The CINV approaches different aspects of a fundamental scientific question; how does the nervous system respond to the different sensory stimuli in the healthy and the diseased brain? This question is addressed by the different research lines present in the center, studying from the functioning of proteins that capture signals from the outside world to the wiring and connectivity of the different neural networks.
Line 1: Structure and function of molecular sensors
This research line focuses on studying how the external environment influences channels present on the cell membrane that open or close depending on the external stimuli. In mammals, these channel determine processes as relevant as hormone secretion and neurotransmitters sensory transduction and muscle and nerve excitation.
Line 2: Cellular signaling
This line studies the molecular mechanisms that allow cell signaling, an essential process for the adequate communication between cells and that results crucial for the correct functioning of the system within the optimal parameters of signal transmission, both in time and in intensity.
Line 3: Genetics and development of the Nervous System
Researchers in this line study the development of the nervous sytem using olfaction as a model and more specifically, how environmental factors can modify gene expression, demonstrating that during early development, environmental odorants alter the genetic expression of olfactory receptors.
Line 4: Systems and circuits Neuroscience
In this line the main interest is to understand how stimuli perceived-arriving from the external world are transformed by our neuronal circuits to produce behaviors (and translated into behaviors).
Line 5: Computational biology and molecular simulation
Researcher in this line study the processes of intercellular communication, ionic channel activation, neuronal dynamics and neural networks using a combination of modeling and experimentation, …