, Sepulveda RV, Gonzalez-Nilo F, Gonzalez C and Alvarez O. 2016. Molecular determinants of BK channel functional diversity and functioning. Physiological Reviews, 97(1):39-87 doi:10.1152/physrev.00001.2016
Manzanares D, Araya-Durán I, Gallego-Yerga L, Játiva P, Márquez-Miranda V, Canan J, Jiménez Blanco JL, Mellet CO, Gonzalez-Nilo FD, García Fernández JM, Ceña V. (2017) Molecular determinants for cyclo-oligosaccharide-based nanoparticle-mediated effective siRNA transfection. Nanomedicine (Lond). 12(13):1607-1621. doi: 10.2217/nnm-2017-0123.
Márquez-Miranda V, Abrigo J, Rivera JC, Araya-Durán I, Aravena J, Simon F, Pacheco N, Gonzalez-Nilo FD, Cabello-Verrugio C. (2017) The complex of PAMAM-OH dendrimer with Angiotensin (1-7) prevented the disuse-induced skeletal muscle atrophy in mice. Int J Nanomedicine. 12:1985-1999. doi: 10.2147/IJN.S125521.
Martin AJ, Contreras-Riquelme S, Dominguez C, Pérez-Acle T. (2017) LoTo: a graphlet based method for the comparison of local topology between gene regulatory networks. PeerJ. 5:e3052. doi: 10.7717/peerj.3052.
Maturana CJ, Aguirre A, Sáez JC. (2016) High glucocorticoid levels during gestation activate the inflammasome in hippocampal oligodendrocytes of the offspring. Dev Neurobiol. 77(5):625-642. doi: 10.1002/dneu.22409
Muñoz PA, Márquez SL, Gonzalez-Nilo FD, Márquez-Miranda V, Blamey JM. (2017) Structure and application of antifreeze proteins from Antarctic bacteria. Microb Cell Fact. 16(1):138. doi: 10.1186/s12934-017-0737-2
Palacios AG, Escobar M J. and Céspedes E. (2017) Missing colors: The enactivist approach to perception. Constructivist Foundations. 13(1): 117–125. http://constructivist.info/13/1/117.
Palacios AG, Escobar MJ, Céspedes E (2017). Authors’ Response: Is a Weak Notion of Representation not Compatible with a Contextualist and Enactivist Account of Perception?. Constructivist Foundations, 13 (1): 135-140
Palominos MF, Verdugo L, Gabaldon C, Pollak B, Ortíz-Severín J, Varas MA, Chávez FP, Calixto A. (2017) Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans. MBio. 2017 Oct 10;8(5). pii: e01234-17. doi: 10.1128/mBio.01234-17.
Peñaloza JP, Márquez-Miranda V, Cabaña-Brunod M, Reyes-Ramírez R, Llancalahuen FM, Vilos C, Maldonado-Biermann F, Velásquez LA, Fuentes JA, Gonzalez-Nilo FD, Rodríguez-Díaz M, Otero C. (2017) Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines. J Nanobiotechnology. 15(1):1. doi: 10.1186/s12951-016-0241-6.
Pérez-Acle T, Fuenzalida I, Martin AJM, Santibañez R, Avaria R, Bernardin A, Bustos AM, Garrido D, Jonathan Dushoff, Liu JH. (2017) Stochastic simulation of multiscale complex systems with PISKaS: A rule-based approach. Biochem Biophys Res Commun. 498(2):342-351. doi: 10.1016/j.bbrc.2017.11.138
Pinto BI, Pupo A, García IE, Mena-Ulecia K, Martínez AD, Latorre R, Gonzalez C. (2017) Calcium binding and voltage gating in Cx46 hemichannels. Sci Rep. 7(1):15851. doi: 10.1038/s41598-017-15975-5
Plotkin LI, Davis HM, Cisterna BA, Sáez JC. (2017) Connexins and Pannexins in Bone and Skeletal Muscle. Curr Osteoporos Rep. 15(4):326-334. doi: 10.1007/s11914-017-0374-z. Review
Puebla C, Retamal MA, Acuña R, Sáez JC. (2017) Regulation of Connexin-Based Channels by Fatty Acids. Front Physiol. 8:11. doi: 10.3389/fphys.2017.00011. Review.
Rubat S, Varas I, Sepúlveda R, Almonacid D,Gonzalez-Nilo F, Agosin E (2017) Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase. FEMS Yeast Res. 17(4). doi: 10.1093/femsyr/fox032.
Sáez JC. (2017) Unravelling a novel mechanism for the up-regulation of connexin43 gap junctions between cells derived from the blood-brain barrier. J Physiol. 595(8):2411-2412. doi: 10.1113/JP274027
Sáez PJ, Vargas P, Shoji KF, Harcha PA, Lennon-Duménil AM, Sáez JC (2017) ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X7 receptors. Sci Signal. 10(506). pii: eaah7107. doi: 10.1126/scisignal.aah710
Salazar J, Alarcón M, Huerta J, Navarro B, Aguayo D. (2017) Phosphoethanolamine addition to the Heptose I of the Lipopolysaccharide modifies the inner core structure and has an impact on the binding of Polymyxin B to the Escherichia coli outer membrane. Arch Biochem Biophys. 620:28-34. doi: 10.1016/j.abb.2017.03.008
Sampogna-Mireles D, Araya-Durán ID, Márquez-Miranda V, Valencia-Gallegos JA, Gonzalez-Nilo FD (2017) Structural analysis of binding functionality of folic acid-PEG dendrimers against folate receptor. J Mol Graph Model. 72:201-208. doi:10.1016/j.jmgm.2017.01.004.
Selcho M, Millán C, Palacios-Muñoz A, Ruf F, Ubillo L, Chen J, Bergmann G, Ito C, Silva V, Wegener C, Ewer J. (2017) Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila. Nat Commun. 8:15563. doi: 10.1038/ncomms15563.
Vargas AA, Cisterna BA, Saavedra-Leiva F, Urrutia C, Cea LA, Vielma AH, Gutierrez-Maldonado SE, Martin AJ, Pareja-Barrueto C, Escalona Y,Schmachtenberg O, Lagos CF, Pérez-Acle T, Sáez JC. (2017) On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells. Front Physiol. 8:38. doi: 10.3389/fphys.2017.00038.
Vega-Zuniga T, Medina FS, Marín G, Letelier JC, Palacios AG, Němec P, Schleich CE, Mpodozis J. (2017) Selective binocular vision loss in two subterranean caviomorph rodents: Spalacopus cyanus and Ctenomys talarum. Sci Rep. 7:41704. doi: 10.1038/srep41704.
Villanelo F, Escalona Y, Pareja-Barrueto C, Garate JA, Skerrett IM, Pérez-Acle T (2017) Accessing gap-junction channel structure-function relationships through molecular modeling and simulations. .BMC Cell Biol. 18(Suppl 1):5. doi: 10.1186/s12860-016-0121-9. Review.
Wongsamitkul N, Maldifassi MC, Simeone X, Baur R, Ernst M, Sigel E (2017) α subunits in GABAA receptors are dispensable for GABA and diazepam action. Sci Rep. 7(1):15498. doi: 10.1038/s41598-017-15628-7.
Xu K., Maidana JP, Caviedes M, Quero D, Aguirre P and Orio P. (2017). Hyperpolarization-activated current induces period-doubling cascades and chaos in a cold thermoreceptor model. Front Comp Neurosci. 11:12. doi: 10.3389/fncom.2017.00012. eCollection 2017
Yi C, Ezan P, Fernández P, Schmitt J, Sáez JC, Giaume C, Koulakoff A. (2017) Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer’s disease. Glia. 65(10):1607-1625. doi: 10.1002/glia.23182
Zhong G, Akoum N, Appadurai DA, Hayrapetyan V, Ahmed O,Martínez AD, Beyer EC, Moreno AP. (2017) Mono-Heteromeric Configurations of Gap Junction Channels Formed by Connexin43 and Connexin45 Reduce Unitary Conductance and Determine both Voltage Gating and Metabolic Flux Asymmetry. Front Physiol. 8:346. doi: 10.3389/fphys.2017.00346.
Acevedo W, Gonzalez-Nilo F, Agosin E. (2016) Docking and Molecular Dynamics of Steviol Glycoside-Human Bitter Receptor Interactions. J Agric Food Chem. 64(40):7585-7596
Aliaga C, Bravo-Moraga F, Gonzalez-Nilo D, Márquez S, Lühr S, Mena G, Rezende MC. (2016) Location of TEMPO derivatives in micelles: subtle effect of the probe orientation. Food Chem. 192:395-401
Aspé-Sánchez M, Moreno M, Rivera MI, Rossi A and Ewer J. (2016) Oxytocin and vasopressin receptor gene polymorphisms: role in social and psychiatric traits Frontiers in Neuroscience 28;9:510. doi: 10.3389/fnins.2015.00510
Boetsch C, Aguayo-Villegas DR, Gonzalez-Nilo FD, Lisa ÁT, Beassoni PR. (2016) Putative binding mode of Escherichia coli exopolyphosphatase and polyphosphates based on a hybrid in silico/biochemical approach. Arch Biochem Biophys. 606:64-72. doi: 10.1016/j.abb.2016.07.005
Calfún C, Domínguez C, Pérez-Acle T, Whitlock KE. (2016) Changes in Olfactory Receptor Expression Are Correlated With Odor Exposure During Early Development in the zebrafish (Danio rerio). Chem Senses. 1861(5):439-48
Cárdenas AM, González-Jamett AM, Cea LA, Bevilacqua JA, Caviedes P. (2016) Dysferlin function in skeletal muscle: Possible pathological mechanisms and therapeutical targets in dysferlinopathies. Exp Neurol. Exp Neurol. 283(Pt A):246-254. doi: 10.1016/j.expneurol.2016.06.026
Cárdenas AM, Marengo F. (2016) How the stimulus defines the dynamics of vesicle pool recruitment, fusion mode and vesicle recycling in neuroendocrine cells. J Neurochem. 137(6):867-79. doi: 10.1111/jnc.13565
Castillo JP, Sánchez-Rodríguez JE, Clark Hyde H, Zaelzer CA, Aguayo D, Sepúlveda R, Luk LYP, Kent S, Gonzalez-Nilo F, Bezanilla F, andLatorre R. (2016) β1 Subunit-Induced Structural Rearrangements of the Ca2+- and Voltage-Activated (BK) Channel. Proc. Natl Acad Sci (USA). 113(23):E3231-9
Cea LA, Balboa E, Puebla C, Vargas AA, Cisterna BA, Escamilla R, Regueira T, Sáez JC. (2016) Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels. Biochim Biophys Acta. 1862(10):1891-9. doi: 10.1016/j.bbadis.2016.07.003
Cea LA, Bevilacqua JA, Arriagada C,Cárdenas AM, Bigot A, Mouly V, Sáez JC, Caviedes P. (2016) The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes. BMC Cell Biol. 17 Suppl 1:15. doi: 10.1186/s12860-016-0096-6.
Cea LA, Puebla C, Cisterna BA, Escamilla R, Vargas AA, Frank M, Martínez-Montero P, Prior C, Molano J, Esteban-Rodríguez I, Pascual I, Gallano P, Lorenzo G, Pian H, Barrio LC, Willecke K, Sáez JC. (2016) Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis. Cell Mol Life Sci. 73(13):2583-99. doi: 10.1007/s00018-016-2132-2
Chávez Andrés E. (2016) ¿Cómo afecta el color al comportamiento?: Una mirada a la visón ultravioleta en mamíferos. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 21-24.
Chetty S, Bhakat S, Martin AJ, Soliman ME. (2016) Multi-drug resistance profile of PR20 HIV-1 protease is attributed to distorted conformational and drug binding landscape: molecular dynamics insights. J Biomol Struct Dyn. 34(1):135-51.
Cisterna BA, Vargas AA, Puebla C, Sáez JC. (2016) Connexin hemichannels explain the ionic imbalance and lead to atrophy in denervated skeletal muscles. Biochim Biophys Acta. 1862(11):2168-2176. doi: 10.1016/j.bbadis.2016.08.020
Diao F, Mena W, Shi J, Park D, Diao F, Taghert P, Ewer J, and White BH. The splice Isoforms of the Drosophila Ecdysis Triggering Hormone receptor have developmentally distinct roles. Genetics, 202(1):175-89
Díaz J, Woudt L, Suazo L, Garrido C, Caviedes P, Cárdenas AM, Castiglioni C, Bevilacqua JA. (2016) Broadening The Imaging Phenotype of Dysferlinopathy at Different Disease Stages. Muscle Nerve. 54(2):203-10. doi: 10.1002/mus.25045
Diaz-Franulic I, Poblete H, Miño G, Gonzalez C, andLatorre R(2016) Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels Ann. Rev. Biophys. 45:371-98
English NJ and Garate JA (2016) Near-microsecond human aquaporin 4 gating dynamics in static and alternating external electric elds: Non-equilibrium molecular dynamics. J Chem Phys. 145(8):085102. doi: 10.1063/1.4961072
Escalona Y, Garate JA, Araya-Secchi R, Huynh T, Zhou R, Pérez-Acle T. (2016) Exploring the Membrane Potential of Simple Dual-Membrane Systems as Models for Gap-Junction Channels. Biophys J. 110(12):2678-88. doi: 10.1016/j.bpj.2016.05.005.
Ewer J. (2016) Como elegir un horario para Chile. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 9-13.
Fernández A, Pupo A, Mena-Ulecia K and Gonzalez C (2016) Pharmacological modulation of proton channel Hv1 in cancer therapy: Future perspectives Mol Pharmacol 90(3):385-402
Flaven-Pouchon J, Farine JP, Ewer J, Ferveur JF.(2016) Regulation of cuticular hydrocarbon profile maturation by Drosophila tanning hormone, bursicon, and its interaction with desaturase activity. Insect Biochem Mol Biol. 79:87-96. doi: 10.1016/j.ibmb.2016.10.007
Garate JA, Pérez-Acle T. (2016) From dimers to collective dipoles: Structure and dynamics of methanol/ethanol partition by narrow carbon nanotubes. J Chem Phys. 144(6):064105
García IE, Bosen F, Mujica P, Pupo A, Flores-Muñoz C, Jara O, Gonzalez C, Willecke K and Martínez AD (2016) From Hyperactive Connexin26 Hemichannels to Impairments in Epidermal Calcium Gradient and Permeability Barrier in the Keratitis-Ichthyosis-Deafness Syndrome J Invest Dermatol. 136(3):574-83
García IE, Prado P, Pupo A, Jara O, Rojas-Gómez D, Mujica P, Flores-Muñoz C, González-Casanova J, Soto-Riveros C, Pinto BI, Retamal MA,Gonzalez Cand Martínez AD (2016) Connexinopathies: a structural and functional glimpse. BMC Cell Biology. 17 Suppl 1:17. Doi: 10.1186/s12860-016-0092-x
Graham Z, Collier L, QinW, Peng Y, Sáez JC , Bauman WA and Christopher Cardozo. (2015) J A soluble activin receptor IIB fails to prevent muscle atrophy in a mouse model of spinal cord injury. J Neurotrauma 33(12):1128-35. doi: 10.1089/neu.2015.405
Johnson RG, Le HC, Evenson K, Loberg SW, Myslajek TM, Prabhu A, Manley AM, O’Shea C, Grunenwald H, Haddican M, Fitzgerald PM, Robinson T, Cisterna BA, Sáez JC, Liu TF, Laird DW, Sheridan JD. (2016) Connexin Hemichannels: Methods for Dye Uptake and Leakage. J Membr Biol.249(6):713-741
Krick S, Wang J, St-Pierre M, Gonzalez C, Dahl G, Salathe M. (2016) Duox2 Regulates Pannexin1-mediated ATP Release in Primary Human Airway Epithelial Cells via changes in intracellular pH and not H2O2 production. J Biol Chem. 291(12):6423-32. doi: 10.1074/jbc.M115.664854.
Lions S and Peña M Reading Comprehension in Latin America: Difficulties and Possible Interventions New Dir Child Adolesc Dev. 2016(152):71-84. doi: 10.1002/cad.20158.
Márquez-Miranda V, Araya-Durán I, Camarada MB, Comer J, Valencia-Gallegos JA, Gonzalez-Nilo FD. (2016) Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction. Sci Rep. 2016 Jul 5;6:29436. doi: 10.1038/srep29436.
Márquez-Miranda V, Peñaloza JP, Araya-Durán I, Reyes R, Vidaurre S, Romero V, Fuentes J, Céric F, Velásquez L, Gonzalez-Nilo F, Otero C. (2016) Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake. Nanoscale Res Lett. 2016 Dec;11(1):66.
Marracino P, Liberti M, Trapani E, Burnham CJ, Avena M, Garate JA, Apollonio F, English NJ. (2016) Human Aquaporin 4 Gating Dynamics under Perpendicularly-Oriented Electric-Field Impulses: A Molecular Dynamics Study. Int J Mol Sci. 17(7). pii: E1133. doi: 10.3390/ijms17071133.
Martin AJ, Dominguez C, Contreras-Riquelme S, Holmes DS, Pérez-Acle T. (2016) Graphlet Based Metrics for the Comparison of Gene Regulatory Networks. PLoS One. 2016 Oct 3;11(10):e0163497. doi: 10.1371/journal.pone.0163497.
Martínez AD, Jara O, Ceriani R, Maripillán J, Mujica P, García IE (2016) Methods to determinate formation of heteromeric hemichannels. Book title: Gap Junction and Pannexin Channels “A Volume in the Methods in Signal Transduction Series”. Chapter 11.
Mena W, Diegelmann S, Wegener C, Ewer J. (2016) Stereotyped responses of Drosophila peptidergic neuronal ensemble depend on downstream neuromodulators. Elife. 2016 Dec 15;5. pii: e19686. doi: 10.7554/eLife.19686.
Moldenhauer H, Diaz-Franulic I, Gonzalez-Nilo F,Naranjo D (2016). Effective pore size and radius of capture for K+ ions in K-channels. Scientific Reports. 6:1989
Moya-Díaz J, Álvarez JD, Montenegro M, Bayonés L, Belingheri AV, González-Jamett AM, Cárdenas AM, Marengo FD (2016) Sustained exocytosis after action potential-like stimulation at low frequencies in mouse chromaffin cells depends on a dynamin-dependent fast endocytotic process. Front Cell Neurosci. 10:184. doi: 10.3389/fncel.2016.00184
Moya Vera PR. (2016) Interacciones genético-ambientales en el comportamiento. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 28-32.
Muñoz P, Estay C, Díaz P, Elgueta C, Ardiles ÁO, Lizana PA (2016)Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats. Neural Plast. 2016:4783836. doi: 10.1155/2016/4783836.
Naranjo D, Moldenhauer H, Pincuntureo M. and Diaz-Franulic I (2016) Pore size matters for potassium channel conductance. J Gen Physiol 148(4):277-91. doi: 10.1085/jgp.201611625.
Olivares, J. (2016) Reseña bibliográfica sobre la araña de rincón (Loxosceles Laeta, Fam. Sicariirae): Que sabemos y que necesitamos saber. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 53-56.
Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S. (2016) CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory. Neuron. 92(1):75-83. doi: 10.1016/j.neuron.2016.09.002
Pérez-Núñez R, Barraza N, Gonzalez-Jamett A, Cárdenas AM, Barnier JV, Caviedes P. (2016) Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and Extension. Neurotox Res. 30(1):76-87. doi: 10.1007/s12640-016-9613-
Pinto BI, García IE, Pupo A, Retamal MA,Martínez AD,Latorre R andGonzalez C (2016) Charged residues at the first transmembrane region contribute to the voltage dependence of connexins slow gate. J Biol Chem 291(30):15740-52. doi: 10.1074/jbc.M115.709402
Puebla C, Cisterna BA, Salas DP, Delgado-López F, Lampe PD, Sáez JC. (2016) Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism. Biochim Biophys Acta. 1861(5):439-48
Qiu F, Chamberlin A, Watkins BM, Ionescu A, Perez ME, Barro-Soria R, Gonzalez C, Noskov SY and Larsson HP (2016) Molecular mechanism of Zn2+ inhibition of a voltage-gated proton channel. Proc Natl Acad Sci U S A 113(40):E5962-E5971
Retamal MA, García IE, Pinto B, Pupo A, Baez-Nieto D, Stehberg J, Del Rio R, Gonzalez C. (2016) Extracellular cysteine in connexins: role as redox sensors. Front in Physiol 7:1
Sáez JC. (2016) Proceedings of the International Gap Junction Conference 2015. BMC Cell Biol. 17 Suppl 1:18. doi: 10.1186/s12860-016-0097-5
Salazar C, Valdivia G, Ardiles AO, Ewer J, Palacios AG. (2016). Genetic variants associated with neurodegenerative Alzheimer disease in natural model. Biological Research. Special Issue. 26;49(1):14
Salvador-Morales C, Brahmbhatt B, Márquez-Miranda V, Araya-Duran I, Canan J, Gonzalez-Nilo F, Vilos C, Cebral J, Mut F, Lohner R, Leong B, Sundaresan G, Zweit J. (2016) Mechanistic Studies on the Self-Assembly of PLGA Patchy Particles and Their Potential Applications in Biomedical Imaging. Langmuir. 32(31):7929-42. doi: 10.1021/acs.langmuir.6b02177
Savalli N, Pantazis A,Sigg D, Weiss JN, Neely A and Olcese R (2016) The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials J Gen Physiol. 148(2):147-59. doi: 10.1085/jgp.201611586
Sepúlveda-Crespo D, Vacas-Córdoba E, Márquez-Miranda V, Araya-Durán I, Gómez R, Mata FJ,Gonzalez-Nilo FD, Muñoz-Fernández MÁ. (2016) Effect of Several HIV Antigens Simultaneously Loaded with G2-NN16 Carbosilane Dendrimer in the Cell Uptake and Functionality of Human Dendritic Cells. Dec 21;27(12):2844-2849. doi: 10.1021/acs.bioconjchem.6b00623.
Valdés J, Trachsel-Moncho L, Sahaboglu A, Trifunovic D, Miranda M, Ueffing M, Paquet-Durand F, Schmachtenberg O (2016). Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies. ALTEX,33(4):459-464
Vielma, A.H. and Schmachtenberg O. Electrophysiological fingerprints of OFF bipolar cells in rat retina. Sci. Rep.,6:30259 doi: 10.1038/srep30259
Wang H, Ardiles A, Yang S, Valdivia G, Baek M, Tran T, Posada-Duque R, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A. (2016). Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the hippocampus. Journal of Neuroscience 36(5):1723-9
Aguayo D, Pacheco N, Morales EH, Collao B, Luraschi R, Cabezas C, Calderón P, Gonzalez-Nilo F, Gil F, Calderón IL, Saavedra CP (2015) Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel. Arch Biochem Biophys. 568:38-45 Doi: 10.1016/j.abb.2015.01.005
Arias-Darraz L, Cabezas D, Colenso CK, Alegría-Arcos M, Bravo-Moraga F, Varas-Concha I, Almonacid DE, Madrid R, Brauchi S. (2015) A transient receptor potential ion channel in Chlamydomonas shares key features with sensory transduction-associated TRP channels in mammals. Plant Cell. 27(1):177-88. Doi: 10.1105/tpc.114.131862.
Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y,Pérez-Acle T, Skerrett IM (2015) Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32. J Biol Chem. 290(28):17074-84 Doi: 10.1074/jbc.M115.650747
Camarada MB, Márquez-Miranda V, Araya-Durán I, Yévenes A, Gonzalez-Nilo F. (2015) PAMAM G4 dendrimers as inhibitors of the iron storage properties of human L-chain ferritin. Phys Chem Chem Phys. 17(29):19001-11. Doi: 10.1039/c5cp02594j
Carrasquel-Ursulaez W, Contreras GF, Sepúlveda R, Aguayo D,Gonzalez-Nilo F, Gonzalez C and Latorre R. (2015) Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel. J Gen Physiol. 145(1):61-74. Doi: 10.1085/jgp.201411194
Carrasquel-Ursulaez W, Moldenhauer H, Castillo JP, Latorre R & Alvarez O. (2015) Biophysical analysis of thermosensitive TRP channels with a special focus on the cold receptor TRPM8. Temperature. 145(1):61-74. oi: 10.1080/23328940.2015.1047558
Castillo, JP, Rui, H, Basilio, D, Das, A, Roux, B, Latorre R, Bezanilla, F, Holmgren, M. (2015). Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase. Nature Comm. 6:7622. oi: 10.1038/ncomms8622
Castillo K, Contreras GF, Pupo A, Torres Y, Neely A,Gonzalez C and Latorre R. (2015) Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels. Proc Natl Acad Sci U S A. 112(15):4809-14. Doi: 10.1073/pnas.1504378112
Castillo K, Pupo A, Baez-Nieto D, Contreras G; Morera FJ, Neely A, Latorre R, Gonzalez C. (2015) Voltage-Gated Proton (Hv1) Channels, a Singular Voltage Sensing Domain. FEBS Letters . 589(22):3471-8 Doi: 10.1016/j.febslet.2015.08.003.
Cerquera A, Muñoz J, Araya J, Gómez O (2015) Registro de actividad eléctrica en la retina de una rata albina empleando una matriz de microelectrodos. Acta biológica colombiana 20(3):37-46. Doi: 10.15446/abc.v20n3.46216
Diao F, Ironfield H, Diao F, Luan H, Shropshire W, Ewer J, Marr E, Potter CJ, Landgraf M and White BH (2015) Plug-and-Play Genetic Access to Drosophila Cell Types Using Exchangeable Exon Cassettes. Cell Reports. 10(8):1410-21. Doi: 10.1016/j.celrep.2015.01.059
Diaz-Franulic I., Sepúlveda R, Navarro-Quezada N, F. Gonzalez-Nilo FD and Naranjo D. (2015). Pore dimensions and the role of occupancy in unitary conductance of Shaker K-channels. The Journal of General Physiology.146:133-146. Doi: 10.1085/jgp.201411353.
Du LY, Chang LY, Ardiles AO, Tapia-Rojas C, Araya J, Inestrosa NC, Palacios AG, Acosta ML. (2015) Alzheimer’s disease-related protein expression in the retina of Octodon degus. PLoS One. 2015 Aug 12;10(8):e0135499. oi: 10.1371/journal.pone.0135499
Duran-Lara EF, Avila-Salas F, Galaz S, John A, Marican A, Gutierrez M, Nachtigall FM, Gonzalez-Nilo FD, Santos LS. (2015) Nano-Detoxification Of Organophosphate Agents By PAMAM Derivatives. J Braz Chem Soc 26(3): 580-91. Doi: 10.5935/0103-5053.20150013
Durán-Lara EF, López-Cortés XA, Castro RI, Avila-Salas F, Gonzalez-Nilo FD, Laurie VF, Santos LS. (2015) Experimental and theoretical binding affinity between polyvinylpolypyrrolidone and selected phenolic compounds from food matrices. Food Chem. 168:464-70. oi: 10.1016/j.foodchem.2014.07.048
Elgueta C, Vielma AH,Palacios AG and Schmachtenberg O. (2015) Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells. Front. Cell. Neurosci. 9:6 Doi: 10.3389/fncel.2015.00006
Ferreira G, Raddatz N, Lorenzo Y, Gonzalez C and Latorre R (2015) Biophysical and Molecular Features of Thermosensitive TRP Channels Involved in Sensory Transduction . Cahpter in: TRP Channels in Sensory Transduction, R. Madrid, J. Bacigalupo (eds.). Springer International Publishing Switzerland
García IE, Maripillán J, Jara O, Ceriani R, Palacios-Muñoz A, Ramachandran J, Olivero P, Pérez-Acle T,Gonzalez C,Sáez JC, Contreras JE,Martínez AD. (2015)Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43. J Invest Dermatol. 135(5):1338-47. oi: 10.1038/jid.2015.20
Garcia-Elias A, Berna-Erro A, Rubio-Moscardo F, Pardo-Pastor C, Mrkonjić S, Sepúlveda RV, Vicente R, Gonzalez-Nilo FD, Valverde MA. (2015) Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels. Structure. 23(8):1404-13. Doi: 10.1016/j.str.2015.05.018
García-Puente Y, Prado-Gutiérrez P, Martínez-Montes E (2015) Time-frequency methods for studying non-stationary auditory responses. IFMBE Proceedings. 49: 540-543. https://doi.org/10.1007/978-3-319-13117-7_138
García-Puente Y, Prado-Gutiérrez P, Martínez-Montes (2015) Evaluación de métodos para la estimación de la respuestaauditiva de seguimiento de la modulación. CENIC Ciencias Biologicas.
Harcha PA, Vargas A, Yi C, Koulakoff AA, Giaume C, Sáez JC . (2015) Hemichannels Are Required for Amyloid β-Peptide-Induced Degranulation and Are Activated in Brain Mast Cells of APPswe/PS1dE9 Mice. J Neurosci. 35(25):9526-38. Doi: 10.1523/JNEUROSCI.3686-14.2015
Inestrosa NC, Rios JA, Cisternas P, Tapia-Rojas C, Rivera D, Braidy N, Zolezzi JM, Godoy JA, Carvajal FJ, Ardiles AO, Bozinovic F, Palacios AG, Sachdev PS. (2015). Age progression of neuropathological markers in the brain of the Chilean rodent Octodon degus, a natural model of Alzheimer’s disease. Brain Pathology. 25(6):679-91. Doi: 10.1111/bpa.1222
Kalinowska M, Chávez AE, Lutzu S, Castillo PE, Bukauskas FF, Francesconi A. Actinin-4 (2015) Governs Dendritic Spine Dynamics and Promotes Their Remodeling by Metabotropic Glutamate Receptors. J Biol Chem. 290(26):15909-20. Doi: 10.1074/jbc.M115.640136
Krüger E. Mena W, Lahr EC, Johnson EC and Ewer J. (2015). Genetic analysis of Eclosion Hormone action during Drosophila larval ecdysis. Development, 142(24):4279-4287. Doi: 10.1242/dev.126995
Langenhan T, Barr MM, Bruchas MR, Ewer J, Griffith LC, Maiellaro I, Taghert PH, White BH, Monk KR (2015) Model Organisms in GPCR Research. Mol Pharmacol. 88(3):596-603. Doi: 10.1124/mol.115.098764
Leiva V, Tejo M, Guiraud P, Schmachtenberg O, Orio P and Marmolejo-Ramos F. Modeling neural activity with cumulative damage distributions. Biological Cybernetics. 109(4-5):421-33. Doi: 10.1007/s00422-015-0651-9
López-Cabaña ZE, Valdés O, Vergara CE, Camarada MB, Nachtigall FM, Gonzalez-Nilo FD, Santos LS (2015) Photophysical Studies Of The Interactions Of Poly(amidoamine) Generation Zero (PAMAM G0) With Copper And Zinc Ions. Journal Of Luminescence 164:23-30. Doi: 10.1016/j.jlumin.2015.03.019
Márquez-Miranda V, Camarada MB, Araya-Durán I, Varas-Concha I, Almonacid DE, Gonzalez-Nilo F. (2015) Biomimetics: From Bioinformatics to Rational Design of Dendrimers as Gene Carriers. PLoS One. 10(9):e0138392. Doi: 10.1371/journal.pone.013839
Miño-Galaz GA. (2015) Allosteric Communication Pathways and Thermal Rectification in PDZ‑2 Protein: A Computational Study J. Phys Chem B . 119(20):6179-89. Doi: 10.1021/acs.jpcb.5b02228
Miño-Galaz GA, Gutierrez G (2015) Hydrogen bonds and asymmetrical heat diffusion in alpha helices. A computational analysis Chemical Physics Letters 635:16-2. Doi: 10.1021/acs.jpcb.5b02228
Morales-Camilo N, Salas CO, Sanhueza C, Espinosa-Bustos C, Sepúlveda-Boza S, Reyes-Parada M,Gonzalez-Nilo F, Caroli Rezende M, Fierro A. (2014) Synthesis, biological evaluation and molecular simulation of chalcones and aurones as selective MAO-B inhibitors. Chem Biol Drug Des. 85(6):685-95 Doi: 10.1111/cbdd.12458
Morera FJ, Baez-Nieto D, Lorenzo Y, Castillo K, Pupo A, Vargas-Chacoff L andGonzalez C (2015) Role of ion channels in salt secretion by atlantic salmon gills during acclimation to seawater. Physiological Mini Reviews, 8(1)
Morera FJ, Saravia J, Pontigo JP, Vargas-Chacoff L, Contreras GF, Pupo A, Lorenzo Y, Castillo K, Tilegenova C, Cuello LG, Gonzalez C. (2015) Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: new therapeutics opportunities as targets in human diseases. Pharmacol Res. 101:56-64 Doi: 10.1016/j.phrs.2015.08.011
Naranjo D, Wen H and Brehm P (2015). Zebrafish CaV2.1 Calcium Channels Are Tailored for Fast Synchronous Neuromuscular Transmission. Biophysical Journal 108(3):578-84. Doi: 10.1016/j.bpj.2014.11.3484
Olivares E, Orio P. (2015) Mathematical Modeling of TRPM8 and the Cold Thermoreceptors. In: TRP Channels in Sensory Transduction. Madrid, R.; Bacigalupo, J.,editors. Springer International Publishing
Olivares E, Salgado S, Maidana JP, Herrera G, Campos M, Madrid R and Orio P (2015). TRPM8-dependent dynamic response in a mathematical model of cold thermoreceptor. PLOS One 588(Pt 17):3141-8 Doi: 10.1371/journal.pone.0139314
Poblete H, Oyarzún I, Olivero P, Comer J, Zuñiga M, Sepulveda RV, Báez-Nieto D, Gonzalez Leon C, Gonzalez-Nilo F, Latorre R. (2015) Molecular Determinants of Phosphatidylinositol 4,5Bisphosphate (PI(4,5)P2) Binding to Transient Receptor Potential V1 (TRPV1) Channels. J Biol Chem. 290(4):2086-98. Doi: 10.1074/jbc.M114.613620
Prado-Gutierrez P, Castro-Fariñas A, Morgado-Rodriguez L, Velarde-Reyes E, Martínez AD, Martínez-Montes E. (2015) Habituation of auditory steady state responses evoked by amplitude-modulated acoustic signals in rats. Audiology Research 5(113):21-28. Doi: 10.4081/audiores.2015.113
Retamal MA, Leon-Paravic CG, Ezquer M, Ezquer F, Del Rio R, Pupo A, Martínez AD, Gonzalez C (2015) Carbon Monoxide: A New Player in the Redox Regulation of Connexin Hemichannels. IUBMB Life 67(6):428-37. Doi: 10.1002/iub.1388
Retamal MA, Reyes EP, García IE, Pinto B, Martínez ADGonzalez C (2015) Diseases associated with leaky hemichannels. Frontiers in Cellular Neuroscience. 9:267. Doi: 10.3389/fncel.2015.00267
Riquelme MA, Cea LA, Vega JL, Puebla C, Vargas AA, Shoji KF, Subiabre M, Sáez JC. (2015) Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation. Front Cell Dev Biol. 3:25. Doi: 10.3389/fcell.2015.00025
Rivas-Aravena A, Fuentes Y, Cartagena J, Brito T, Poggio V, La Torre J, Mendoza H, Gonzalez-Nilo F, Sandino AM, Spencer E. (2015) Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant. Fish Shellfish Immunol. 45(1): 157-166. Doi: 10.1016/j.fsi.2015.03.033
Rovegno M, Soto PA, Sáez PJ, Naus CC,Sáez JC and von Bernhardi R. (2015) Connexin43 hemichannels mediate secondary cellular damage spread from the trauma zone to distal zones in astrocyte monolayers. Glia 63(7):1185-99. Doi: 10.1002/glia.22808
Sáez JC, Cisterna BA, Vargas A, Cardozo CP. (2015) Regulation of pannexin and connexin channels and their functional role in skeletal muscles. Cell Mol Life Sci. 72(15):2929-35. Doi: 10.1007/s00018-015-1968-1
Salas D, Puebla C, Lampe PD, Lavandero S, Sáez JC. (2015) Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition. Biochim Biophys Acta. 1852(7):1268-1277. Doi: 10.1016/j.bbadis.2015.03.004
Suzuki K, Lovera M,Schmachtenberg O and Couve E. (2015) Axonal Degeneration in Dental Pulp precedes Primary Teeth Exfoliation. J Dental Res. 94(10):1446-53. Doi: 10.1177/0022034515593055
Talaverón R, Fernández P, Escamilla R, Pastor AM, Matarredona ER, Sáez JC (2015) Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells. Front Cell Neurosci. 9:411. Doi: 10.3389/fncel.2015.00411
Tindi JO, Chávez AE, Cvejic S, Calvo-Ochoa E, Castillo PE, Jordan BA. (2015) ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 35(24):8986-96. Doi: 10.1523/JNEUROSCI.4029-14.2015.
Valdés, J, Olivares J, Ponce D, and Schmachtenberg O (2015) Analysis of olfactory sensitivity in rainbow trout (Oncorhynchus mykiss) reveals their ability to detect lactic acid, pyruvic acid and four B-vitamins. Fish Physiol. Biochem., 41(4):879-85. Doi: 10.1007/s10695-015-0054-9
Valdés O, Vergara CE, Camarada MB, Carrasco-Sánchez V, Nachtigall FM, Tapia J, Fischer R, Gonzalez-Nilo FD, Santos LS. (2014) Synthesis and characterization of an insoluble polymer based on polyamidoamine: Applications for the decontamination of metals in aqueous systems. J Environ Manage. 147:321-9. Doi: 10.1016/j.jenvman.2014.09.021
Whitlock KE. (2015) The loss of scents: Do defects in olfactory sensory neuron development underlie human disease? Birth Defects Res C Embryo Today. 105(2):114-25. Doi: 10.1002/bdrc.21094
Abarca F, Gutierrez-Maldonado SE, Parada P, Martinez P, Maass A and Pérez-Acle T(2014) Insights on the structure and stability of Licanantase: a trimeric acid-stable coiled-coil lipoprotein from Acidithiobacillus thiooxidans. Peer J. 2:e457. Doi: 10.7717/peerj.457.
Araya-Secchi R, Pérez-Acle T , Seung-gu Kang, Huynh T, Bernardin A, Escalona Y, Garate JA, Martínez AD, García IE,Sáez JCand Zhou R (2014) Characterization of a Novel Water Pocket Inside the Human Cx26 Hemichannel Structure. Biophysical Journal, 107:599-612. Doi: 10.1016/j.bpj.2014.05.037
Ardiles AO, Flores-Muñoz C, Toro-Ayala G, Cárdenas AM, Palacios AG, Muñoz P, Fuenzalida M, Sáez JC, Martínez AD. (2014). Pannexin 1 regulates the bidirectional hippocampal synaptic plasticity in the adult mice. Front Cell Neurosci. 8:326. Doi: 10.3389/fncel.2014.00326.
Arenas-Salinas M, Ortega-Salazar S, Gonzalez-Nilo FD, Pohl E, Holmes DS, Quatrini R. (2014) AFAL: a web service for profiling amino acids surrounding ligands in proteins. J Comput Aided Mol Des. 28(11):1069-76. Doi: 10.1007/s10822-014-9783-6.
Arenas-Salinas M, Townsend PD, Brito C, Marquez V, Marabolli V, Gonzalez-Nilo F, Matias C, Watt RK, López-Castro JD, Domínguez-Vera J, Pohl E, Yévenes A. (2014) The crystal structure of ferritin from Chlorobium tepidum reveals a new conformation of the 4-fold channel for this protein family. Biochimie. 106:39-47 Doi: 10.1016/j.biochi.2014.07.019.
Baez D, Raddatz N, Ferreira G, Gonzalez C, Latorre R.(2014) Gating of Thermally Activated Channels. In: Thermal Sensors. L. Islas and F. Qin. Eds. Current Topics in Membranes. 74:51-87. Doi: 10.1016/B978-0-12-800181-3.00003-8.
Bhakat S, Martin AJ, Soliman ME. (2014) An integrated molecular dynamics, principal component analysis and residue interaction network approach reveals the impact of M184V mutation on HIV reverse transcriptase resistance to lamivudine. Mol Biosyst. 10(8):2215-28. Doi: 10.1039/c4mb00253a.
Brito C, Matias C, Gonzalez-Nilo FD, Watt RK, Yévenes A. (2014) The C-Terminal Regions Have an Important Role in the Activity of the Ferroxidase Center and the Stability of Chlorobium tepidum Ferritin. Protein J. 33(3):211-20 Doi: 10.1007/s10930-014-9552-3.
Cárdenas JP, Olivares G, Cabrera F, Alfaro R, Goya D, Samaniego H, Gibert J, Palacios AG. Redes complejas: un caso de estudio sobre la colaboración científica. En: Las Rutas de la complejidad. Edmundo Bustos A, Pablo A. Marquet, Adrián G. Palacios Editores. Ediciones Instituto de Sistemas Complejos de Valparaíso, Valparaiso, Chile, 211p
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Chang LYL, Lowe J, Ardiles A, Lim J, Grey AC, Robertson K, Danesh-Meyer H, Palacios AG, Acosta ML (2014). Alzheimer’s disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers. Alzheimer’s & Dementia. 10(2):251-261. Doi: 10.1016/j.jalz.2013.06.004.
Cisterna BA, Cardozo C and Sáez JC (2014) Neuronal involvement in muscular atrophy. Front. Cell. Neurosci. 8:405. Doi: 10.3389/fncel.2014.00405
Cornejo I, Andrini O, Niemeyer MI, Marabolí V, Gonzalez-Nilo FD, Teulon J, Sepúlveda FV, Cid LP. (2014) Identification and Functional Expression of a Glutamate- and Avermectin-Gated Chloride Channel from Caligus rogercresseyi, a Southern Hemisphere Sea Louse Affecting Farmed Fish. PLoS Pathog. 10(9):e1004402. Doi: 10.1371/journal.ppat.1004402.
Couve E, Osorio R, Schmachtenberg O (2014) Reactionary Dentinogenesis and Neuroimmune Response in Dental Caries. J Dent Res. 93(8):788-793. Doi: 10.1177/0022034514539507. Ewer J, Jindra M (2014). Development and regulation: Departing from paradigms. Editorial overview: Curr. Op. Insect Sci. 1: vii-ix. Doi: 10.1016/j.cois.2014.05.006
Figueroa VA, Retamal MA, Cea LA, Salas JD, Vargas AA, Verdugo CA, Jara O, Martínez AD and Sáez JC (2014) Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca2+ signaling in HeLa cells. Front. Cell. Neurosci. 8:265. Doi: 10.3389/fncel.2014.00265.
Garate JA, Pérez-Acle T and Oostenbrink C (2014) On the thermodynamics of carbon nanotube single-file water loading: Free energy, Energy and Entropy calculations Phys. Chem. Chem. Phys. 16(11):5119-28. Doi: 10.1039/c3cp54554g.
González-Jamett AM, Haro-Acuña V, Momboisse F, Caviedes P, Bevilacqua JA, Cárdenas AM. (2014) Dynamin-2 in nervous system disorders. Journal of Neurochemistry. 128(2):210-23. Doi: 10.1111/jnc.12455.
Gonzalo Hernández, Carlos Jaime Barrios Hernández, Gilberto Díaz, Carlos Garcia Garino, Sergio Nesmachnow, Pérez-Acle T, Mario Storti, Mariano Vasquez (Editors). High Performance Computing. Communications in Computer and Information Science. First HPCLATAM – CLCAR Latin American Conference CARLA 2014. Springer-Verlag Berlin Heidelberg 2014. ISBN 978-3-662-45482-4
Jabba S, Goyal R, Sosa-Pagán JO, Moldenhauer H, Wu J, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. (2014) Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six. Neuron. 82(5):1017-31. Doi: 10.1016/j.neuron.2014.04.016.
Le HT, Sin WC, Lozinsky S, Bechberger J, Vega JL, Guo XQ, Sáez JC, Naus CC. (2014) Gap junction intercellular communication mediated by connexin43 in astrocytes is essential for their resistance to oxidative stress. J Biol Chem. 289(3):1345-54. Doi: 10.1074/jbc.M113.508390.
Leiva A, Fuentes I, Bossel E, Urzua M, Mendez M, Pino M, Radic D, Márquez V, Gonzalez-Nilo FD (2014) Block Copolymers In The Synthesis Of Gold Nanoparticles. Two New Approaches: Copolymer Aggregates As Reductants And Stabilizers And Simultaneous Formation Of Copolymer Aggregates And Gold Nanoparticles. J Of Polymer Science, 2014. 52(21):3069–79. Doi:10.1002/pola.27354
Martín P, Moncada M, Enrique N, Asuaje A, Valdez Capuccino JM, Gonzalez C, Milesi V. (2014) Arachidonic acid activation of BKCa (Slo1) channels associated with the β 1 subunit in human vascular smooth muscle cells. Pflügers Archiv European Journal of Physiology 466(9):1779-92. Doi: 10.1007/s00424-013-1422-x.
Miño G, Barriga R, Gutierrez G. (2014) Hydrogen Bonds And Heat Diffusion In Α-Helices: A Computational Study. The Journal Of Physical Chemistry B. 118(34):10025-34. Doi: 10.1021/jp503420e.
Moldenhauer H, Latorre R Grandl J. (2014) The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-Methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole. PLoS One. 9(9):e106776. Doi: 10.1371/journal.pone.0106776.
Momboisse F, Olivares MJ, Báez-Matus X, Guerra MJ, Flores-Muñoz C, Sáez JC, Martínez AD , Cárdenas AM. (2014) Pannexin 1 channels: new actors in the regulation of catecholamine release from adrenal chromaffin cells. Front Cell Neurosci. 8:270. Doi: 10.3389/fncel.2014.00270.
Monrás JP, Collao B, Molina-Quiroz RC, Pradenas GA, Saona LA, Durán-Toro V, Ordenes-Aenishanslins N, Venegas FA, Loyola DE, Bravo D, Calderón PF, Calderón IL, Vásquez CC, Chasteen TG, Lopez DA, Pérez-Donoso JM. (2014) Microarray analysis of the Escherichia coli response to CdTe-GSH Quantum Dots: understanding the bacterial toxicity of semiconductor nanoparticles. BMC Genomics, 15(1):1099. Doi: 10.1186/1471-2164-15-1099.
Neely A, Hidalgo P. (2014) Structure-function Of Proteins Interacting With The Α1 Pore-forming Subunit Of High-voltage-activated Calcium Channels. Front Physiol. 5:209 Doi: 10.3389/fphys.2014.00209.
Negrón-Oyarzo I, Pérez MA, Terreros G, Munoz P, Dagnino-Subiabre A. (2014) Effects of Chronic Stress in Adolescence on Learned Fear, Anxiety, and Synaptic Transmission in the rat Prelimbic Cortex. Behav Brain Res. 259:342-53. Doi: 10.1016/j.bbr.2013.11.001.
Olivares MJ, González-Jamett AM, Guerra MJ, Baez-Matus X, Haro-Acuña V, Martínez-Quiles N, Cárdenas AM. (2014) Src Kinases Regulate De Novo Actin Polymerization during Exocytosis in Neuroendocrine Chromaffin Cells. PLoS One. 2014 9(6):e99001. Doi: 10.1371/journal.pone.0099001.
Orellana JA,Sáez JC, Bennett MV, Berman JW, Morgello S, Eugenin EA. (2014) HIV increased the release of dickkopf-1 (DKK1) protein from human astrocytes by a Cx43 hemichannel-dependent mechanism. J Neurochem. 128(5):752-63 . Doi: 10.1111/jnc.12492.
Palacios-Munoz A, Escobar MJ, Vielma A, Araya J, Astudillo A, Garcia IE, Valdivia G, Hurtado J, Schmachtenberg O, Martínez AD, Palacios AG (2014) Role Of Connexin Channels In The Retinal Light Response Of A Diurnal Rodent. Frontiers In Cellular Neuroscience. 8:249. Doi: 10.3389/fncel.2014.00249.
Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. (2014) Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proc Natl Acad Sci U S A. 111(51):18381-6. Doi: 10.1073/pnas.1411127112
Pezo D, Soudry D and Orio P (2014). Diffusion approximation-based simulation of stochastic ion channels: which method to use?. Front. Comput. Neurosci. 8:139. Doi: 10.3389/fncom.2014.00139.
Pupo A, Báez-Nieto D, Martínez A, Latorre R,Gonzalez C (2014) Proton Channel Models: Filling The Gap Between Experimental Data And The Structural Rationale. Channels (Austin). 8(3):180-192. Doi: 10.4161/chan.286658(3):180-192
Pupo A, Gonzalez León C. (2014) In pursuit of an inhibitory drug for the proton channel. Proc Natl Acad Sci U S A. 111(27):9673-4. Doi: 10.1073/pnas.1408808111
Raddatz N, Castillo JP,Gonzalez C , Alvarez O, Latorre R (2014) Temperature And Voltage Coupling To Channel Opening In Transient Receptor Potential Melastatin 8 (TRPM8). J Biol Chem. 289(51):35438-54 Doi: 10.1074/jbc.M114.612713.
Retamal MA, Alcayaga J, Bultynck G, Leybaer L, Sáez PJ, Fernandez R, León LE and Sáez JC (2014) Opening of pannexin and connexin based-channels increases the excitability of nodose ganglion sensory neurons. Front. Cell. Neurosci. Front. Cell. Neurosci. 8:158. Doi: 10.3389/fncel.2014.00158.
Retamal MA, Sáez JC . (2014) Hemichannels; from the molecule to the function. Front Physiol. 5:411. Doi: 10.3389/fphys.2014.00411.
Retamal MJ, Cisternas MA, Gutierrez-Maldonado SE, Pérez-Acle T, Seifert B, Busch M, Huber P, Volkmann UG. (2014) Towards Bio-silicon Interfaces: Formation Of An Ultra-thin Self-hydrated Artificial Membrane Composed Of Dipalmitoylphosphatidylcholine (DPPC) And Chitosan Deposited In High Vacuum From The Gas-phase. J Chem Phys. 141(10):104201. Doi: 10.1063/1.4894224.
Sáez JC, Leybaert L. (2014) Hunting for connexin hemichannels. FEBS Lett. 588(8):1205-1211. Doi: 10.1016/j.febslet.2014.03.004.
Sáez PJ, Shoji KF, Aguirre A, Sáez JC. (2014) Regulation Of Hemichannels And Gap Junction Channels By Cytokines In Antigen-Presenting Cells. Mediators Inflamm. 2014:742734. Doi: 10.1155/2014/742734.
Schramm OG, López-Cortés X, Santos LS, Laurie VF, Gonzalez-Nilo FD, Krolik M, Fischer R, Di Fiore S. (2014) pH-dependent nano-capturing of tartaric acid using dendrimers. Soft Matter. 10(4):600-8. Doi: 10.1039/c3sm52255e.
Torres-Paz J, Whitlock KE . (2014) The olfactory sensory system develops from coordinated movements within the neural plate. Dev Dyn. 243(12):1619-31. Doi: 10.1002/dvdy.24194.
Torres YP, Granados ST, Latorre R (2014) . Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunits. Frontier in Physiology. 5:383 Doi: 10.3389/fphys.2014.00383.
Vielma AH, Agurto A, Valdes J, Palacios AG, Schmachtenberg O (2014) Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells. PLoS One, 9(12):e114330. Doi: 10.1371/journal.pone.0114330.
White BH, Ewer J. (2014) Neural and Hormonal Control of Postecdysial Behaviors in Insects. Annu Rev Entomol. 59:363-81. Doi: 10.1146/annurev-ento-011613-162028
Whitlock KE. (2014) Zebrafish Invade Valparaiso: Third Meeting and Symposium of the Latin American Zebrafish Network. Zebrafish. 11(6):580-582
Whitlock KE. & Ciencia al Tiro, 2014, La alegria de la Ciencia, Andros Impresores, Santiago, Chile 118 p.
Aguirre A, Maturana CJ, Harcha PA, Sáez JC. (2013) Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation. Mediators Inflamm. 2013:893521. Doi: 10.1155/2013/893521
Aguirre A, Shoji KF, Saez JC, Henriquez M, Quest AFG. (2013) FasL-Triggered death of jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between fas and the purinergic receptor P2X7. Journal of Cellular Physiology 228 (2): 485–493. Doi: 10.1002/jcp.24159
Almeyda Campos MV, Costa C, Gonzalez C, Latorre R, Milesi V, Ferreira G. 2013. New biomedical and physiological knowledge of the sport (with emphasis on ion channels in skeletal muscle). In “New Technologies and Innovation in Human Movement.” (Book VI REMH). Ed. Universidad de Chihuahua.
Ardiles A, Ewer J, Acosta ML, Kirkwood A, Martínez A, Ebensperger LA, Bozinovic F, Lee TM, Palacios AG. (2012). Octodon degus (Molina 1782): A model in comparative biology and biomedicine. Cold Spring Harbor Protocols. 2013(4): 312-18. Doi: 10.1101/pdb.emo071357
Bazáes A, Olivares J, Schmachtenberg O. (2013) Properties, projections and tuning of teleost olfactory receptor neurons. Journal of Chemical Ecology. 39(4):451-64. Doi: 10.1007/s10886-013-0268-1
Boric K, Orio P, Viéville T, Whitlock KE (2013). Quantitative analysis of cell migration using optical flow. PLOS One,8(7): e69574. Doi: 10.1371/journal.pone.0069574.
Castillo K, Valenzuela V, Matus S, Nassif M, Oñate M, Fuentealba Y, Encina G, Irrazabal T, Parsons G, Court FA, Schneider BL, Armentano D, Hetz C. (2013) Measurement of autophagy flux in the nervous system in vivo. Cell Death Dis. 14;4:e917. Doi: 10.1038/cddis.2013.421
Cea LA, Cisterna BA, Puebla C, Frank M, Figueroa XF, Cardozo C, Willecke K, Latorre R, Sáez JC. (2013) De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy. Proc Natl Acad Sci U S A. 110(40):16229-34. Doi: 10.1073/pnas.1312331110
Cessac B and Palacios AG. (2013) Spike train statistics from empirical facts to theory: the case of the retina. In Mathematical Problems in Computational Biology and Biomedicine. Cazals F, Kornprobst P, Springer, pag. 261-302. Doi:10.1007/978-3-642-31208-3_8
Contreras GF, Castillo K, Enrique N, Carrasquel-Ursulaez W, Castillo JP, Milesi V,Neely A, Alvarez O, Ferreira G, Gonzalez C, Latorre R. (2013) A BK (Slo1) channel journey from molecule to physiology. Channels (Austin). 7(6): 441-457. Doi: 10.4161/chan.26242
Couve E, Osorio R and Schmachtenberg O. (2013) The Amazing Odontoblast: Activity, Autophagy and Aging. J Dental Res.92(9):765-72. Doi: 10.1177/0022034513495874
Escobar MJ, Palacios AG. (2013). Beyond the retina neural coding: On Models and Neural Rehabilitation. Journal of Physiology Paris. 107(5):335-7. Doi: 10.1016/j.jphysparis.2013.08.002
Escobar MJ, Pezo D, Orio P. (2013) Mathematical analysis and modeling of motion direction selectivity in the retina. Journal of Physiology Paris. 107(5):349-59. Doi: 10.1016/j.jphysparis.2013.08.003
Figueroa XF, Lillo MA, Gaete PS, Riquelme M, Sáez JC. (2013) Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels. Neuropharmacology. 75: 471–478. Doi: 10.1016/j.neuropharm.2013.02.022
Figueroa V, Sáez PJ, Salas JD, Salas D, Jara O, Martínez AD, Saez JC , Retamal MA. (2013) Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway. Biochim Biophys Acta. 1828(3):1169-79 . Doi: 10.1016/j.bbamem.2012.12.006
Giaume C, Froger N, Orellana JA, Retamal M and Sáez JC. (2013) Role of microglial activation in astroglial connexin expression and function leading to neurotoxicity”. Connexin cell communication channels: roles on the immune system and immunopathology (ed. Oviedo-Orta, Kwak and Evans). Taylor and Francis publisher. Pag 219-232.
Giaume C, Leybaert L, C Naus C,Sáez JC. (2013) Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. Front Pharmacol. 2013;4:88. Doi: 10.3389/fphar.2013.00088
Gonzalez C, Rebolledo S, Perez M and Larsson HP. (2013) Molecular mechanism of voltage sensing in voltage-gated proton channels. Journal of General Physiology. 141(3):275-85. Doi: 10.1085/jgp.201210857
Gonzalez-Jamett AM, Momboisse F, Guerra MJ, Ory S, Baez-Matus X, Barraza N, Calco V, Houy S, Couve E, Neely A,Martínez A, Gasman S, Cárdenas AM (2013) Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLOS ONE, 8(8):70638.
González-Jamett AM, Momboisse F, Haro-Acuña V, Bevilacqua JA, Caviedes P,Cárdenas AM. (2013) Dynamin-2 Function and Dysfunction Along the Secretory Pathway. Front Endocrinol (Lausanne). 2013 Sep 18;4:126. Doi: 10.3389/fendo.2013.00126.
Gonzalez-Jamett AM, Momboisse F, Guerra MJ, Ory S, Baez-Matus X, Barraza N, Calco V, Houy S, Couve E,Neely A,Martínez AD, Gasman S, Cárdenas AM (2013) Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLOS ONE, 8(8):70638. Doi: 10.1371/journal.pone.0070638
Hernández-Salinas R, Vielma AZ, Arismendi MN, Boric MP, Sáez JC, Velarde V. (2013) Boldine Prevents Renal Alterations In Diabetic Rats. J Diabetes Res. 2013:593672. Doi: 10.1155/2013/593672
Johnson RG, Sáez JC. (2013) We’ve Had Important Advances in the Connexin/Pannexin Field, Yet There Is Still Much to Do Neuropharmacology. 75: 467–470. Doi: 10.1016/j.neuropharm.2013.08.011
Kozoriz MG, Lai S, Vega JL, Sáez JC, Sin WC, Bechberger JF, Naus CC. (2013) Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia. Neuropharmacology.75 (2013) 549-556. Doi: 10.1016/j.neuropharm.2013.05.003
Latorre R. and Báez-Nieto, D. (2013) Ca2+ activation of K+ channels: RCK domains. In: Encyclopedia of Biophysics. Springer Verlag. Gordon C.K. Roberts, editor. DOI 10.1007/978-3-642-16712-6.
Latorre R, Contreras G (2013) Keeping you healthy: BK channel activation by omega-3 fatty acids. Journal of General Physiology. 142:347-350. Doi: 10.1085/jgp.201311100
Latorre R, Gonzalez C, Rojas P. (2012) Signal-Transduction-Dependent Channels. Neuroscience in the 21st Century, Eugene Martin and Donald Pfaff, eds. Springer. 81-107. Doi: 10.1007/978-1-4614-1997-6_5
Latorre R, Morera FJ, Zaelzer C. (2013). Voltage-dependent K+ channels. In: Encyclopedia of Biological Chemistry. 2nd Edition. Lane, M.D and W.J. Lennarz, editors. Elsevier. Vol 1, pp. 399-404.
Ocampo-Garcés A, Hernandez F, Palacios AG. (2013). REM sleep phase preference in the crepuscular Octodon degus assessed by selective REM sleep deprivation. Sleep. 36(8):1247-56. Doi: 10.5665/sleep.2896
Orellana JA, Martínez AD, Retamal MA. (2013) Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules. Neuropharmacology. 75: 567–582
Orellana JA, Velasquez S, Williams DW, Sáez JC, Berman JW, Eugenin EA. (2013) Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes. J Leukoc Biol. 94(3):399-407. Doi: 10.1189/jlb.0512249
Osorio R, Schmachtenberg O (2013) Calcium-activated chloride channels do not contribute to the odorant transduction current in the marine teleost Isacia conceptionis. Journal of Fish Biology. 83 (5):1468-73. Doi: 10.1111/jfb.12253.
Palacios AG, Lee TM. (2012). Husbandry and Breeding in the Octodon degus (Molina 1782). Cold Spring Harbor Protocols. 2013(4): 350-53. Doi: 10.1101/pdb.prot073577
Pastor P, Cisternas P, Salazar K, Silva-Alvarez C, Oyarce K, Jara N, Espinoza F,Martínez AD and Nualart F (2013) SVCT2 vitamin C transporter expression in progenitor cells of the postnatal neurogenic niche. Frontiers in Cellular Neuroscience. 7:119. Doi: 10.3389/fncel.2013.00119
Ravanal MC, Alegría-Arcos M, Gonzalez-Nilo FD, Eyzaguirre J. (2013) Penicillium purpurogenum produces two GH family 43 enzymes with ß-xylosidase activity, one monofunctional and the other bifunctional: biochemical and structural analyses explain the difference. Arch Biochem Biophys. 540(1-2):117-2. Doi: 10.1016/j.abb.2013.10.017
Riquelme MA, Cea LA, Vega JL, Boric MP, Monyer H, Bennett MV, Frank M, Willecke K, Sáez JC. (2013) The ATP Required for Potentiation of Skeletal Muscle Contraction is released via Pannexin Hemichannels. Neuropharmacology. 75:594–603. Doi: 10.1016/j.neuropharm.2013.03.022.
Sáez PJ, Orellana JA, Vega-Riveros N, Figueroa VA, Hernández DE, Castro JF, Klein AD, Jiang JX, Zanlungo S, Sáez JC. (2013) Disruption in connexin-based communication is associated with intracellular ca(2+) signal alterations in astrocytes from niemann-pick type C mice. PLoS One. 8(8):e71361. Doi: 10.1371/journal.pone.0071361
Sáez PJ, Shoji KF, Retamal MA, Harcha PA, Ramírez G, Jiang JX, von Bernhardi R, Sáez JC. (2013) ATP is required and advances cytokine-induced gap junction formation in microglia in vitro. Mediators Inflamm. 2013:216402. Doi: 10.1155/2013/216402
Sáez PJ, Shoji KF, Sáez JC. (2013) Gap Junctions in Antigen-Presenting Cells. In Connexin cell communication channels: roles on the immune system and immunopathology (ed. Oviedo-Orta, Kwak and Evans). Taylor and Francis publisher. pag 61-88. DOI: 10.1201/b14166-14
Soto-Liebe K, López-Cortés XA, Fuentes-Valdes JJ, Stucken K, Gonzalez-Nilo F, Vásquez M. (2013) In silico analysis of putative paralytic shellfish poisoning toxins export proteins in cyanobacteria. PLoS One. 8(2):e55664. Doi: 10.1371/journal.pone.0055664.
Tricarico D, Mele A, Calzolaro S, Cannone G, Camerino MG, Dinardo MM, Latorre R, Conte Camerino D. (2013) Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation. Plos One. 8(7). e69551. Doi: 10.1371/journal.pone.0069551
Vega JL, Subiabre M, Figueroa F, Schalper KA, Osorio L, González J, Sáez JC. (2013) Role of Gap Junctions and Hemichannels in Parasitic Infections. Biomed Res Int. 2013:589130. Doi: 10.1155/2013/589130
Vega-Zuniga T, Medina FS, Fredes F, Zuniga C, Severín D, Palacios AG, Karten HJ, Mpodozis J. (2013). Does nocturnality drive binocular vision? Octodontine rodents as a case study. PlosOne. 8(12):e84199. Doi: 10.1371/journal.pone.0084199
Vergara-Jaque AP, Comer JR, Monsalve LF, Gonzalez-Nilo FD, Sandoval C. (2013) Computationally Efficient Methodology for Atomic-Level Characterization of Dendrimer-Drug Complexes: A Comparison of Amine- and Acetyl-Terminated PAMAM. Journal of Physical Chemistry B. 117(22):6801-13. Doi: 10.1021/jp4000363
Vilos C, Morales FA, Solar PA, Herrera NS, Gonzalez-Nilo FD, Aguayo DA, Mendoza HL, Comer J, Bravo ML, Gonzalez PA, Kato S, Cuello MA, Alonso C, Bravo EJ, Bustamante EI, Owen GI, Velasquez LA. (2013) Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells. Biomaterials. 34(16):4098-108. Doi: 10.1016/j.biomaterials.2013.02.034
Yang S, Megill A, Ardiles AO, Ransom S, Tran T, Koh MT, Lee HK, Gallagher M, Kirkwood A (2013) Integrity Of MGluR-LTD In The Associative/commissural Inputs To CA3 Correlates With Successful Aging In Rats. J Neurosci.33(31):12670-8. Doi: 10.1523/JNEUROSCI.1086-13.2013
Acuña MA, Pérez-Nuñez R, Noriega J, Cárdenas AM, Bacigalupo J, Delgado R, Arriagada C, Segura-Aguilar J, Caviedes R, Caviedes P. (2012) Altered voltage dependent calcium currents in a neuronal cell line derived from the cerebral cortex of a trisomy 16 fetal mouse, an animal model of down syndrome. Neurotoxicity Research. 22(1):59-68.
Aguayo D, Gonzalez-Nilo F, Chipot C. (2012) Insight into the properties of cardiolipin containing bilayers from molecular dynamics simulations, using a hybrid all-atom/united-atom force field. Journal of Chemical Theory and Computation. 8(5):1765-1773.
Ardiles AO, Tapia-Rojas CC, Mandal M, Alexandre F, Kirkwood A, Inestrosa NC & Palacios AG. (2012) Post-synaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease. Proceedings of the National Academy of Science. 109(34):13835-40 .
Avila-Salas, F ; Sandoval, C ; Caballero, J ; Guinez-Molinos, S ; Santos, LS ; Cachau, RE ; Gonzalez-Nilo FD (2012) Study of Interaction Energies between the PAMAM Dendrimer and Nonsteroidal Anti-Inflammatory Drug Using a Distributed Computational Strategy and Experimental Analysis by ESI-MS/MS JOURNAL OF PHYSICAL CHEMISTRY B 116 (7):2031-2039 DOI: 10.1021/jp2069122
Bazáes A. and Schmachtenberg O. (2012) Odorant tuning of olfactory crypt cells from juvenile and adult rainbow trout. Journal of Experimental Biology. 215(Pt 10):1740-8.
Bennett MV, Garré JM, Orellana JA, Bukauskas FF, Nedergaard M, Sáez JC. (2012) Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Research. 1487:3-15.
Braidy N, Munoz P, Palacios AG, Castellano-González G, Inestrosa NC, Chung RS, Sachdev P, Guillemin GJ. (2012) Recent animal models for Alzheimer’s diseases: Clinical implications and basic research. Journal of Neural Transmission. 119(2):173-195.
Cárdenas AM, Ardiles AO, Barraza N, Baéz-Matus X, Caviedes P. (2013) Role of Tau Protein in Neuronal Damage in Alzheimer’s Disease and Down Syndrome. Archives of Medical Research.43(8):645-54.
Cea LA, Riquelme MA, Cisterna BA, Puebla C, Vega JL, Rovegno M, Sáez JC. (2012) Connexin- and annexin-based channels in normal skeletal muscles and their possible role in muscle atrophy. Journal of Membrane Biology. 245(8):423-36.
Contreras GF, Neely A, Alvarez O, Gonzalez C, Latorre R. (2012) Modulation of BK channel voltage gating by different auxiliary β subunits. Proceedings of the National Academy of Sciences. 109(46):18991-6
Cortés C, Eugenin E, Aliaga E, Carreño LJ, Bueno SM, Gonzalez PA, Gayol S, Naranjo D, Noches V, Marassi MP, Rosenthal D, Jadue C, Ibarra P, Keitel C, Wohllk N, Court F, Kalergis AM, Riedel CA. (2012) Hypothyroidism in the adult rat causes incremental changes in brain-derived neurotrophic factor, neuronal and astrocyte apoptosis, gliosis, and deterioration of postsynaptic density. Thyroid. 22(9):951-63.
Couve, E., Osorio, O. and Schmachtenberg O. (2012) Mitochondrial autophagy and lipofuscin accumulation in aging odontoblasts. Journal of Dental Research. 91(7): 1-6.
Dinardo MM, Camerino G, Mele A, Latorre R., Conte Camerino D, Tricarico D. (2012) Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle. Plos One, 7(7):e40235
Eugenin EA, Basilio D, Sáez JC, Orellana JA, Raine CS, Bukauskas F, Bennett MV, Berman JW. (2012) The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. Journal of Neuroimmune Pharmacology. 7(3):499-518.
Fiori MC, Figueroa V, Zoghbi ME, Saez JC, Reuss L, Altenberg GA.(2012) Permeation of calcium through purified connexin 26 hemichannels. Journal of Biological Chemistry. 87(48): 40826-34
Giaume C, Orellana JA, Abudara V, Sáez JC. (2012) Connexin-based channels in astrocytes: how to study their properties. Methods in Molecular Biology. 814:283-303.
Gonzalez C, Báez-Nieto D, Valencia I, Oyarzún I, Rojas P, Naranjo D, and Latorre R. (2012) K channels: function-structural overview. Comprehensive Physiology. 2: 2087-2149.
Gonzalez C Contreras G, Peysler A, Larsson P, Neely A,Latorre R. (2012) Voltage sensor of ion channels and enzymes. Biophysical Reviews. 4(1): 1-15.
Gonzalez W, Riedelsberger J, Morales-Navarro SE, Caballero J, Alzate-Morales JH, Gonzalez-Nilo FD, Dreyer I. (2012) The ph-sensor of the plant K+ uptake channel Kat1 is built of a sensory cloud rather than of single key amino acids. Biochemical Journal. 442(1):57-63.
Harden MV, Pereiro L, Ramialison M, Wittbrodt J, Prasad MK, McCallion AS,Whitlock KE. (2012) Close association of olfactory placode precursors and cranial neural crest cells does not predestine cell mixing. Developmental Dynamics. 241(7):1143-54.
Huang S, Treviño M, He K, Ardiles A, Di Pasquale R, Guo Y, Palacios A, Huganir R, Kirkwood A. (2012) Pull-push neuromodulation of ltp and ltd enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron. 73(3):497-510.
Jara O, Acuña R, García IE, Maripillán J, Figueroa V, Sáez JC, Araya-Secchi R, Lagos CF, Pérez-Acle T, Berthoud VM, Beyer EC, Martínez AD. (2012) Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Molecular Biology of the Cell. 23(17):3299-3311.
Koulakoff A, Mei X, Orellana JA, Sáez JC, Giaume C. (2012) Glial connexin expression and function in the context of Alzheimer’s disease. Biochimica et Biophysica Acta. 1818(8):2048-2057.
Lagos CF, Araya-Secchi R, Thomas P, Pérez-Acle T, Tapia RA, Salas CO. (2012) Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione. Journal of Molecular Modeling. 18(5):2055-64.
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