{"id":24120,"date":"2018-04-26T18:46:07","date_gmt":"2018-04-26T18:46:07","guid":{"rendered":"http:\/\/cinv.uv.cl\/publicaciones-4\/"},"modified":"2026-03-24T15:56:54","modified_gmt":"2026-03-24T15:56:54","slug":"papers","status":"publish","type":"page","link":"https:\/\/cinv.uv.cl\/en\/papers\/","title":{"rendered":"Publicaciones cient\u00edficas"},"content":{"rendered":"

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\u00a0 \u00a0Publications<\/span><\/h1>\n
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Acosta ML, Zhang SX, Palacios AG<\/a><\/strong> (2026) Blood\u2013retinal biomarker integration for precision prevention of Alzheimer\u2019s disease: Lessons from retinal aging and the unfolded protein response. Neural Regen Res. doi: 10.4103\/NRR.NRR-D-25-01517<\/li>\n
Caro JC, Bucchi C, Ponce N, Villena J, Palacios-Mu\u00f1oz A<\/strong><\/a>, Garc\u00eda IE<\/strong><\/a>. (2025) Biological matrices promote odontoblastic markers expression in stem cells from apical papilla: an in vitro study. J Endod. S0099-2399(26)00130-5. doi: 10.1016\/j.joen.2026.03.006. Online ahead of print<\/li>\n
Echeverr\u00eda F, Pe\u00f1a-Pichicoi A, Fernandez M, Carrasquel-Ursulaez W, Castillo JP<\/strong><\/a>, Alvarez<\/strong> O, Latorre R<\/strong><\/a>. (2026) Tuning the gate and the gear: The LRRC26 (\u03b31) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel. Proc Natl Acad Sci U S A. 123(8):e2526651123. doi: 10.1073\/pnas.2526651123<\/li>\n
Garc\u00eda A, M\u00e1rquez-Miranda V, Bravo-Acu\u00f1a N, Araya-Duran I, Rojas M, Palacios-Prado N, O’Brien J, Gonzalez-Nilo FD<\/strong><\/a>, S\u00e1ez JC<\/a><\/strong>. (2026) Influence of extracellular magnesium ions on the functional state and biophysical and structural properties of connexin36 hemichannels. Proc Natl Acad Sci U S A. 123(12):e2538150123. doi: 10.1073\/pnas.2538150123<\/li>\n
Garc\u00eda IE<\/strong><\/a>, Contreras JE. (2025) Decoding Connexin Hemichannels: Structure, Function, and Regulatory Mechanisms. Annu Rev Physiol. 88:73-98 doi: 10.1146\/annurev-physiol-050724-010008.<\/li>\n
Gonzalez-Sanabria N, Contreras GF, Rojas M, Duarte Y<\/strong><\/a>, Gonzalez-Nilo FD<\/strong><\/a>, Perozo E and Latorre R<\/strong><\/a> (2026) The BK channel-NS1619 agonist complex reveals molecular insights into allosteric activation gating. Proc Natl Acad Sci U S A 123(5): e2507707123 doi: 10.1073\/pnas.2507707123<\/li>\n
Grubsic C, C\u00e9spedes R, Tapia F, Schmachtenberg O<\/strong><\/a>. (2025) Myopia pathogenesis and vasoactive intestinal peptide: Molecular mechanisms, experimental models, and clinical implications. Exp Eye Res. 263:110810. doi: 10.1016\/j.exer.2025.110810<\/li>\n
Maureira D, Rubilar C, L\u00f3pez J, Santander P, Moldenhauer H, Silva I, Cruz P, Riquelme D, Baeza J, Gonz\u00e1lez W, Orio P<\/a><\/strong>, Servili E, Troncoso M, Leiva-Salcedo E, Cerda O. (2026) A KCNC1 variant linked to Rett syndrome disrupts ER to Golgi trafficking of Kv3.1 channel. Proc Natl Acad Sci U S A. 123(11):e2424514123. doi: 10.1073\/pnas.2424514123<\/li>\n
Mellado G, Saavedra J, Lincolao-Venegas I, Garate JA<\/a>, Neely A<\/a><\/strong>. (2026) Multiscale molecular dynamics simulations identify SNX-482\/KV4.3 binding determinants. Biophys J. 125(2):616-628. doi: 10.1016\/j.bpj.2025.10.029<\/li>\n
Meza RC, Morales-Weil K, Ancat\u00e9n-Gonz\u00e1lez C, Escobar AP, Alcaino A, Sanguinetti N, Delpire E, Moya PR<\/strong><\/a>, Chiu CQ, Fuenzalida M, Ch\u00e1vez AE<\/strong><\/a>. (2026) Serotonin-endocannabinoid crosstalk selectively regulates inhibitory GABAergic inputs in the medial prefrontal cortex. Neuropsychopharmacology. 2026 Feb 11. doi: 10.1038\/s41386-026-02364-8. Online ahead of print<\/li>\n
Pan J, Toro CA, Chow C, Duarte Y, S\u00e1ez JC<\/a><\/strong>, Cardozo CP, Zhao W. (2026) Oral administration of boldine reduces neuropathic pain After spared nerve injury in female mice. PAIN Reports 11(1):e1386. doi: 10.1097\/PR9.0000000000001386<\/li>\n
Pinto-Anwandter BI, Bezanilla F<\/strong><\/a>. (2025) Quantifying Activation Delay and the Cole-More shift via Current Derivatives. Biophys J. 125(3):688-696. doi: 10.1016\/j.bpj.2025.12.010<\/li>\n
Sabadini G, Palacios-Mu\u00f1oz A<\/strong><\/a>, Garc\u00eda IE<\/strong><\/a>, Romero-Parra J, Moraga D, Soto M, Vega-Mu\u00f1oz A, Contreras-Barraza N, Salazar-Sep\u00falveda G, Mella J, Mellado M. (2026) Mapping Global Research Trends on Autism Spectrum Disorder: A Bibliometric Analysis of Pharmacology and Pharmacy Studies. Pharmaceuticals (Basel). 19(1):102. doi: 10.3390\/ph19010102<\/li>\n
Storch EA, McCarty RJ, Zehavi M, Ahmad M, Cruz VZ, Berrones D, Mu\u00f1oz JS, Obando D, Rodriguez Barajas S, Frederick RM, Anderberg JL, Moore HC, Ochoa-Panaifo ME, Martinez Mallen MC, Onyeka OC, Wiese AD, Sagarnaga MN, McGuire JF, Ferr\u00e3o YA; Latin American Trans-Ancestry INitiative for OCD genomics (LATINO); Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (GTTOC); Goodman WK, Crowley JJ. (2026) Predictive validity of the Obsessive-Compulsive Inventory-4 and Florida Obsessive-Compulsive Inventory-II severity scale. J Psychiatr Res. 194:349-360. doi: 10.1016\/j.jpsychires.2025.12.011<\/li>\n
Troncoso F, Sandoval H, Escudero-Guevara E, Nualart F, Ram\u00edrez E, Sanda\u00f1a P, Ek J, Herrock O, Merceron D, Ardiles \u00c1O<\/strong><\/a>, Vatish M, Acurio J, Escudero C. (2026) Disrupted brain angiogenesis and blood-brain barrier function underlie cognitive deficits in offspring of preeclampsia-like pregnancies. J Physiol. . doi: 10.1113\/JP289605. Online ahead of print<\/li>\n
V\u00e1squez W, Urrutia C, L\u00f3pez X, Cea LA, Vega JL, Berthoud VM, S\u00e1ez JC<\/a><\/strong>. (2026) High Activity of Hemichannels Permeable to Calcium Ions Leads to ROS Generation and Reduced Cell Viability. Int J Mol Sci. 27(4):1699. doi: 10.3390\/ijms27041699<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n
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Ancat\u00e9n-Gonz\u00e1lez C, Meza RC, Gonzalez-Sanabria N, Segura I, Alcaino A, Pe\u00f1a-Pichicoi A, Latorre R<\/a><\/strong>, Chiu CQ<\/a><\/strong>, Ch\u00e1vez AE<\/a><\/strong>. (2025) BK channels mediate a presynaptic form of mGluR-LTD in the neonatal hippocampus. Proc Natl Acad Sci U S A. 122(2):e2411506122. doi: 10.1073\/pnas.2411506122.<\/li>\n
Ardiles NM, Tapia-Cuevas V, Estay SF, Alcaino A, Vel\u00e1squez VB, Sotomayor-Z\u00e1rate R, Ch\u00e1vez AE<\/a><\/strong>. Moya PR<\/strong><\/a>. (2024). Increased forebrain EAAT3 expression confers resilience to chronic stress. J. Neurochem 169(1):e16216. doi: 10.1111\/jnc.16216<\/li>\n
Balboa E, Saavedra F, Cea LA, Vargas AA, Regueira T, S\u00e1ez JC<\/strong><\/a>. (2025) Connexin hemichannels and early atrophic signaling in muscle during sepsis. Front Physiol. 16:1514769. doi: 10.3389\/fphys.2025.1514769<\/li>\n
Coca A, L\u00f3pez S, \u00d3rdenes P, Sep\u00falveda V, Cuevas D, Villarroel A, \u00c1lvarez-Indo J, Burgos PV, Tarife\u00f1o E, Elizondo-Vega R, Garc\u00eda-Robles MA<\/a><\/strong>. (2025 Knocking down the neuronal lactate transporter MCT2 in the arcuate nucleus of female rats increases food intake and body weight. Sci Rep. 15(1):7497. doi: 10.1038\/s41598-025-90513-2<\/li>\n
Contreras GF, Shen R, Latorre R<\/a><\/strong>, Perozo E. (2025) Structural basis of voltage-dependent gating in BK channels. Nat Commun. 16(1):5846. doi: 10.1038\/s41467-025-60639-y<\/li>\n
Coronel-Oliveros C, Migeot J, Lehue F, Amoruso L, Kowalczyk-Gr\u0119bska N, Jakubowska N, Mandke KN, Seabra JP, Orio P<\/a><\/strong>, Campbell D, Gonzalez-Gomez R, Prado P, Cuadros J, Tagliazucchi E, Cruzat J, Legaz A, Medel V, Hernandez H, Fittipaldi S, Altschuler F, Moguilner S, Baez S, Santamaria-Garcia H, Gonz\u00e1lez-Hern\u00e1ndez A, Bonilla-Santos J, G\u00fcntekin B, Babiloni C, Abasolo D, Di Caterina G, Yener GG, Escudero J, Ochoa-G\u00f3mez JF, Soto-A\u00f1ari M, Bruno MA, Valdes-Sosa PA, Anghinah R, Gonzalez-Montealegre RA, Clark RA, Garc\u00eda AM, Kaltwasser L, Sch\u00fcrmann M, Meier JM, Brzezicka A, Whelan R, Lawlor B, Robertson IH, Bailey C, Melloni L, Sajnani N, Ibanez A. (2025) Creative experiences and brain clocks. Nat Commun. 16(1):8336. doi: 10.1038\/s41467-025-64173-9<\/li>\n
Coronel-Oliveros C, Moguilner S, Hernandez H, Cruzat J, Baez S, Medel V, Cuadros J, Santamaria-Garcia H, Valdes-Sosa PA, Lopera F, Ochoa-G\u00f3mez JF, Gonz\u00e1lez- Hern\u00e1ndez A, Bonilla-Santos J, Gonzalez-Montealegre RA, Akt\u00fcrk T, Y\u0131ld\u0131r\u0131m E, Anghinah R, Legaz A, Fittipaldi Sol, Yener GG, Escudero J, Babiloni C, Lopez S, Whelan R, Fern\u00e1ndez A, Huepe D, Di Caterina G, Soto-A\u00f1ari M, Gonzalez-Gomez R, Herrera E, Abasolo D, Kilborn K, Rubido N, Clark R, Herzog R, Yerlikaya D, G\u00fcntekin Ba, Deco G, Prado P, Parra MA, Orio P<\/a><\/strong>, Tagliazucchi E, Lawlor B, Ibanez A (2025) Diversity-sensitive brain clocks linked to biophysical mechanisms in aging and dementia. Nat Mental Health. 3: 1214-1229. doi: 10.1038\/s44220-025-00502-7<\/li>\n
De Giorgis D, Mellado G, Garate JA<\/a>, Neely A <\/a><\/strong>(2025) Regulation of voltage-sensing structures of CaV1.2 calcium channel by the auxiliary \u03b23-subunit. J Gen Physiol. 158(1):e202413739. doi: 10.1085\/jgp.202413739.<\/li>\n
Di Berardino C, Estay SF, Alcaino A, Ch\u00e1vez AE<\/a><\/strong>. (2025) Serotonin regulates in a cell-type specific manner light-evoked response and synaptic activity in mouse retinal ganglion cells. Biol Res. 58(1):11. doi: 10.1186\/s40659-025-00594-6<\/li>\n
Flores-Mu\u00f1oz C, Labra\u00f1a-Allende M, Mattar-Araos M, Gomez-Soto B, Silva-Guzman J, Prado-Vega L, Arriagada-D\u00edaz J, Guerra-Fern\u00e1ndez MJ, Bevilacqua JA, Bitoun M, C\u00e1rdenas AM<\/strong><\/a>, Ardiles AO<\/strong><\/a>, Gonzalez-Jamett AM<\/strong><\/a>. (2025) The synaptic availability of GluA1 is reduced in hippocampal neurons of a murine model of dynamin-2 linked autosomal dominant centronuclear myopathy. Sci Prog. 108(2):368504251332815. doi: 10.1177\/00368504251332815<\/li>\n
Garc\u00eda-Rodr\u00edguez C, Flores-Mu\u00f1oz C, Fern\u00e1ndez P, Escobar M, Ardiles AO<\/strong><\/a>, C\u00e1rdenas AM<\/a>, S\u00e1ez JC<\/a><\/strong>. (2025) Boldo leaves reduce seizures, neuroinflammation, and hemichannel activity in a murine model of chronic epilepsy. Biol Res. 58(1):72. doi: 10.1186\/s40659-025-00647-w<\/li>\n
Gonz\u00e1lez-Madrid E, Rangel-Ram\u00edrez MA, Opazo MC, Espinoza SA, Elgueta D, Cancino GI, Mery E, Ardiles AO<\/strong><\/a>, Duarte LF, Soto JA, Carre\u00f1o LJ, Simon F, Bueno SM, Gonz\u00e1lez PA, Kalergis AM, Riedel CA. (2025) Gestational hypothyroxinemia causes an inflammatory environment at maternal-fetal tissues and fetal brain with impaired hippocampal dendritic spine maturation in the offspring. Sci Rep.15(1):42160. doi: 10.1038\/s41598-025-26206-7<\/li>\n
Illanes-Gonz\u00e1lez J, Flores-Mu\u00f1oz C, Vitureira N, Ardiles A\u00c1O<\/a><\/strong> (2025) Pannexin 1 channels: A Bridge Between Synaptic Plasticity and Learning and Memory Processes. Neurosci Biobehav Rev. 174:106173. doi: 10.1016\/j.neubiorev.2025.106173.<\/li>\n
Lehue F, Coronel-Oliveros C, Medel V, Liebe T, Kaufmann J, Orellana S, Becerra D, Tagliazucchi E, Orio P<\/strong><\/a>. (2025) Noradrenaline and acetylcholine shape functional connectivity organization of NREM substages: An empirical and simulation study. PLoS Comput Biol. 21(10):e1012852. doi: 10.1371\/journal.pcbi.1012852<\/li>\n
Liu Y, Bassetto C, Contreras GF, Perozo E, Bezanilla F<\/a><\/strong>. (2025) Closed state structure of the pore revealed by uncoupled Shaker K+ channel. Nat Commun. 16(1):10180. doi: 10.1038\/s41467-025-65124-0<\/li>\n
Liu Y, Bezanilla F<\/a><\/strong>. (2025) A sodium channel mutant removes fast inactivation with the inactivation particle bound. J Gen Physiol. 157(1):e202413667. doi: 10.1085\/jgp.202413667<\/li>\n
Liu Y, Galpin JD, Ahern CA, Bezanilla F<\/a><\/strong>. (2025) Molecular basis of sodium channel inactivation. Nat Commun. 16(1):10565. doi: 10.1038\/s41467-025-65587-1<\/li>\n
Olivares J, Orio P, Sad\u00edlek V, Schmachtenberg O<\/strong><\/a>, Canales-Johnson A. (2025) Odorant representations indicate nonlinear processing across the olfactory system. Cereb Cortex. 35(5):bhaf112. doi: 10.1093\/cercor\/bhaf112<\/li>\n
Palacios AG<\/a><\/strong>, Zhang SX, Acosta ML. (2025). Diabetic Retinopathy and Alzheimer\u2019s Disease: Convergence of the Unfolded Protein Response in Neurodegeneration. Alzheimers Dement. 21(8):e70497. doi: 10.1002\/alz.70497<\/li>\n
Palma-Espinosa J, Orellana-Villota S, Coronel-Oliveros C, Maidana JP, Orio P<\/strong><\/a>. (2025) The balance between integration and segregation drives network dynamics maximizing multistability and metastability. Sci Rep. 15(1):18811. doi: 10.1038\/s41598-025-01612-z<\/li>\n
Pinciotti CM, Avery J, Zhang C,,,, Moya P<\/strong><\/a>. \u2026., et al (2025) Benchmarking empirical severity for the Yale-Brown Obsessive Compulsive Scale-Second Edition. J Affect Disord. 119719. doi: 10.1016\/j.jad.2025.119719<\/li>\n
Pinto-Anwandter BI, Bassetto CAZ Jr, Latorre R<\/a><\/strong>, Bezanilla F<\/strong><\/a>. (2025) Energy landscape of a Kv channel revealed by temperature steps while perturbing its electromechanical coupling. Nat Commun. 16(1):3379. doi: 10.1038\/s41467-025-58443-9<\/li>\n
S\u00e1ez JC<\/strong><\/a>, Ocaranza FJ, Prieto-Villalobos J, Orellana JA. (2025) Connexin and Pannexin Hemichannels: Broad-Spectrum Players in Neuroinflammatory Signaling. J Neurochem. 169(9):e70237. doi: 10.1111\/jnc.70237<\/li>\n
Salgado F, Sbarbaro C, Leal M, Galdames F, D\u00edaz-Franulic I, Cantero P, Durango D, Forero-Doria O, V\u00e1zquez P, Due\u00f1as F, Duarte Y<\/a><\/strong> (2025) Physicochemical properties and gastrointestinal release of Chilean endemic berry extracts via biopolymer encapsulation. LWT – Food Sci Technol. 237: 118693. Doi: 10.1016\/j.lwt.2025.118693<\/li>\n
Salgado M, Sep\u00falveda-Arriagada V, Konar-Ni\u00e9 M, Garc\u00eda-Robles MA<\/a><\/strong>, S\u00e1ez JC<\/strong><\/a>. (2025) Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3\/Ca2+\/CaMKII\/pannexin 1-dependent signaling. Theranostics. 15(6):2470-2486. doi: 10.7150\/thno.100687<\/li>\n
Santander O, Arredondo SB, Garc\u00eda-Rojas F, Estay SF, Belforte JE, Ch\u00e1vez AE<\/a><\/strong>, Varela-Nallar L, Fuenzalida M. (2025) Ketamine administration during adolescence impairs synaptic integration and inhibitory synaptic transmission in the adult dentate gyrus. Prog Neurobiol. 246:102718. doi: 10.1016\/j.pneurobio.2025.102718<\/li>\n
Scholz-Carlson E, Iyer AR, Nern A, Ewer J<\/a><\/strong>, Fernandez MP. (2025) Synaptic targets of circadian clock neurons influence core clock parameters. Sci Adv. 11(36):eadw4666. doi: 10.1126\/sciadv.adw4666<\/li>\n
Serey M, Retamales E, Iba\u00f1ez G, Riadi G, Orio P<\/strong><\/a>, Castillo JP, Calixto A<\/strong><\/a>. (2025) Interspecies relationships of natural amoebae and bacteria with C. elegans create environments propitious for multigenerational diapause. mSystems. 10(4):e0156624. doi: 10.1128\/msystems.01566-24<\/li>\n
Silva V, Scott R, Guajardo P, Luan H, Herzog R, White BH, Ewer J<\/a><\/strong>. (2025) Characterization of eclosion hormone receptor function reveals differential hormonal control of ecdysis during Drosophila development. PLoS Genet. 21(8):e1011672. doi: 10.1371\/journal.pgen.1011672<\/li>\n
Storch EA, Cheng JS, Higham M, Mu\u00f1oz JS, Cruz VZ, Berrones D, Obando DP, Anderberg JL, Frederick RM, Tapia-Cuevas V, Mu\u00f1oz MC, Villar CU, Moya PR<\/strong><\/a>, Ochoa-Panaifo ME, Mallen MCM, Wiese AD, Pinciotti CM, Sagarnaga MN, McGuire JF, Onyeka OC, Moyano MB; Latin American Trans-Ancestry INitiative for OCD genomics (LATINO); Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (GTTOC); Goodman WK, Crowley JJ. (2025) Psychometric properties of the Spanish Yale-Brown Obsessive-Compulsive Scale – Second Edition. Psychiatry Res. 348:116456. doi: 10.1016\/j.psychres.2025.116456<\/li>\n
Tognarelli J, Moya PR<\/strong><\/a>, Gonz\u00e1lez CR, Collao-Ferrada X. (2025) Global distribution and impact of knockdown resistance mutations in Aedes aegypti on pyrethroid resistance. Parasit Vectors. 18(1):382. doi: 10.1186\/s13071-025-06817-9<\/li>\n
Toro CA, Zhao W, Garcia Silva P, Retamal-Santib\u00e1\u00f1ez D, Rojas F, Pan J, Johnson N, Duarte Y<\/a><\/strong>, Cardozo CP, S\u00e1ez JC<\/strong><\/a>, van Zundert B. (2025) Boldine as a neuroprotective agent against motor neuron degeneration in models of amyotrophic lateral sclerosis. Front Cell Neurosci. 19:1640590. doi: 10.3389\/fncel.2025.1640590<\/li>\n
van Veggel L, Schepers M, Tiane A, Kumar V, Willems E, Rombaut B, Noordijk J, Vangansewinkel T, Li A, Wolfs E, Ozcan B, Nouboers E, Moya PR<\/strong><\/a>, Sauer DB, Dili\u00ebn H, Hellings N, Schreiber R, Vanmierlo T. (2025) EAAT3 modulation: A potential novel avenue towards remyelination in multiple sclerosis. Biomed Pharmacother. 186:117960. doi: 10.1016\/j.biopha.2025.117960<\/li>\n
V\u00e1squez W, Toro CA, Cardozo CP, Cea LA, S\u00e1ez JC<\/strong><\/a>. (2025) Pathophysiological role of connexin and pannexin hemichannels in neuromuscular disorders. J Physiol. 603(15):4213-4235. doi: 10.1113\/JP286173<\/li>\n
V\u00e1squez W, Troncoso F, Lira A, Escudero C, S\u00e1ez JC<\/strong><\/a> (2025) Boldo Restores Vascularization and Reduces Skeletal Muscle Inflammation in Symptomatic Mice with Dysferlinopathy. Int J Mol Sci 26 (20), 9945 doi: 10.3390\/ijms26209945<\/li>\n
Wang WA, Ferrada E<\/strong><\/a>, Klimek C, Osthushenrich T, MacNamara A, Wiedmer T, Superti-Furga G. (2025) Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5 Sci Adv.;11(26):eadx3011. doi: 10.1126\/sciadv.adx3011<\/li>\n
Wang WA, Garofoli A, Ferrada E<\/strong><\/a>, Klimek C, Steurer B, Ingles-Prieto A, Osthushenrich T, MacNamara A, Malarstig A, Wiedmer T, Superti-Furga G. (2025) Human genetic variants in SLC39A8 impact uptake and steady-state metal levels within the cell. Life Sci Alliance. 8(4):e202403028. doi: 10.26508\/lsa.202403028<\/li>\n<\/ol>\n
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Ahumada-Marchant C, Ancat\u00e9n-Gonzalez C, Haensgen H, Brauer B, Merino-Veliz N, Droste R, Arancibia F, Horvitz HR, Constantine-Paton M, Arriagada G, Ch\u00e1vez AE<\/a><\/strong>, Bustos FJ. (2024) Deletion of VPS50 protein in mouse brain impairs synaptic function and behavior. BMC Biol. 22(1):142. doi: 10.1186\/s12915-024-01940-y<\/li>\n
Amaya-Rodriguez CA, Carvajal-Zamorano K, Bustos D, Alegr\u00eda-Arcos M, Castillo K<\/strong><\/a>. (2024) A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel. Front Pharmacol. 14:1251061. doi: 10.3389\/fphar.2023.1251061<\/li>\n
Asencio C, V\u00e9liz L, Flores-Fa\u00fandez E, Az\u00f3car L, Echeverr\u00eda CE, Torres-Estay V, Orellana V, Ram\u00edrez-Santelices C, Sotomayor P, Cancino J, Kerr B, Fernandez-Olivares A, Retamal MA, S\u00e1ez JC<\/strong><\/a>, Godoy AS. (2024) Lack of canonical activities of connexins in highly aggressive human prostate cancer cells. Biol Res. 57(1):97. doi: 10.1186\/s40659-024-00565-3<\/li>\n
Bassetto CAZ Jr, Pfeffermann J, Yadav R, Strassgschwandtner S, Glasnov T, Bezanilla F<\/strong><\/a>, Pohl P. (2024) Photolipid excitation triggers depolarizing optocapacitive currents and action potentials. Nat Commun. 15(1):1139. doi: 10.1038\/s41467-024-45403-y<\/li>\n
Bayon\u00e9s L, Guerra-Fern\u00e1ndez MJ, Figueroa-Cares C, Gallo LI, Alfonso-Bueno S, Caspe O, Canal MP, B\u00e1ez-Matus X, Gonz\u00e1lez-Jamett A<\/a><\/strong>, C\u00e1rdenas AM<\/strong><\/a>, Marengo FD. (2024) Dynamin-2 mutations linked to neonatal-onset centronuclear myopathy impair exocytosis and endocytosis in adrenal chromaffin cells. J Neurochem. 168(9):3268-3283. doi: 10.1111\/jnc.16194<\/li>\n
Brauer B, Ancat\u00e9n-Gonz\u00e1lez C, Ahumada-Marchant C, Meza RC, Merino-Veliz N, Nardocci G, Varela-Nallar L, Arriagada G, Ch\u00e1vez AE<\/a><\/strong>, Bustos FJ. (2024) Impact of KDM6B mosaic brain knockout on synaptic function and behavior. Sci Rep. 14(1):20416. doi: 10.1038\/s41598-024-70728-5<\/li>\n
Calbiague-Garcia VC, Chen Y, C\u00e1diz B, Tapia F, Paquet-Durand F, Schmachtenberg O<\/strong><\/a>. (2024) Extracellular lactate as an alternative energy source for retinal bipolar cells. J Biol Chem. 300(4):106794. doi: 10.1016\/j.jbc.2024.106794<\/li>\n
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[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2023″ tab_id=”2023″][vc_column_text 0=””]<\/p>\n
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[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2020″ tab_id=”2020″][vc_column_text 0=””]<\/p>\n
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[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2019″ tab_id=”2019″][vc_column_text 0=””]<\/p>\n
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[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2018″ tab_id=”2018″][vc_column_text 0=””]<\/p>\n
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Acevedo W, Capitaine C, Rodr\u00edguez R, Araya\u2010Dur\u00e1n I, Gonzalez-Nilo F<\/strong><\/a>, P\u00e9rez\u2010Correa JR, Agosin E (2018)\u00a0Selecting optimal mixtures of natural sweeteners for carbonated soft drinks through multi\u2010objective decision modeling and sensory validation.\u00a0Journal of Sensory Studies. 33(6): e12466. doi: 10.1111\/joss.12466<\/li>\n
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Carrasquel-Ursulaez W, Alvarez O<\/strong>, Bezanilla F<\/strong><\/a>, Latorre R<\/strong><\/a> (2018) Determination of the Stoichiometry between \u03b1- and \u03b31 Subunits of the BK Channel Using LRET. Biophys J. 114(11):2493-2497. doi: 10.1016\/j.bpj.2018.04.008<\/li>\n
Carrasquel-Ursulaez W, Lorenzo Y, Echeverria F and Latorre R<\/strong><\/a> 2018. Large conductance potassium channels in the nervous system.\u00a0 In: The Oxford Handbook of Neuronal Ion Channels, Oxford Handbooks Online, UK. Online publication date: April 2018. DOI: 10.1093\/oxfordhb\/9780190669164.013.11.<\/li>\n
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Vilches F, Ravanal MC, Bravo-Moraga F, Gonzalez-Nilo D<\/a><\/strong>, Eyzaguirre J. (2018) Penicillium purpurogenum produces a novel endo-1,5-arabinanase, active on debranched arabinan, short arabinooligosaccharides and on the artificial substrate p-nitrophenyl arabinofuranoside. Carbohydr Res. 455:106-113. doi: 10.1016\/j.carres.2017.11.014.<\/li>\n
Wellmann M, \u00c1lvarez-Ferradas C, Maturana CJ, S\u00e1ez JC<\/strong><\/a>, Bonansco C. (2018)\u00a0\u00a0Astroglial Ca2+-Dependent Hyperexcitability Requires P2Y1 Purinergic Receptors and Pannexin-1 Channel Activation in a Chronic Model of Epilepsy. Front Cell Neurosci. 12:446. doi: 10.3389\/fncel.2018.00446<\/li>\n
Xu K, Maidana JP, Castro S and Orio P<\/strong><\/a>\u00a0<\/strong>(2018)\u00a0Synchronization transition in\u00a0neuronal networks composed of\u00a0chaotic or non-chaotic oscillators. Scientific Reports. 8(1):8370. doi: 10.1038\/s41598-018-26730-9<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2017″ tab_id=”2017″][vc_column_text 0=””]<\/p>\n
\n
Agurto A, Vielma AH, Cadiz B, Couve E, Schmachtenberg O<\/strong><\/a>. (2017) NO signaling in retinal bipolar cells. Exp Eye Res. 161:30-35. doi: 10.1016\/j.exer.2017.05.013<\/li>\n
Ahumada C, Bahamondes C, Cerda CA, Silva RA, Cruz G, Moya PR<\/strong><\/a>, Sotomayor-Z\u00e1rate R, Renard GM. (2017) Amphetamine treatment affects the extra-hypothalamic vasopressinergic system in a sex- and nucleus-dependent manner. J Neuroendocrinol. 29(4). doi: 10.1111\/jne.12465<\/li>\n
Alvarez O, Carmona E, Latorre R<\/strong><\/a> & Gonzalez C<\/strong><\/a>. (2018) A Glimpse into the Permeation Pathway of the Voltage-Dependent Proton Channel (Hv1). Comments on CrossTalk 33: Proton permeation through HV1 requires\/does not require transient protonation of a conserved aspartate in the S1 transmembrane helix.\u00a0Journal of Physiology. https:\/\/physoc.onlinelibrary.wiley.com\/action\/downloadSupplement?doi=10.1113%2FJP274495&attachmentId=2213602375<\/li>\n
Alvarez O<\/strong> and Latorre R<\/strong><\/a>. (2017)\u00a0 The enduring legacy of the “constant-field equation” in membrane ion transport\u00a0J Gen Physiol. 149(10):911-920. doi: 10.1085\/jgp.201711839<\/li>\n
Ardiles AO, Grabrucker AM, Scholl FG, Rudenko G, Borsello T. (2017).\u00a0Molecular and Cellular Mechanisms of Synaptopathies. \u00a0Neural Plast. 2017:2643943. doi: 10.1155\/2017\/2643943<\/li>\n
Asuaje A, Smaldini P, Mart\u00edn P, Enrique N, Orlowski A, Aiello EA, Gonzalez Le\u00f3n C<\/a>,<\/strong> Docena G, Milesi V. (2017) The inhibition of voltage-gated H+\u00a0channel (HVCN1) induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis. Pflugers Arch. 469(2):251-261. doi: 10.1007\/s00424-016-1928-<\/li>\n
Berna-Erro A, Izquierdo-Serra M, Sep\u00falveda RV, Rubio-Moscardo F, Do\u00f1ate-Maci\u00e1n P, Serra SA, Carrillo-Garcia J, Per\u00e1lvarez-Mar\u00edn A, Gonzalez-Nilo F<\/a><\/strong>, Fern\u00e1ndez-Fern\u00e1ndez JM, Valverde MA (2017)\u00a0Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.\u00a0Sci Rep. 7(1):10522. doi: 10.1038\/s41598-017-11274-1<\/li>\n
Calbiague VM, Olivares J, Olivares E, Schmachtenberg O<\/strong><\/a>\u00a0(2017) The Chilean Recluse Spider (Araneae: Sicariidae) Displays Behavioral Responses to Conspecific Odors, but Not to Several General Odorants.\u00a0J Med Entomol. 54(5):1435-1439. doi: 10.1093\/jme\/tjx101<\/li>\n
C\u00e1rdenas AM<\/a><\/strong>, Fern\u00e1ndez-Olivares P, Diaz-Franulic I<\/a><\/strong>, Gonz\u00e1lez-Jamett AM<\/strong><\/a>, Shimahara T, Segura-Aguilar J, Caviedes R, Caviedes P. (2017) Knockdown of Myo-Inositol Transporter SMIT1 Normalizes Cholinergic and Glutamatergic Function in an Immortalized Cell Line Established from the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Human Trisomy 21 (Down Syndrome). Neurotox Res.\u00a032(4):614-623. doi: 10.1007\/s12640-017-9775-0<\/li>\n
Castillo K, Diaz-Franulic I<\/a><\/strong>, Canan J, Gonzalez-Nilo F<\/a><\/strong>\u00a0and Latorre R<\/strong><\/a>.<\/a> (2017) Thermally-activated TRP channels: Molecular sensors for temperature detection. Physical Biology. 15(2):021001. doi: 10.1088\/1478-3975\/aa9a6f.<\/li>\n
Castillo K, Valenzuela V, O\u00f1ate M and Hetz C. 2016. A molecular reporter for monitoring autophagic flux in nervous system in vivo. Methods in Enzymology 588:109-131. doi: 10.1016\/bs.mie.2016.09.077<\/li>\n
Castro-Severyn J, Remonsellez F, Valenzuela SL, Salinas C, Fortt J, Aguilar P, Pardo-Est\u00e9 C, Dorador C, Quatrini R, Molina F, Aguayo D, Castro-Nallar E, Saavedra CP. (2017) Comparative Genomics Analysis of a New Exiguobacterium Strain from Salar de Huasco Reveals a Repertoire of Stress-Related Genes and Arsenic Resistance. Front Microbiol. 8:456. doi: 10.3389\/fmicb.2017.00456.<\/li>\n
Charv\u00e9riat M, Naus CC, Leybaert L, S\u00e1ez JC<\/a>,<\/strong> Giaume C. (2017) Connexin-Dependent Neuroglial Networking as a New Therapeutic Target. Front Cell Neurosci. 11:174. doi: 10.3389\/fncel.2017.00174. eCollection 2017. Review.<\/li>\n
Couve E, Lovera M, Suzuki K, Schmachtenberg O<\/strong><\/a>. (2017) Schwann cell phenotypes in the aging human dental pulp. J Dental Res. 97(3):347-355. doi: 10.1177\/002203451773396<\/li>\n
Duran-Aniotz C, Cornejo V, Espinoza S, Ardiles AO, Medinas D, Salazar C, Foley A, Gajardo I, Thielen P, Iwawaki T, Scheper W, Soto C, Palacios AG<\/strong><\/a>, Hoozemans J, Hetz C. (2017) IRE1 Signaling exacerbates Alzheimer’s\u00a0disease pathogenesis. Acta Neuropathologica. doi: 10.1007\/s00401-017-1694-x<\/li>\n
Escobar AP (2017)\u00a0The Role of Kappa Opioid Receptors in Glutamate Input Selection in the Ventral Striatum.\u00a0J Neurosci. 2017 Nov 15;37(46):11072-11073 Doi: 10.1523\/JNEUROSCI.2381-17.2017<\/li>\n
Espinosa N, Alonso A, Morales C, Espinosa P,\u00a0Ch\u00e1vez AE<\/a>,<\/strong> Fuentealba P. (2017)\u00a0Basal Forebrain Gating by Somatostatin Neurons Drives Prefrontal Cortical Activity. Cereb cortex. 29(1):42-53. doi: 10.1093\/cercor\/bhx302<\/li>\n
Gajardo-G\u00f3mez R, Labra VC, Maturana CJ, Shoji KF, Santiba\u00f1ez CA,\u00a0S\u00e1ez JC<\/a>,<\/strong> Giaume C, Orellana JA. (2016) \u00a0Cannabinoids prevent the amyloid \u03b2-induced activation of astroglial hemichannels: A neuroprotective mechanism. Glia.\u00a065(1):122-137. doi: 10.1002\/glia.23080.<\/li>\n
Giaume C, S\u00e1ez JC<\/strong><\/a>, Song W, Leybaert L, Naus CC. (2017) Connexins and pannexins in Alzheimer’s disease. Neurosci Lett. 695:100-105 doi: 10.1016\/j.neulet.2017.09.006<\/li>\n
Gonz\u00e1lez A, Herrera G, Ugarte G, Restrepo C, Pi\u00f1a R, Pertusa M, Orio P<\/strong><\/a>, Madrid R. (2017)\u00a0IKD Current in Cold Transduction and Damage-Triggered Cold Hypersensitivity.\u00a0Adv Exp Med Biol.\u00a02017;1015:265-277. doi: 10.1007\/978-3-319-62817-2_14.<\/li>\n
Gonz\u00e1lez A, Ugarte G, Restrepo C, Herrera G, Pi\u00f1a R, G\u00f3mez-S\u00e1nchez JA, Pertusa M, Orio P<\/strong><\/a>, Madrid R. (2017) Role of the excitability brake potassium current IKD in cold allodynia induced by chronic peripheral nerve injury. J Neurosci. 37 (12) 3109-3126; doi: 10.1523\/JNEUROSCI.3553-16.2017.<\/li>\n
Gonz\u00e1lez LF, Henr\u00edquez-Belmar F, Delgado-Acevedo C, Cisternas-Olmedo M, Arriagada G, Sotomayor-Z\u00e1rate R, Murphy DL,\u00a0Moya PR<\/strong><\/a>. (2017) Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice.\u00a0Biol Res. 50(1):29. doi: 10.1186\/s40659-017-0138-3.<\/li>\n
Gonz\u00e1lez-Jamett AM<\/strong><\/a>,\u00a0Baez-Matus X,\u00a0Olivares MJ,\u00a0Hinostroza F, Guerra-Fern\u00e1ndez MJ,\u00a0Vasquez-Navarrete J,\u00a0Thao Bui M,\u00a0Guicheney P,\u00a0Romero NB,\u00a0Bevilacqua JA,\u00a0Bitoun M,\u00a0Caviedes P, C\u00e1rdenas AM<\/a><\/strong>. (2017). \u00a0Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells.\u00a0Scientific Reports.\u00a07(1):4580 doi: 10.1038\/s41598-017-04418-w<\/li>\n
Gonz\u00e1lez-Jamett AM<\/strong><\/a> , Guerra MJ , Olivares MJ , Haro-Acu\u00f1a V , Ba\u00e9z-Matus X , V\u00e1squez-Navarrete J, Momboisse F , Martinez-Quiles N, C\u00e1rdenas AM<\/a><\/strong>.\u00a0(2017).\u00a0The F-Actin Binding Protein Cortactin Regulates the Dynamics of the Exocytotic Fusion Pore through its SH3 Domain.\u00a0Front. Cell. Neurosci.,\u00a0doi: 10.3389 \/fnc el.2017.00130<\/li>\n
Gutierrez-Maldonado SE, Garate JA<\/strong><\/a>, Retamal MJ, Cisternas MA, Volkmann UG, P\u00e9rez-Acle T<\/a><\/strong>\u00a0<\/strong>(2017)\u00a0Accessing the structural and thermodynamic properties of ultra-thin\u00a0layers of C32 adsorbed on a SiO2 surface.\u00a0Chemical Physics Letters.\u00a0674: 64\u201370. doi: 10.1016\/j.cplett.2017.01.065<\/li>\n
Hashimotodani Y, Nasrallah K, Jensen KR, Ch\u00e1vez AE<\/a>,<\/strong> Carrera D, Castillo PE. (2017) LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation\/Inhibition Balance. Neuron. 95(4):928-943.e3. doi: 10.1016\/j.neuron.2017.07.028.<\/li>\n
Latorre R<\/strong><\/a>, Castillo K, Carrasquel-Ursulaez W, Sepulveda RV, Gonzalez-Nilo F<\/a><\/strong>, Gonzalez C<\/strong><\/a>\u00a0and Alvarez O<\/strong>. 2016. Molecular determinants of BK channel functional diversity and functioning. Physiological Reviews, 97(1):39-87 doi:10.1152\/physrev.00001.2016<\/li>\n
Manzanares D, Araya-Dur\u00e1n I, Gallego-Yerga L, J\u00e1tiva P, M\u00e1rquez-Miranda V, Canan J, Jim\u00e9nez Blanco JL, Mellet CO, Gonzalez-Nilo FD<\/a><\/strong>, Garc\u00eda Fern\u00e1ndez JM, Ce\u00f1a V. (2017) Molecular determinants for cyclo-oligosaccharide-based nanoparticle-mediated effective siRNA transfection. Nanomedicine (Lond). 12(13):1607-1621. doi: 10.2217\/nnm-2017-0123.<\/li>\n
M\u00e1rquez-Miranda V, Abrigo J, Rivera JC, Araya-Dur\u00e1n I, Aravena J, Simon F, Pacheco N, Gonzalez-Nilo FD<\/a><\/strong>, Cabello-Verrugio C.\u00a0 (2017) The complex of PAMAM-OH dendrimer with Angiotensin (1-7) prevented the disuse-induced skeletal muscle atrophy in mice. Int J Nanomedicine. 12:1985-1999. doi: 10.2147\/IJN.S125521.<\/li>\n
M\u00e1rquez-Miranda V, Araya-Dur\u00e1n I, Gonzalez-Nilo FD<\/a><\/strong>. (2017).\u00a0Multiescale\u00a0molecular simulations applied to nucleic acid- dendrimer interactions studies. Curr Pharm Des.\u00a023(21):3062-3075. doi: 10.2174\/1381612823666170306093224.<\/li>\n
Martin AJ, Contreras-Riquelme S, Dominguez C, P\u00e9rez-Acle T<\/a><\/strong>. (2017) LoTo: a graphlet based method for the comparison of local topology between gene regulatory networks. PeerJ. 5:e3052. doi: 10.7717\/peerj.3052.<\/li>\n
Maturana CJ, Aguirre A,\u00a0 S\u00e1ez JC<\/strong>.<\/a> (2016) High glucocorticoid levels during gestation activate the inflammasome in hippocampal oligodendrocytes of the offspring. Dev Neurobiol. 77(5):625-642. doi: 10.1002\/dneu.22409<\/li>\n
Mu\u00f1oz PA, M\u00e1rquez SL, Gonzalez-Nilo FD<\/a><\/strong>, M\u00e1rquez-Miranda V, Blamey JM. (2017) Structure and application of antifreeze proteins from Antarctic bacteria.\u00a0Microb Cell Fact. 16(1):138. doi: 10.1186\/s12934-017-0737-2<\/li>\n
Palacios AG<\/a><\/strong>, Escobar M J. and C\u00e9spedes E. (2017) Missing colors: The enactivist approach to\u00a0perception. Constructivist Foundations. 13(1): 117\u2013125. http:\/\/constructivist.info\/13\/1\/117.<\/li>\n
Palacios AG<\/strong><\/a>, Escobar MJ, C\u00e9spedes E (2017). Authors\u2019 Response: Is a Weak Notion of Representation not Compatible with a Contextualist and Enactivist Account of Perception?. Constructivist Foundations, 13 (1): 135-140<\/li>\n
Palominos MF, Verdugo L, Gabaldon C, Pollak B, Ort\u00edz-Sever\u00edn J, Varas MA, Ch\u00e1vez FP,\u00a0Calixto A<\/strong>. (2017) Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in\u00a0Caenorhabditis\u00a0elegans. MBio. 2017 Oct 10;8(5). pii: e01234-17. doi: 10.1128\/mBio.01234-17.<\/li>\n
Pe\u00f1aloza JP, M\u00e1rquez-Miranda V, Caba\u00f1a-Brunod M, Reyes-Ram\u00edrez R, Llancalahuen FM, Vilos C, Maldonado-Biermann F, Vel\u00e1squez LA, Fuentes JA, Gonzalez-Nilo FD<\/a><\/strong>, Rodr\u00edguez-D\u00edaz M, Otero C. (2017) Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines. J Nanobiotechnology. 15(1):1. doi: 10.1186\/s12951-016-0241-6.<\/li>\n
P\u00e9rez-Acle T<\/a>,<\/strong>\u00a0Fuenzalida I, Martin AJM, Santiba\u00f1ez R, Avaria R, Bernardin A, Bustos AM, Garrido D, Jonathan Dushoff, Liu JH. (2017)\u00a0Stochastic simulation of multiscale complex systems with PISKaS: A rule-based approach.\u00a0Biochem Biophys Res Commun. 498(2):342-351. doi: 10.1016\/j.bbrc.2017.11.138<\/li>\n
Pinto BI, Pupo A, Garc\u00eda IE, Mena-Ulecia K, Mart\u00ednez AD<\/strong><\/a>, Latorre R<\/strong><\/a>, Gonzalez C<\/strong><\/a>. (2017)\u00a0Calcium binding and voltage gating in Cx46 hemichannels.\u00a0Sci Rep.\u00a07(1):15851. doi: 10.1038\/s41598-017-15975-5<\/li>\n
Plotkin LI, Davis HM, Cisterna BA,\u00a0S\u00e1ez JC<\/strong><\/a>. (2017)\u00a0Connexins and Pannexins in Bone and Skeletal Muscle.\u00a0Curr Osteoporos Rep. 15(4):326-334. doi: 10.1007\/s11914-017-0374-z. Review<\/li>\n
Puebla C, Retamal MA, Acu\u00f1a R, S\u00e1ez JC<\/strong><\/a>. (2017) Regulation of Connexin-Based Channels by Fatty Acids. Front Physiol. 8:11. doi: 10.3389\/fphys.2017.00011. Review.<\/li>\n
Rubat S, Varas I, Sep\u00falveda R, Almonacid D, Gonzalez-Nilo F<\/a>,<\/strong> Agosin E (2017)\u00a0Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase.\u00a0FEMS Yeast Res. 17(4). doi: 10.1093\/femsyr\/fox032.<\/li>\n
S\u00e1ez JC<\/strong><\/a>. (2017) Unravelling a novel mechanism for the up-regulation of connexin43 gap junctions between cells derived from the blood-brain barrier. J Physiol. 595(8):2411-2412. doi: 10.1113\/JP274027<\/li>\n
S\u00e1ez PJ, Vargas P, Shoji KF, Harcha PA, Lennon-Dum\u00e9nil AM, S\u00e1ez JC<\/strong><\/a> (2017) ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X7 receptors. Sci Signal. 10(506). pii: eaah7107. doi: 10.1126\/scisignal.aah710<\/li>\n
Salazar J, Alarc\u00f3n M, Huerta J, Navarro B, Aguayo D. (2017) Phosphoethanolamine addition to the Heptose I of the Lipopolysaccharide modifies the inner core structure and has an impact on the binding of Polymyxin B to the Escherichia coli outer membrane.\u00a0Arch Biochem Biophys. 620:28-34. doi: 10.1016\/j.abb.2017.03.008<\/li>\n
Sampogna-Mireles D, Araya-Dur\u00e1n ID, M\u00e1rquez-Miranda V, Valencia-Gallegos JA, Gonzalez-Nilo FD<\/a><\/strong>\u00a0(2017) Structural analysis of binding functionality of folic acid-PEG dendrimers against folate receptor.\u00a0J Mol Graph Model. 72:201-208. doi:10.1016\/j.jmgm.2017.01.004.<\/li>\n
Selcho M, Mill\u00e1n C, Palacios-Mu\u00f1oz A, Ruf F, Ubillo L, Chen J, Bergmann G, Ito C, Silva V, Wegener C,\u00a0 Ewer J.<\/strong><\/a> (2017) Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila<\/em>. Nat Commun. 8:15563. doi: 10.1038\/ncomms15563.<\/li>\n
Vargas AA, Cisterna BA, Saavedra-Leiva F, Urrutia C, Cea LA, Vielma AH, Gutierrez-Maldonado SE, Martin AJ, Pareja-Barrueto C, Escalona Y, Schmachtenberg O<\/a><\/strong>, Lagos CF, P\u00e9rez-Acle T<\/a><\/strong>, S\u00e1ez JC<\/strong><\/a>. (2017) On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells. Front Physiol. 8:38. doi: 10.3389\/fphys.2017.00038.<\/li>\n
Vega-Zuniga T, Medina FS, Mar\u00edn G, Letelier JC, Palacios AG<\/strong><\/a>, N\u011bmec P, Schleich CE, Mpodozis J. (2017) Selective binocular vision loss in two subterranean caviomorph rodents: Spalacopus cyanus and Ctenomys talarum. Sci Rep. 7:41704. doi: 10.1038\/srep41704.<\/li>\n
Villanelo F, Escalona Y, Pareja-Barrueto C, Garate JA<\/strong><\/a>, Skerrett IM, P\u00e9rez-Acle T<\/a><\/strong>\u00a0(2017) Accessing gap-junction channel structure-function relationships through molecular modeling and simulations. .BMC Cell Biol. 18(Suppl 1):5. doi: 10.1186\/s12860-016-0121-9. Review.<\/li>\n
Wongsamitkul N, Maldifassi MC, Simeone X, Baur R, Ernst M, Sigel E (2017)\u00a0\u03b1 subunits in GABAA receptors are dispensable for GABA and diazepam action.\u00a0Sci Rep. 7(1):15498. doi: 10.1038\/s41598-017-15628-7.<\/li>\n
Xu K., Maidana JP, Caviedes M, Quero D, Aguirre P and Orio P<\/strong><\/a>. (2017).\u00a0Hyperpolarization-activated current induces period-doubling cascades and chaos in a cold thermoreceptor model.\u00a0Front Comp Neurosci. 11:12. doi: 10.3389\/fncom.2017.00012. eCollection 2017<\/li>\n
Yi C, Ezan P, Fern\u00e1ndez P, Schmitt J, S\u00e1ez JC<\/strong><\/a>, Giaume C, Koulakoff A. (2017) Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer’s disease. Glia. 65(10):1607-1625. doi: 10.1002\/glia.23182<\/li>\n
Zhong G, Akoum N, Appadurai DA, Hayrapetyan V, Ahmed O, Mart\u00ednez AD<\/a>,<\/strong> Beyer EC, Moreno AP. (2017) Mono-Heteromeric Configurations of Gap Junction Channels Formed by Connexin43 and Connexin45 Reduce Unitary Conductance and Determine both Voltage Gating and Metabolic Flux Asymmetry. Front Physiol. 8:346. doi: 10.3389\/fphys.2017.00346.<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2016″ tab_id=”2016″][vc_column_text 0=””]<\/p>\n
\n
Acevedo W, Gonzalez-Nilo F<\/a><\/strong>, Agosin E. (2016) Docking and Molecular Dynamics of Steviol Glycoside-Human Bitter Receptor Interactions. J Agric Food Chem. 64(40):7585-7596<\/li>\n
Aliaga C, Bravo-Moraga F, Gonzalez-Nilo D<\/a><\/strong>, M\u00e1rquez S, L\u00fchr S, Mena G, Rezende MC. (2016)\u00a0Location of TEMPO derivatives in micelles: subtle effect of the probe orientation. Food Chem. 192:395-401<\/li>\n
Asp\u00e9-S\u00e1nchez M, Moreno M, Rivera MI, Rossi A and\u00a0 Ewer J.<\/strong><\/a> (2016) Oxytocin and vasopressin receptor gene polymorphisms: role in social\u00a0and psychiatric traits Frontiers in Neuroscience 28;9:510. doi: 10.3389\/fnins.2015.00510<\/li>\n
Boetsch C, Aguayo-Villegas DR, Gonzalez-Nilo FD<\/a><\/strong>, Lisa \u00c1T, Beassoni PR. (2016) Putative binding mode of Escherichia coli exopolyphosphatase and polyphosphates based on a hybrid in silico\/biochemical approach. Arch Biochem Biophys. 606:64-72. doi: 10.1016\/j.abb.2016.07.005<\/li>\n
Bousquet F, Chauvel I,\u00a0Flaven-Pouchon\u00a0J, Farine JP, Ferveur JF. (2016) Dietary rescue of altered metabolism gene reveals unexpected Drosophila<\/em> mating cues. J Lipid Res. 57(3):443-50. doi: 10.1194\/jlr.M064683.<\/li>\n
Calf\u00fan C, Dom\u00ednguez C, P\u00e9rez-Acle T<\/a><\/strong>, Whitlock KE<\/strong><\/a>. (2016) Changes in Olfactory Receptor Expression Are Correlated With Odor Exposure During Early Development in the zebrafish (Danio rerio). Chem Senses. 1861(5):439-48<\/li>\n
C\u00e1rdenas AM<\/a><\/strong>, Gonz\u00e1lez-Jamett AM<\/strong><\/a>, Cea LA, Bevilacqua JA, Caviedes P. (2016) Dysferlin function in skeletal muscle: Possible pathological mechanisms and therapeutical targets in dysferlinopathies. Exp Neurol. Exp Neurol. 283(Pt A):246-254. doi: 10.1016\/j.expneurol.2016.06.026<\/li>\n
C\u00e1rdenas AM<\/a><\/strong>, Marengo F. (2016) How the stimulus defines the dynamics of vesicle pool recruitment, fusion mode and vesicle recycling in neuroendocrine cells. J Neurochem. 137(6):867-79. doi: 10.1111\/jnc.13565<\/li>\n
Castillo JP, S\u00e1nchez-Rodr\u00edguez JE, Clark Hyde H, Zaelzer CA, Aguayo D, Sep\u00falveda R, Luk LYP, Kent S, Gonzalez-Nilo F<\/a><\/strong>, Bezanilla F<\/strong><\/a>, and Latorre R<\/a><\/strong>. (2016)\u00a0\u03b21 Subunit-Induced Structural Rearrangements of the Ca2+- and Voltage-Activated (BK) Channel. \u00a0Proc. Natl Acad Sci (USA). 113(23):E3231-9<\/li>\n
Cea LA, Balboa E, Puebla C, Vargas AA, Cisterna BA, Escamilla R, Regueira T, S\u00e1ez JC<\/strong><\/a>. (2016) Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels. Biochim Biophys Acta. 1862(10):1891-9. doi: 10.1016\/j.bbadis.2016.07.003<\/li>\n
Cea LA, Bevilacqua JA, Arriagada C, C\u00e1rdenas AM<\/a><\/strong>, Bigot A, Mouly V,\u00a0S\u00e1ez JC<\/a><\/strong>, Caviedes P. (2016)\u00a0The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes. BMC Cell Biol. 17 Suppl 1:15. doi: 10.1186\/s12860-016-0096-6.<\/li>\n
Cea LA, Puebla C, Cisterna BA, Escamilla R, Vargas AA, Frank M, Mart\u00ednez-Montero P, Prior C, Molano J, Esteban-Rodr\u00edguez I, Pascual I, Gallano P, Lorenzo G, Pian H, Barrio LC, Willecke K,\u00a0 S\u00e1ez JC<\/strong><\/a>. (2016) Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis. Cell Mol Life Sci. 73(13):2583-99. doi: 10.1007\/s00018-016-2132-2<\/li>\n
Ch\u00e1vez Andr\u00e9s E<\/strong><\/a>. (2016) \u00bfC\u00f3mo afecta el color al comportamiento?: Una mirada a la vis\u00f3n ultravioleta en mam\u00edferos. Anales Museo de Historia Natural de Valpara\u00edso. Volumen 29, p\u00e1ginas 21-24.<\/li>\n
Chetty S,\u00a0Bhakat S,\u00a0Martin AJ,\u00a0Soliman ME. (2016) Multi-drug resistance profile of PR20 HIV-1 protease is attributed to distorted conformational and drug binding landscape: molecular dynamics insights. J Biomol Struct Dyn. 34(1):135-51.<\/li>\n
Cisterna BA, Vargas AA, Puebla C,\u00a0S\u00e1ez JC<\/strong><\/a>. (2016)\u00a0Connexin hemichannels explain the ionic imbalance and lead to atrophy in denervated skeletal muscles.\u00a0Biochim Biophys Acta. 1862(11):2168-2176. doi: 10.1016\/j.bbadis.2016.08.020<\/li>\n
Diao F, Mena W, Shi J, Park D, Diao F, Taghert P,\u00a0Ewer J<\/strong><\/a>, and White BH. The splice Isoforms of the Drosophila<\/em> Ecdysis Triggering Hormone receptor have developmentally distinct roles. Genetics, 202(1):175-89<\/li>\n
D\u00edaz J, Woudt L, Suazo L, Garrido C, Caviedes P, C\u00e1rdenas AM<\/a><\/strong>, Castiglioni C, Bevilacqua JA. (2016)\u00a0Broadening The Imaging Phenotype of Dysferlinopathy at Different Disease Stages.\u00a0Muscle Nerve. 54(2):203-10. doi: 10.1002\/mus.25045<\/li>\n
Diaz-Franulic I<\/a><\/strong>, Caceres-Molina J, Sep\u00falveda RV, Gonzalez-Nilo F<\/a><\/strong>, and Latorre R<\/a><\/strong>\u00a0 (2016) Structurally driven pharmacology pf transient receptor potential vanilloid1 (TRPV1) channel. Mol Pharm. 90(3):300-8<\/li>\n
Diaz-Franulic I<\/a><\/strong>, Poblete H, Mi\u00f1o G, Gonzalez C<\/strong><\/a>, and\u00a0Latorre R<\/a> <\/strong>(2016)\u00a0Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels Ann. Rev. Biophys. 45:371-98<\/li>\n
English NJ and Garate JA<\/a><\/strong> (2016) Near-microsecond human aquaporin 4 gating dynamics in static and alternating external electric elds: Non-equilibrium molecular dynamics. J Chem Phys. 145(8):085102. doi: 10.1063\/1.4961072<\/li>\n
Escalona Y, Garate JA<\/a><\/strong>, Araya-Secchi R, Huynh T, Zhou R, P\u00e9rez-Acle T<\/a><\/strong>. (2016) Exploring the Membrane Potential of Simple Dual-Membrane Systems as Models for Gap-Junction Channels. Biophys J. 110(12):2678-88. doi: 10.1016\/j.bpj.2016.05.005.<\/li>\n
Ewer J<\/strong><\/a>. (2016) Como elegir un horario para Chile. Anales Museo de Historia Natural de Valpara\u00edso. Volumen 29, p\u00e1ginas 9-13.<\/li>\n
Fern\u00e1ndez A, Pupo A, Mena-Ulecia K and Gonzalez C<\/strong><\/a>\u00a0(2016) Pharmacological modulation of proton channel Hv1 in cancer therapy: Future perspectives\u00a0Mol Pharmacol 90(3):385-402<\/li>\n
Flaven-Pouchon J, Farine JP,\u00a0Ewer J<\/strong><\/a>, Ferveur JF.(2016) Regulation of cuticular hydrocarbon profile maturation by Drosophila<\/em> tanning hormone, bursicon, and its interaction with desaturase activity. Insect Biochem Mol Biol. 79:87-96. doi: 10.1016\/j.ibmb.2016.10.007<\/li>\n
Garate JA<\/a><\/strong>, P\u00e9rez-Acle T<\/a><\/strong>.<\/strong> (2016) From dimers to collective dipoles: Structure and dynamics of methanol\/ethanol partition by narrow carbon nanotubes. J Chem Phys. 144(6):064105<\/li>\n
Garc\u00eda IE, Bosen F, Mujica P, Pupo A, Flores-Mu\u00f1oz C, Jara O, Gonzalez C<\/strong><\/a>, Willecke K and Mart\u00ednez AD<\/strong><\/a>\u00a0(2016)\u00a0From Hyperactive Connexin26\u00a0Hemichannels to Impairments in Epidermal\u00a0Calcium Gradient and Permeability Barrier\u00a0in the Keratitis-Ichthyosis-Deafness\u00a0Syndrome J Invest Dermatol.\u00a0\u00a0136(3):574-83<\/li>\n
Garc\u00eda IE, Prado P, Pupo A, Jara O, Rojas-G\u00f3mez D, Mujica P, Flores-Mu\u00f1oz C, Gonz\u00e1lez-Casanova J, Soto-Riveros C, Pinto BI, Retamal MA,\u00a0Gonzalez C<\/a> <\/strong>and Mart\u00ednez AD<\/strong><\/a>\u00a0(2016)\u00a0Connexinopathies: a structural and functional glimpse.\u00a0BMC Cell Biology. 17 Suppl 1:17. Doi: 10.1186\/s12860-016-0092-x<\/li>\n
Graham Z, Collier L, QinW, Peng Y,\u00a0S\u00e1ez JC<\/strong><\/a>\u00a0, Bauman WA and Christopher Cardozo. (2015) J A soluble activin receptor IIB fails to prevent muscle atrophy in a mouse model of spinal cord injury. J Neurotrauma 33(12):1128-35. doi: 10.1089\/neu.2015.405<\/li>\n
Johnson RG, Le HC, Evenson K, Loberg SW, Myslajek TM, Prabhu A, Manley AM, O’Shea C, Grunenwald H, Haddican M, Fitzgerald PM, Robinson T, Cisterna BA,\u00a0S\u00e1ez JC<\/a>,<\/strong> Liu TF, Laird DW, Sheridan JD. (2016)\u00a0Connexin Hemichannels: Methods for Dye Uptake and Leakage.\u00a0J Membr Biol.249(6):713-741<\/li>\n
Krick S, Wang J, St-Pierre M, Gonzalez C<\/strong><\/a>,<\/strong> Dahl G, Salathe M. (2016)\u00a0Duox2 Regulates Pannexin1-mediated ATP Release in Primary Human Airway Epithelial Cells via changes in intracellular pH and not H2O2 production.\u00a0J Biol Chem. 291(12):6423-32. doi: 10.1074\/jbc.M115.664854.<\/li>\n
Lions S and Pe\u00f1a M Reading Comprehension in Latin America: Difficulties and Possible Interventions New Dir Child Adolesc Dev. 2016(152):71-84. doi: 10.1002\/cad.20158.<\/li>\n
M\u00e1rquez-Miranda V, Araya-Dur\u00e1n I, Camarada MB, Comer J, Valencia-Gallegos JA, Gonzalez-Nilo FD<\/a><\/strong>.<\/strong> (2016)\u00a0Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction.\u00a0Sci Rep. 2016 Jul 5;6:29436. doi: 10.1038\/srep29436.<\/li>\n
M\u00e1rquez-Miranda V, Pe\u00f1aloza JP, Araya-Dur\u00e1n I, Reyes R, Vidaurre S, Romero V, Fuentes J, C\u00e9ric F, Vel\u00e1squez L, Gonzalez-Nilo F<\/a><\/strong>, Otero C. (2016) Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake. Nanoscale Res Lett. 2016 Dec;11(1):66.<\/li>\n
Marracino P, Liberti M, Trapani E, Burnham CJ, Avena M,\u00a0 Garate JA<\/strong><\/a>, Apollonio F, English NJ. (2016) Human Aquaporin 4 Gating Dynamics under Perpendicularly-Oriented Electric-Field Impulses: A Molecular Dynamics Study. Int J Mol Sci. 17(7). pii: E1133. doi: 10.3390\/ijms17071133.<\/li>\n
Martin AJ, Dominguez C, Contreras-Riquelme S, Holmes DS, P\u00e9rez-Acle T<\/a><\/strong>.<\/strong> (2016) Graphlet Based Metrics for the Comparison of Gene Regulatory Networks. PLoS One. 2016 Oct 3;11(10):e0163497. doi: 10.1371\/journal.pone.0163497.<\/li>\n
Mart\u00ednez AD<\/strong><\/a>, Jara O, Ceriani R, Maripill\u00e1n J, Mujica P, Garc\u00eda IE (2016)\u00a0Methods to determinate formation of heteromeric hemichannels.\u00a0Book title: Gap Junction and Pannexin Channels \u201cA Volume in the\u00a0Methods in Signal Transduction Series\u201d. Chapter 11.<\/li>\n
Mart\u00ednez G, Vidal RL, Mardones P, Serrano FG, Ardiles AO, Wirth C, Vald\u00e9s P, Thielen P, Schneider BK, Kerr B, Vald\u00e9s JL, Palacios AG<\/strong><\/a>, Inestrosa NC, Glimcher LH, Hetz C. Regulation of memory formation by the transcription factor XBP1. (2015). Cell-Report.14(6):1382-9<\/li>\n
Mena W, Diegelmann S, Wegener C,\u00a0Ewer J<\/strong><\/a>. (2016) Stereotyped responses of\u00a0Drosophila\u00a0<\/em>peptidergic neuronal ensemble depend on downstream neuromodulators. Elife. 2016 Dec 15;5. pii: e19686. doi: 10.7554\/eLife.19686.<\/li>\n
Moldenhauer H, Diaz-Franulic I<\/a><\/strong>, Gonzalez-Nilo F<\/a><\/strong>,Naranjo D\u00a0(2016). Effective pore size and radius of capture for K+ ions in K-channels. Scientific Reports. 6:1989<\/li>\n
Moya-D\u00edaz J, \u00c1lvarez JD, Montenegro M, Bayon\u00e9s L, Belingheri AV, Gonz\u00e1lez-Jamett AM<\/strong><\/a>, C\u00e1rdenas AM<\/a><\/strong>, Marengo FD (2016) Sustained exocytosis after action potential-like stimulation at low frequencies in mouse chromaffin cells depends on a dynamin-dependent fast endocytotic process. Front Cell Neurosci. 10:184. doi: 10.3389\/fncel.2016.00184<\/li>\n
Moya Vera PR<\/strong><\/a>. (2016)\u00a0Interacciones gen\u00e9tico-ambientales en el comportamiento.\u00a0Anales Museo de Historia Natural de Valpara\u00edso. Volumen 29, p\u00e1ginas 28-32.<\/li>\n
Mu\u00f1oz P, Estay C, D\u00edaz P, Elgueta C, Ardiles \u00c1O, Lizana PA (2016)Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats. Neural Plast. 2016:4783836. doi: 10.1155\/2016\/4783836.<\/li>\n
Naranjo D, Moldenhauer H, Pincuntureo M. and Diaz-Franulic I<\/a><\/strong> (2016) Pore size matters for potassium channel conductance. J Gen Physiol 148(4):277-91. doi: 10.1085\/jgp.201611625.<\/li>\n
Olivares, J. (2016) Rese\u00f1a bibliogr\u00e1fica sobre la ara\u00f1a de rinc\u00f3n (Loxosceles Laeta, Fam. Sicariirae): Que sabemos y que necesitamos saber.\u00a0Anales Museo de Historia Natural de Valpara\u00edso. Volumen 29, p\u00e1ginas 53-56.<\/li>\n
Park J, Ch\u00e1vez AE<\/strong><\/a>, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S. (2016) CaMKII Phosphorylation of TARP\u03b3-8 Is a Mediator of LTP and Learning and Memory. Neuron. 92(1):75-83. doi: 10.1016\/j.neuron.2016.09.002<\/li>\n
P\u00e9rez-N\u00fa\u00f1ez R, Barraza N, Gonzalez-Jamett A<\/strong><\/a>, C\u00e1rdenas AM<\/a><\/strong>, Barnier JV, Caviedes P. (2016)\u00a0Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated\u00a0Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and Extension.\u00a0Neurotox Res. 30(1):76-87. doi: 10.1007\/s12640-016-9613-<\/li>\n
Pinto BI, Garc\u00eda IE, Pupo A, Retamal MA, Mart\u00ednez AD<\/a><\/strong>, Latorre R<\/a><\/strong>\u00a0and Gonzalez C<\/a><\/strong>\u00a0(2016)\u00a0Charged residues at the first transmembrane region contribute to the voltage dependence of connexins slow gate. J Biol Chem 291(30):15740-52. doi: 10.1074\/jbc.M115.709402<\/li>\n
Puebla C, Cisterna BA, Salas DP, Delgado-L\u00f3pez F, Lampe PD,\u00a0S\u00e1ez JC<\/a>.<\/strong> (2016) Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism. Biochim Biophys Acta. 1861(5):439-48<\/li>\n
Qiu F, Chamberlin A, Watkins BM, Ionescu A, Perez ME, Barro-Soria R, Gonzalez C<\/strong><\/a>, Noskov SY and Larsson HP (2016) Molecular mechanism of Zn2+ inhibition of a\u00a0voltage-gated proton channel.\u00a0Proc Natl Acad Sci U S A 113(40):E5962-E5971<\/li>\n
Retamal MA, Garc\u00eda IE, Pinto B, Pupo A, Baez-Nieto D, Stehberg J, Del Rio R, Gonzalez C<\/strong><\/a>. (2016) Extracellular cysteine in connexins: role as redox sensors. Front in Physiol 7:1<\/li>\n
S\u00e1ez JC<\/strong><\/a>. (2016) Proceedings of the International Gap Junction Conference 2015. BMC Cell Biol. 17 Suppl 1:18. doi: 10.1186\/s12860-016-0097-5<\/li>\n
Salazar C, Valdivia G, Ardiles AO,\u00a0Ewer J<\/a><\/strong>, Palacios AG<\/strong><\/a>. (2016). Genetic variants associated with neurodegenerative Alzheimer disease in natural model. Biological Research. Special Issue. 26;49(1):14<\/li>\n
Salvador-Morales C, Brahmbhatt B, M\u00e1rquez-Miranda V, Araya-Duran I, Canan J, Gonzalez-Nilo F<\/a><\/strong>, Vilos C, Cebral J, Mut F, Lohner R, Leong B, Sundaresan G, Zweit J. (2016)\u00a0Mechanistic Studies on the Self-Assembly of PLGA Patchy Particles and Their Potential Applications in Biomedical Imaging.\u00a0Langmuir. 32(31):7929-42. doi: 10.1021\/acs.langmuir.6b02177<\/li>\n
Savalli N, Pantazis A,Sigg D, Weiss JN, Neely A<\/strong><\/a> and Olcese R (2016) The \u03b12\u03b4-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials J Gen Physiol. 148(2):147-59. doi: 10.1085\/jgp.201611586<\/li>\n
Sep\u00falveda-Crespo D, Vacas-C\u00f3rdoba E, M\u00e1rquez-Miranda V, Araya-Dur\u00e1n I, G\u00f3mez R, Mata FJ, Gonzalez-Nilo FD<\/a><\/strong>, Mu\u00f1oz-Fern\u00e1ndez M\u00c1. (2016) Effect of Several HIV Antigens Simultaneously Loaded with G2-NN16 Carbosilane Dendrimer in the Cell Uptake and Functionality of Human Dendritic Cells. Dec 21;27(12):2844-2849. doi: 10.1021\/acs.bioconjchem.6b00623.<\/li>\n
Vald\u00e9s J, Trachsel-Moncho L, Sahaboglu A, Trifunovic D, Miranda M, Ueffing M, Paquet-Durand F, Schmachtenberg O<\/strong><\/a>\u00a0(2016). Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies. ALTEX,33(4):459-464<\/li>\n
Vielma, A.H. and Schmachtenberg O<\/strong><\/a>. Electrophysiological fingerprints of OFF bipolar cells in rat retina. Sci. Rep.,6:30259 doi: 10.1038\/srep30259<\/li>\n
Wang H, Ardiles A, Yang S, Valdivia G, Baek M, Tran T, Posada-Duque R, Chuang YA, Palacios AG<\/strong><\/a>,<\/strong> Gallagher M, Worley P, Kirkwood A. (2016). Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the hippocampus. Journal of Neuroscience 36(5):1723-9<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2015″ tab_id=”2015″][vc_column_text 0=””]<\/p>\n
\n
Aguayo D, Pacheco N, Morales EH, Collao B, Luraschi R, Cabezas C, Calder\u00f3n P, Gonzalez-Nilo F<\/a><\/strong>, Gil F, Calder\u00f3n IL, Saavedra CP (2015)\u00a0Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel. \u00a0Arch Biochem Biophys. 568:38-45 Doi: 10.1016\/j.abb.2015.01.005<\/li>\n
Arias-Darraz L,\u00a0Cabezas D,\u00a0Colenso CK,\u00a0Alegr\u00eda-Arcos M,\u00a0Bravo-Moraga F,\u00a0Varas-Concha I,\u00a0Almonacid DE,\u00a0Madrid R,\u00a0Brauchi S. (2015) A transient receptor potential ion channel in Chlamydomonas shares key features with sensory transduction-associated TRP channels in mammals. Plant Cell. 27(1):177-88. Doi: 10.1105\/tpc.114.131862.<\/li>\n
Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, P\u00e9rez-Acle T<\/a>,<\/strong> Skerrett IM (2015)\u00a0Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32.\u00a0J Biol Chem. 290(28):17074-84 Doi: 10.1074\/jbc.M115.650747<\/li>\n
Camarada MB, M\u00e1rquez-Miranda V, Araya-Dur\u00e1n I, Y\u00e9venes A, Gonzalez-Nilo F<\/a><\/strong>. (2015) PAMAM G4 dendrimers as inhibitors of the iron storage properties of human L-chain ferritin. Phys Chem Chem Phys. 17(29):19001-11. Doi: 10.1039\/c5cp02594j<\/li>\n
Carrasquel-Ursulaez W, Contreras GF, Sep\u00falveda R, Aguayo D, Gonzalez-Nilo F<\/a><\/strong>, Gonzalez C<\/strong><\/a>\u00a0and Latorre R<\/strong><\/a>. (2015) Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel. \u00a0J Gen Physiol. 145(1):61-74. Doi: 10.1085\/jgp.201411194<\/li>\n
Carrasquel-Ursulaez W, Moldenhauer H, Castillo JP, Latorre R<\/strong><\/a>\u00a0& Alvarez O. (2015) Biophysical analysis of thermosensitive TRP channels with a special focus on the cold receptor TRPM8. \u00a0Temperature. 145(1):61-74. oi: 10.1080\/23328940.2015.1047558<\/li>\n
Castillo, JP, Rui, H, Basilio, D, Das, A, Roux, B, Latorre R<\/strong><\/a>, Bezanilla, F<\/a><\/strong>, Holmgren, M. (2015). Mechanism of potassium ion uptake by the Na(+)\/K(+)-ATPase. Nature Comm. 6:7622. oi: 10.1038\/ncomms8622<\/li>\n
Castillo K, Contreras GF, Pupo A, Torres Y,\u00a0Neely A<\/a>,<\/strong> Gonzalez C<\/strong><\/a>\u00a0and Latorre R<\/strong><\/a>. (2015) Molecular mechanism underlying \u03b21 regulation in voltage- and calcium-activated potassium (BK) channels.\u00a0Proc Natl Acad Sci U S A. 112(15):4809-14. Doi: 10.1073\/pnas.1504378112<\/li>\n
Castillo K, Pupo A, Baez-Nieto D, Contreras G;\u00a0Morera FJ,\u00a0Neely A<\/strong><\/a>, Latorre R<\/strong><\/a>, Gonzalez C<\/a><\/strong>. (2015)\u00a0Voltage-Gated Proton (Hv1) Channels, a Singular Voltage Sensing Domain. FEBS Letters . 589(22):3471-8 Doi: 10.1016\/j.febslet.2015.08.003.<\/li>\n
Cerquera A, Mu\u00f1oz J, Araya J, G\u00f3mez O (2015)\u00a0Registro de actividad el\u00e9ctrica en la retina de una rata albina empleando una matriz de microelectrodos. Acta biol\u00f3gica colombiana\u00a020(3):37-46. Doi: 10.15446\/abc.v20n3.46216<\/li>\n
Cort\u00e9s-Campos C, Letelier J, Ceriani R, Whitlock KE<\/strong><\/a>. (2015).\u00a0Zebrafish adult-derived hypothalamic neurospheres generate gonadotropin-releasing hormone (GnRH) neurons.\u00a0Biol Open 4(9):1077-86. oi: 10.1242\/bio.010447<\/li>\n
Diao F, Ironfield H, Diao F, Luan H, Shropshire W,\u00a0Ewer J<\/strong><\/a>, \u00a0Marr E, Potter CJ, Landgraf M and White BH (2015) Plug-and-Play Genetic Access to Drosophila<\/em> Cell Types Using Exchangeable Exon Cassettes. Cell Reports.\u00a010(8):1410-21. Doi: 10.1016\/j.celrep.2015.01.059<\/li>\n
Diaz-Franulic I<\/a><\/strong>., Sep\u00falveda R, Navarro-Quezada N, F. Gonzalez-Nilo FD<\/a><\/strong>\u00a0and\u00a0Naranjo D. (2015). \u00a0Pore dimensions and the role of occupancy in unitary conductance of Shaker K-channels. The Journal of General Physiology.146:133-146. Doi: 10.1085\/jgp.201411353.<\/li>\n
Du LY, Chang LY, Ardiles AO, Tapia-Rojas C, Araya J, Inestrosa NC, Palacios AG<\/strong><\/a>, Acosta ML. (2015) Alzheimer\u2019s disease-related protein expression in the retina of Octodon degus. PLoS One. 2015 Aug 12;10(8):e0135499. oi: 10.1371\/journal.pone.0135499<\/li>\n
Duran-Lara EF, Avila-Salas F, Galaz S, John A, Marican A, Gutierrez M, Nachtigall FM, Gonzalez-Nilo FD<\/a><\/strong>, Santos LS. (2015) Nano-Detoxification Of Organophosphate Agents By PAMAM Derivatives. J Braz Chem Soc 26(3): 580-91. Doi: 10.5935\/0103-5053.20150013<\/li>\n
Dur\u00e1n-Lara EF, L\u00f3pez-Cort\u00e9s XA, Castro RI, Avila-Salas F, Gonzalez-Nilo FD<\/a><\/strong>, Laurie VF, Santos LS. (2015)\u00a0Experimental and theoretical binding affinity between polyvinylpolypyrrolidone and selected phenolic compounds from food matrices. \u00a0Food Chem.\u00a0168:464-70. oi: 10.1016\/j.foodchem.2014.07.048<\/li>\n
Elgueta C, Vielma AH, Palacios AG<\/a><\/strong>\u00a0and Schmachtenberg O<\/strong><\/a>. (2015) Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells.\u00a0Front.\u00a0Cell. Neurosci. 9:6 Doi: 10.3389\/fncel.2015.00006<\/li>\n
Ferreira G, Raddatz N, Lorenzo Y, Gonzalez C<\/strong><\/a>\u00a0and Latorre R<\/strong><\/a>\u00a0(2015)\u00a0Biophysical and Molecular Features\u00a0of Thermosensitive TRP Channels Involved\u00a0in Sensory Transduction\u00a0. Cahpter in:\u00a0TRP Channels in Sensory Transduction,\u00a0R. Madrid, J. Bacigalupo (eds.).\u00a0Springer International Publishing Switzerland<\/li>\n
Garc\u00eda IE, Maripill\u00e1n J, Jara O, Ceriani R, Palacios-Mu\u00f1oz A, Ramachandran J, Olivero P, P\u00e9rez-Acle T<\/a><\/strong>,<\/strong> Gonzalez C<\/strong><\/a>,<\/strong>\u00a0S\u00e1ez JC<\/strong><\/a>, Contreras JE, Mart\u00ednez AD<\/a><\/strong>.\u00a0(2015)Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43.\u00a0J Invest Dermatol. 135(5):1338-47. oi: 10.1038\/jid.2015.20<\/li>\n
Garcia-Elias A, Berna-Erro A, Rubio-Moscardo F, Pardo-Pastor C, Mrkonji\u0107 S, Sep\u00falveda RV, Vicente R, Gonzalez-Nilo FD<\/a><\/strong>, Valverde MA. (2015) Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels. Structure. 23(8):1404-13. Doi: 10.1016\/j.str.2015.05.018<\/li>\n
Garc\u00eda-Puente Y, Prado-Guti\u00e9rrez P, Mart\u00ednez-Montes E (2015) Time-frequency methods for studying non-stationary auditory responses. IFMBE Proceedings.\u00a0\u00a049: 540-543. https:\/\/doi.org\/10.1007\/978-3-319-13117-7_138<\/li>\n
Garc\u00eda-Puente Y, Prado-Guti\u00e9rrez P, Mart\u00ednez-Montes (2015) Evaluaci\u00f3n de m\u00e9todos para la estimaci\u00f3n de la respuestaauditiva de seguimiento de la modulaci\u00f3n. CENIC Ciencias Biologicas.<\/li>\n
Harcha PA, Vargas A, Yi C, Koulakoff AA, Giaume C,\u00a0 S\u00e1ez JC<\/strong><\/a>\u00a0. (2015)\u00a0Hemichannels Are Required for Amyloid \u03b2-Peptide-Induced Degranulation and Are Activated in Brain Mast Cells of APPswe\/PS1dE9 Mice.\u00a0J Neurosci. 35(25):9526-38. Doi: 10.1523\/JNEUROSCI.3686-14.2015<\/li>\n
Inestrosa NC, Rios JA, Cisternas P, Tapia-Rojas C, Rivera D, Braidy N, Zolezzi JM, Godoy JA, Carvajal FJ, Ardiles AO, Bozinovic F, Palacios AG<\/strong><\/a>, Sachdev PS. (2015). Age progression of neuropathological markers in the brain of the Chilean rodent\u00a0Octodon degus,\u00a0a natural model of Alzheimer\u2019s disease. Brain Pathology. 25(6):679-91. Doi: 10.1111\/bpa.1222<\/li>\n
Kalinowska M, Ch\u00e1vez AE<\/a><\/strong>, Lutzu S, Castillo PE, Bukauskas FF, Francesconi A. Actinin-4 (2015) Governs Dendritic Spine Dynamics and Promotes Their Remodeling by Metabotropic Glutamate Receptors. J Biol Chem. 290(26):15909-20. Doi: 10.1074\/jbc.M115.640136<\/li>\n
Kr\u00fcger E. Mena W, Lahr EC, Johnson EC and\u00a0 Ewer J<\/strong><\/a>. (2015). Genetic analysis of Eclosion Hormone action during Drosophila<\/em> larval ecdysis. Development, 142(24):4279-4287. Doi: 10.1242\/dev.126995<\/li>\n
Langenhan T, Barr MM, Bruchas MR, Ewer J<\/a>,<\/strong> Griffith LC, Maiellaro I, Taghert PH, White BH, Monk KR (2015) Model Organisms in GPCR Research. Mol Pharmacol. 88(3):596-603. Doi: 10.1124\/mol.115.098764<\/li>\n
Leiva V, Tejo M, Guiraud P, Schmachtenberg O<\/strong><\/a>, Orio P<\/strong><\/a>\u00a0and Marmolejo-Ramos F. \u00a0Modeling neural activity with cumulative damage distributions. Biological Cybernetics. 109(4-5):421-33. Doi: 10.1007\/s00422-015-0651-9<\/li>\n
L\u00f3pez-Caba\u00f1a ZE, Vald\u00e9s O, Vergara CE, Camarada MB, Nachtigall FM, Gonzalez-Nilo FD<\/a><\/strong>, Santos LS (2015)\u00a0Photophysical Studies Of The Interactions Of Poly(amidoamine) Generation Zero (PAMAM G0) With Copper And Zinc Ions. Journal Of Luminescence 164:23-30. Doi: 10.1016\/j.jlumin.2015.03.019<\/li>\n
M\u00e1rquez-Miranda V, Camarada MB, Araya-Dur\u00e1n I, Varas-Concha I, Almonacid DE, Gonzalez-Nilo F<\/a><\/strong>.<\/strong> (2015) Biomimetics: From Bioinformatics to Rational Design of Dendrimers as Gene Carriers. PLoS One. 10(9):e0138392. Doi: 10.1371\/journal.pone.013839<\/li>\n
Min\u0303o-Galaz\u00a0GA. \u00a0(2015) \u00a0Allosteric Communication Pathways and Thermal Rectification in PDZ\u20112 Protein: A Computational Study \u00a0J. Phys Chem B . 119(20):6179-89. Doi: 10.1021\/acs.jpcb.5b02228<\/li>\n
Mi\u00f1o-Galaz GA, Gutierrez G (2015) Hydrogen bonds and asymmetrical heat diffusion in \u0002alpha helices. A computational analysis Chemical Physics Letters 635:16-2. Doi: 10.1021\/acs.jpcb.5b02228<\/li>\n
Morales-Camilo N, Salas CO, Sanhueza C, Espinosa-Bustos C, Sep\u00falveda-Boza S, Reyes-Parada M, Gonzalez-Nilo F<\/a><\/strong>, Caroli Rezende M, Fierro A. (2014)\u00a0Synthesis, biological evaluation and molecular simulation of chalcones and aurones as selective MAO-B inhibitors.\u00a0Chem Biol Drug Des. 85(6):685-95 Doi: 10.1111\/cbdd.12458<\/li>\n
Morera FJ, Baez-Nieto D, Lorenzo Y, Castillo K, Pupo A, Vargas-Chacoff L and Gonzalez C<\/a><\/strong>\u00a0(2015) Role of ion channels in salt secretion by atlantic salmon gills during acclimation to seawater. \u00a0Physiological Mini Reviews, 8(1)<\/li>\n
Morera FJ, Saravia J, Pontigo JP, Vargas-Chacoff L, Contreras GF, Pupo A, Lorenzo Y, Castillo K, Tilegenova C, Cuello LG, Gonzalez C<\/strong><\/a>.<\/strong> (2015) Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: new therapeutics opportunities as targets in human diseases. Pharmacol Res. 101:56-64 Doi: 10.1016\/j.phrs.2015.08.011<\/li>\n
Naranjo D, Wen H and Brehm P (2015). Zebrafish CaV2.1 Calcium Channels Are Tailored for Fast Synchronous Neuromuscular Transmission. Biophysical Journal 108(3):578-84. Doi: 10.1016\/j.bpj.2014.11.3484<\/li>\n
Olivares E, Orio P<\/strong><\/a>. (2015) Mathematical Modeling of TRPM8 and the Cold Thermoreceptors. In: TRP Channels in Sensory Transduction. Madrid, R.; Bacigalupo, J.,editors. Springer International Publishing<\/li>\n
Olivares E, Salgado S, Maidana JP, Herrera G, Campos M, Madrid R and Orio P<\/strong><\/a>\u00a0(2015). TRPM8-dependent dynamic response in a mathematical model of cold thermoreceptor. PLOS One 588(Pt 17):3141-8 Doi: 10.1371\/journal.pone.0139314<\/li>\n
Orellana JA, Moraga-Amaro R, D\u00edaz-Galarce R, Rojas S, Maturana CJ, Stehberg J,\u00a0S\u00e1ez JC<\/a>\u00a0.<\/strong> (2015)\u00a0Restraint stress increases hemichannel activity in hippocampal glial cells and neurons.\u00a0Front Cell Neurosci. 9:102. Doi: 10.3389\/fncel.2015.00102.<\/li>\n
Poblete H, Oyarz\u00fan I, Olivero P, Comer J, Zu\u00f1iga M, Sepulveda RV, B\u00e1ez-Nieto D,\u00a0 Gonzalez Leon C<\/strong><\/a>, Gonzalez-Nilo F<\/a><\/strong>, Latorre R<\/strong><\/a>. (2015) Molecular Determinants of Phosphatidylinositol 4,5Bisphosphate (PI(4,5)P2) Binding to Transient Receptor Potential V1 (TRPV1) Channels. J Biol Chem. 290(4):2086-98. Doi: 10.1074\/jbc.M114.613620<\/li>\n
Prado-Gutierrez P, Castro-Fari\u00f1as A, Morgado-Rodriguez L, Velarde-Reyes E, Mart\u00ednez AD<\/strong><\/a>, Mart\u00ednez-Montes E.\u00a0 (2015) Habituation of auditory steady state responses evoked by amplitude-modulated acoustic signals in rats. Audiology Research 5(113):21-28. Doi: 10.4081\/audiores.2015.113<\/li>\n
Retamal MA,\u00a0Le\u0002on-Paravic CG,\u00a0Ezquer M,\u00a0Ezquer F,\u00a0Del Rio R,\u00a0Pupo A, Mart\u00ednez AD<\/strong><\/a>, Gonzalez C<\/strong><\/a>\u00a0(2015) Carbon Monoxide: A New Player in the Redox\u00a0Regulation of Connexin Hemichannels.\u00a0IUBMB Life 67(6):428-37. Doi: 10.1002\/iub.1388<\/li>\n
Retamal MA, Reyes EP, Garc\u00eda IE, Pinto B, Mart\u00ednez AD<\/strong><\/a>\u00a0Gonzalez C<\/a><\/strong>\u00a0(2015) Diseases associated with leaky hemichannels. Frontiers in Cellular Neuroscience. 9:267. Doi: 10.3389\/fncel.2015.00267<\/li>\n
Riquelme MA, Cea LA, Vega JL, Puebla C, Vargas AA, Shoji KF, Subiabre M,\u00a0 S\u00e1ez JC<\/strong><\/a>. (2015) Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation. Front Cell Dev Biol. 3:25.\u00a0Doi: 10.3389\/fcell.2015.00025<\/li>\n
Rivas-Aravena A, Fuentes Y, Cartagena J, Brito T, Poggio V, La Torre J, Mendoza H, Gonzalez-Nilo F<\/a><\/strong>, Sandino AM, Spencer E. (2015) Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant. Fish Shellfish Immunol. 45(1): 157-166. Doi: 10.1016\/j.fsi.2015.03.033<\/li>\n
Rovegno M, Soto PA, S\u00e1ez PJ, Naus CC,\u00a0S\u00e1ez JC<\/a><\/strong>\u00a0and von Bernhardi R. (2015) \u00a0Connexin43 hemichannels mediate secondary cellular damage spread from the trauma zone to distal zones in astrocyte monolayers. Glia 63(7):1185-99. Doi: 10.1002\/glia.22808<\/li>\n
S\u00e1ez JC<\/strong><\/a>, Cisterna BA, Vargas A, Cardozo CP. (2015) Regulation of pannexin and connexin channels and their functional role in skeletal muscles. Cell Mol Life Sci. 72(15):2929-35. Doi: 10.1007\/s00018-015-1968-1<\/li>\n
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Suzuki K, Lovera M, Schmachtenberg O<\/a><\/strong>\u00a0and Couve E. (2015) Axonal Degeneration in Dental Pulp precedes Primary Teeth Exfoliation. J Dental Res. 94(10):1446-53. Doi: 10.1177\/0022034515593055<\/li>\n
Talaver\u00f3n R, Fern\u00e1ndez P, Escamilla R, Pastor AM, Matarredona ER,\u00a0 S\u00e1ez JC<\/strong><\/a>\u00a0(2015)\u00a0\u00a0Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells. Front Cell Neurosci. 9:411. Doi: 10.3389\/fncel.2015.00411<\/li>\n
Tindi JO,\u00a0Ch\u00e1vez AE<\/strong><\/a>, Cvejic S, Calvo-Ochoa E, Castillo PE, Jordan BA. (2015) ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization.\u00a0J Neurosci. 35(24):8986-96. Doi: 10.1523\/JNEUROSCI.4029-14.2015.<\/li>\n
Vald\u00e9s, J, Olivares J, Ponce D, and Schmachtenberg O<\/strong><\/a>\u00a0(2015) Analysis of olfactory sensitivity in rainbow trout (Oncorhynchus mykiss) reveals their ability to detect lactic acid, pyruvic acid and four B-vitamins. Fish Physiol. Biochem., 41(4):879-85. Doi: 10.1007\/s10695-015-0054-9<\/li>\n
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[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2014″ tab_id=”2014″][vc_column_text 0=””]<\/p>\n
\n
Abarca F, Gutierrez-Maldonado SE, Parada P, Martinez P, Maass A and P\u00e9rez-Acle T<\/a><\/strong>\u00a0<\/strong>(2014) Insights on the structure and stability of Licanantase: a trimeric acid-stable\u00a0coiled-coil lipoprotein from\u00a0Acidithiobacillus thiooxidans. Peer J. 2:e457.\u00a0Doi: 10.7717\/peerj.457.<\/li>\n
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Arenas-Salinas M, Townsend PD, Brito C, Marquez V, Marabolli V, Gonzalez-Nilo F<\/a><\/strong>, Matias C, Watt RK, L\u00f3pez-Castro JD, Dom\u00ednguez-Vera J, Pohl E, Y\u00e9venes A. (2014)\u00a0The crystal structure of ferritin from Chlorobium tepidum reveals a new conformation of the 4-fold channel for this protein family. Biochimie. 106:39-47 Doi: 10.1016\/j.biochi.2014.07.019.<\/li>\n
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Brito C, Matias C, Gonzalez-Nilo FD<\/a><\/strong>, Watt RK, Y\u00e9venes A. (2014)\u00a0The C-Terminal Regions Have an Important Role in the Activity of the Ferroxidase Center and the Stability of Chlorobium tepidum Ferritin.\u00a0Protein J. 33(3):211-20 Doi: 10.1007\/s10930-014-9552-3.<\/li>\n
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Cea LA, Riquelme MA, Vargas AA, Urrutia C,\u00a0S\u00e1ez JC,<\/strong><\/a>. (2014)\u00a0Pannexin 1 channels in skeletal muscles. \u00a0Front Physiol. 5:139. Doi: 10.3389\/fphys.2014.00139.<\/li>\n
Chang LYL, Lowe J, Ardiles A, Lim J, Grey AC, Robertson K, Danesh-Meyer H, Palacios AG<\/strong><\/a>, Acosta ML (2014). Alzheimer\u2019s disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers. Alzheimer\u2019s & Dementia. 10(2):251-261. Doi: 10.1016\/j.jalz.2013.06.004.<\/li>\n
Cisterna BA, Cardozo C and\u00a0S\u00e1ez JC<\/strong><\/a>\u00a0(2014)\u00a0Neuronal involvement in muscular atrophy.\u00a0Front. Cell. Neurosci. 8:405. Doi: 10.3389\/fncel.2014.00405<\/li>\n
Cornejo I, Andrini O, Niemeyer MI, Marabol\u00ed V, Gonzalez-Nilo FD<\/a><\/strong>, Teulon J, Sep\u00falveda FV, Cid LP. (2014)\u00a0Identification and Functional Expression of a Glutamate- and Avermectin-Gated Chloride Channel from Caligus rogercresseyi, a Southern Hemisphere Sea Louse Affecting Farmed Fish.\u00a0PLoS Pathog.\u00a010(9):e1004402. Doi: 10.1371\/journal.ppat.1004402.<\/li>\n
Couve E, Osorio R, Schmachtenberg O<\/strong><\/a>\u00a0(2014)\u00a0Reactionary Dentinogenesis and Neuroimmune Response in Dental Caries. J Dent Res. 93(8):788-793. Doi: 10.1177\/0022034514539507.
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Figueroa VA, Retamal MA, Cea LA, Salas JD, Vargas AA, Verdugo CA, Jara O, Mart\u00ednez AD<\/strong><\/a>\u00a0and\u00a0S\u00e1ez JC<\/strong><\/a>\u00a0\u00a0(2014)\u00a0Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca2+ signaling in HeLa cells.\u00a0Front. Cell. Neurosci. 8:265. Doi: 10.3389\/fncel.2014.00265.<\/li>\n
Garate JA<\/strong><\/a>, P\u00e9rez-Acle T<\/a><\/strong>\u00a0and Oostenbrink C (2014)\u00a0On the thermodynamics of carbon nanotube single-file water loading: Free energy, Energy and Entropy calculations Phys. Chem. Chem. Phys.\u00a016(11):5119-28. Doi: 10.1039\/c3cp54554g.<\/li>\n
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Gonzalo Hern\u00e1ndez, Carlos Jaime Barrios Hern\u00e1ndez, Gilberto D\u00edaz, Carlos Garcia Garino, Sergio Nesmachnow, P\u00e9rez-Acle T<\/a><\/strong>, Mario Storti, Mariano Vasquez (Editors). High Performance Computing. Communications in Computer and Information Science. First HPCLATAM \u2013 CLCAR Latin American Conference CARLA 2014. Springer-Verlag Berlin Heidelberg 2014. ISBN 978-3-662-45482-4<\/li>\n
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Leiva A, Fuentes I, Bossel E, Urzua M, Mendez M, Pino M, Radic D, M\u00e1rquez V, Gonzalez-Nilo FD<\/a><\/strong>\u00a0(2014) Block Copolymers In The Synthesis Of Gold Nanoparticles. Two New Approaches: Copolymer Aggregates As Reductants And Stabilizers And Simultaneous Formation Of Copolymer Aggregates And Gold Nanoparticles. J Of Polymer Science, 2014. 52(21):3069\u201379. Doi:10.1002\/pola.27354<\/li>\n
Mart\u00edn P, Moncada M, Enrique N, Asuaje A, Valdez Capuccino JM, Gonzalez C<\/strong><\/a>, Milesi V. \u00a0(2014) Arachidonic acid activation of BKCa (Slo1) channels associated with the \u03b2 1 subunit in human vascular smooth muscle cells. Pfl\u00fcgers Archiv European Journal of Physiology 466(9):1779-92. Doi: 10.1007\/s00424-013-1422-x.<\/li>\n
Mi\u00f1o G, Barriga R, Gutierrez G. (2014) Hydrogen Bonds And Heat Diffusion In \u0391-Helices: A Computational Study. The Journal Of Physical Chemistry B.\u00a0118(34):10025-34. Doi: 10.1021\/jp503420e.<\/li>\n
Moldenhauer H, Latorre R<\/strong><\/a>\u00a0Grandl J. (2014) The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-Methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole. PLoS One. 9(9):e106776. Doi: 10.1371\/journal.pone.0106776.<\/li>\n
Momboisse F, Olivares MJ, B\u00e1ez-Matus X, Guerra MJ, Flores-Mu\u00f1oz C,\u00a0S\u00e1ez JC<\/strong><\/a>, Mart\u00ednez AD<\/strong><\/a>\u00a0, C\u00e1rdenas AM<\/a><\/strong>. (2014)\u00a0Pannexin 1 channels: new actors in the regulation of catecholamine release from adrenal chromaffin cells.\u00a0Front Cell Neurosci.\u00a08:270. Doi: 10.3389\/fncel.2014.00270.<\/li>\n
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Neely A<\/strong><\/a>, Hidalgo P. (2014) Structure-function Of Proteins Interacting With The \u03911 Pore-forming Subunit Of High-voltage-activated Calcium Channels. Front Physiol. 5:209 Doi: 10.3389\/fphys.2014.00209.<\/li>\n
Negr\u00f3n-Oyarzo I, P\u00e9rez MA, Terreros G,\u00a0Munoz P, Dagnino-Subiabre A. (2014) Effects of Chronic Stress in Adolescence on Learned Fear, Anxiety, and Synaptic Transmission in the rat Prelimbic Cortex. Behav Brain Res.\u00a0259:342-53. Doi: 10.1016\/j.bbr.2013.11.001.<\/li>\n
Olivares MJ, Gonz\u00e1lez-Jamett AM<\/strong><\/a>, Guerra MJ, Baez-Matus X, Haro-Acu\u00f1a V, Mart\u00ednez-Quiles N, C\u00e1rdenas AM<\/a><\/strong>. (2014)\u00a0Src Kinases Regulate De Novo Actin Polymerization during Exocytosis in Neuroendocrine Chromaffin Cells. \u00a0PLoS One. 2014 9(6):e99001. Doi: 10.1371\/journal.pone.0099001.<\/li>\n
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Palacios-Munoz A, Escobar MJ, Vielma A, Araya J, Astudillo A, Garcia IE, Valdivia G, Hurtado J, Schmachtenberg O<\/a><\/strong>, Mart\u00ednez AD<\/strong><\/a>, Palacios AG<\/strong><\/a>\u00a0(2014)\u00a0Role Of Connexin Channels In The Retinal Light Response Of A Diurnal Rodent.\u00a0Frontiers In Cellular Neuroscience. 8:249. Doi: 10.3389\/fncel.2014.00249.<\/li>\n
Pantazis A, Savalli N, Sigg D,\u00a0Neely A<\/strong><\/a>, Olcese R. (2014)\u00a0Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proc Natl Acad Sci U S A. 111(51):18381-6. Doi: 10.1073\/pnas.1411127112<\/li>\n
Pezo D, Soudry D and Orio P<\/strong><\/a>\u00a0(2014). Diffusion approximation-based simulation of stochastic ion channels: which method to use?. Front. Comput. Neurosci. 8:139. Doi: 10.3389\/fncom.2014.00139.<\/li>\n
Pupo A, B\u00e1ez-Nieto D, Mart\u00ednez A<\/strong><\/a>, Latorre R<\/strong><\/a>,<\/strong> Gonzalez C<\/strong><\/a>\u00a0(2014)\u00a0Proton Channel Models: Filling The Gap Between Experimental Data And The Structural Rationale. Channels (Austin). 8(3):180-192. Doi: 10.4161\/chan.286658(3):180-192<\/li>\n
Pupo A,\u00a0Gonzalez Le\u00f3n C<\/a>.<\/strong> (2014) In pursuit of an inhibitory drug for the proton channel. Proc Natl Acad Sci U S A. 111(27):9673-4. Doi: 10.1073\/pnas.1408808111<\/li>\n
Raddatz N, Castillo JP, Gonzalez C<\/a><\/strong>\u00a0, Alvarez O, Latorre R<\/strong><\/a>\u00a0(2014) Temperature And Voltage Coupling To Channel Opening In Transient Receptor Potential Melastatin 8 (TRPM8). J Biol Chem. 289(51):35438-54 Doi: 10.1074\/jbc.M114.612713.<\/li>\n
Retamal MA, Alcayaga J, Bultynck G, Leybaer L, S\u00e1ez PJ, Fernandez R, Le\u00f3n LE and\u00a0S\u00e1ez JC<\/strong><\/a>\u00a0(2014)\u00a0Opening of pannexin and connexin based-channels increases the excitability of nodose ganglion sensory neurons.\u00a0Front. Cell. Neurosci. Front. Cell. Neurosci. 8:158. Doi: 10.3389\/fncel.2014.00158.<\/li>\n
Retamal MA,\u00a0S\u00e1ez JC<\/strong><\/a>\u00a0. (2014) Hemichannels; from the molecule to the function. Front Physiol. 5:411. Doi: 10.3389\/fphys.2014.00411.<\/li>\n
Retamal MJ, Cisternas MA, Gutierrez-Maldonado SE, P\u00e9rez-Acle T<\/a><\/strong>, Seifert B, Busch M, Huber P, Volkmann UG. (2014)\u00a0Towards Bio-silicon Interfaces: Formation Of An Ultra-thin Self-hydrated Artificial Membrane Composed Of Dipalmitoylphosphatidylcholine (DPPC) And Chitosan Deposited In High Vacuum From The Gas-phase. J Chem Phys. 141(10):104201.\u00a0Doi: 10.1063\/1.4894224.<\/li>\n
S\u00e1ez JC<\/strong><\/a>, Leybaert L. (2014) Hunting for connexin hemichannels. FEBS Lett. 588(8):1205-1211. Doi: 10.1016\/j.febslet.2014.03.004.<\/li>\n
S\u00e1ez PJ, Shoji KF, Aguirre A, S\u00e1ez JC<\/strong><\/a>. (2014) Regulation Of Hemichannels And Gap Junction Channels By Cytokines In Antigen-Presenting Cells. Mediators Inflamm. 2014:742734. Doi: 10.1155\/2014\/742734.<\/li>\n
Schramm OG, L\u00f3pez-Cort\u00e9s X, Santos LS, Laurie VF, Gonzalez-Nilo FD<\/a><\/strong>, Krolik M, Fischer R, Di Fiore S. (2014) pH-dependent nano-capturing of tartaric acid using dendrimers. Soft Matter. 10(4):600-8. Doi: 10.1039\/c3sm52255e.<\/li>\n
Shoji KF, S\u00e1ez PJ, Harcha P, Aguila HL,\u00a0S\u00e1ez JC. (2014)\u00a0Pannexin1 channels act downstream of P2X 7 receptors in ATP-induced murine T-cell death. \u00a0Channels (Austin). 8(2):142-56.<\/li>\n
Torres-Paz J, Whitlock KE<\/strong><\/a>\u00a0.\u00a0(2014) The olfactory sensory system develops from coordinated movements within the neural plate. Dev Dyn. 243(12):1619-31. Doi: 10.1002\/dvdy.24194.<\/li>\n
Torres YP, Granados ST, Latorre R<\/strong><\/a>\u00a0(2014) . Pharmacological consequences of the coexpression of BK channel \u03b1 and auxiliary \u03b2 subunits. Frontier in Physiology. 5:383 Doi: 10.3389\/fphys.2014.00383.<\/li>\n
Vielma AH, Agurto A, Valdes J, Palacios AG<\/strong><\/a>, Schmachtenberg O<\/strong><\/a>\u00a0(2014) Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells. PLoS One, 9(12):e114330. Doi: 10.1371\/journal.pone.0114330.<\/li>\n
White BH,\u00a0Ewer J<\/strong><\/a>. (2014)\u00a0Neural and Hormonal Control of Postecdysial Behaviors in Insects.\u00a0Annu Rev Entomol.\u00a059:363-81. Doi: 10.1146\/annurev-ento-011613-162028<\/li>\n
Whitlock KE<\/a>.<\/strong> (2014) Zebrafish Invade Valparaiso: Third Meeting and Symposium of the Latin American Zebrafish Network. Zebrafish. 11(6):580-582<\/li>\n
Whitlock KE<\/strong><\/a>. & Ciencia al Tiro, 2014, La alegria de la Ciencia, Andros Impresores, Santiago, Chile 118 p.<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2013″ tab_id=”2013″][vc_column_text 0=””]<\/p>\n
\n
Aguirre A, Maturana CJ, Harcha PA,\u00a0S\u00e1ez JC<\/a>.<\/strong> (2013) Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation. Mediators Inflamm. 2013:893521. Doi: 10.1155\/2013\/893521<\/li>\n
Aguirre A, Shoji KF,\u00a0 Saez JC<\/strong><\/a>, Henriquez M, Quest AFG. (2013) FasL-Triggered death of jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between fas and the purinergic receptor P2X7. Journal of Cellular Physiology 228 (2): 485\u2013493.\u00a0Doi: 10.1002\/jcp.24159<\/li>\n
Almeyda Campos MV, Costa C, Gonzalez C<\/strong><\/a>, Latorre R<\/a><\/strong>, Milesi V, Ferreira G. 2013. New biomedical and physiological knowledge of the sport (with emphasis on ion channels in skeletal muscle). In “New Technologies and Innovation in Human Movement.” (Book VI REMH). Ed. Universidad de Chihuahua.<\/li>\n
Ardiles A,\u00a0 Ewer J<\/strong><\/a>, Acosta ML, Kirkwood A, Mart\u00ednez A<\/strong><\/a>, Ebensperger \u00a0LA, Bozinovic \u00a0F, \u00a0Lee TM, Palacios AG<\/strong><\/a>. (2012). Octodon degus (Molina 1782): A model in comparative biology and biomedicine. Cold Spring Harbor Protocols. 2013(4): 312-18. Doi: 10.1101\/pdb.emo071357<\/li>\n
Baz\u00e1es A, Olivares J, Schmachtenberg O<\/strong><\/a>. (2013)\u00a0Properties, projections and tuning of teleost olfactory receptor neurons. Journal of Chemical Ecology. 39(4):451-64. Doi: 10.1007\/s10886-013-0268-1<\/li>\n
Boric K, Orio P<\/strong><\/a>, Vi\u00e9ville T, Whitlock KE<\/strong><\/a>\u00a0(2013). Quantitative analysis of cell migration using optical flow. PLOS One,8(7): e69574. Doi: 10.1371\/journal.pone.0069574.<\/li>\n
Castillo K, Valenzuela V, Matus S, Nassif M, O\u00f1ate M, Fuentealba Y, Encina G, Irrazabal T, Parsons G, Court FA, Schneider BL, Armentano D, Hetz C. (2013) Measurement of autophagy flux in the nervous system in vivo. Cell Death Dis. 14;4:e917. Doi: 10.1038\/cddis.2013.421<\/li>\n
Cea LA, Cisterna BA, Puebla C, Frank M, Figueroa XF, Cardozo C, Willecke K, Latorre R<\/strong><\/a>,\u00a0S\u00e1ez JC<\/a><\/strong>. (2013)\u00a0De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy.\u00a0Proc Natl Acad Sci U S A.\u00a0110(40):16229-34. Doi: 10.1073\/pnas.1312331110<\/li>\n
Cessac B and Palacios AG<\/strong><\/a>. (2013) Spike train statistics from empirical facts to theory: the case of the retina. In Mathematical Problems in Computational Biology and Biomedicine. Cazals F, Kornprobst P, Springer, pag. 261-302. Doi:10.1007\/978-3-642-31208-3_8<\/li>\n
Contreras GF, Castillo K, Enrique N, Carrasquel-Ursulaez W, Castillo JP, Milesi V,\u00a0Neely A<\/a><\/strong>, Alvarez O, Ferreira G, Gonzalez C<\/strong><\/a>, Latorre R<\/a>.<\/strong> (2013)\u00a0A BK (Slo1) channel journey from molecule to physiology.\u00a0Channels (Austin). 7(6): 441-457. Doi: 10.4161\/chan.26242<\/li>\n
Couve E, Osorio R and Schmachtenberg O<\/strong><\/a>.\u00a0(2013) The Amazing Odontoblast: Activity, Autophagy and Aging. J Dental Res.92(9):765-72. Doi: 10.1177\/0022034513495874<\/li>\n
Escobar MJ, Palacios AG<\/strong><\/a>. (2013). Beyond the retina neural coding: On Models and Neural Rehabilitation. Journal of Physiology Paris. 107(5):335-7.\u00a0Doi: 10.1016\/j.jphysparis.2013.08.002<\/li>\n
Escobar MJ, Pezo D, Orio P<\/strong><\/a>. (2013)\u00a0Mathematical analysis and modeling of motion direction selectivity in the retina. Journal of Physiology Paris. 107(5):349-59. Doi: 10.1016\/j.jphysparis.2013.08.003<\/li>\n
Figueroa XF, Lillo MA, Gaete PS, Riquelme M, S\u00e1ez JC<\/a>.<\/strong> (2013) Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels. Neuropharmacology. 75: 471\u2013478. Doi: 10.1016\/j.neuropharm.2013.02.022<\/li>\n
Figueroa V, S\u00e1ez PJ, Salas JD, Salas D, Jara O, Mart\u00ednez AD<\/strong><\/a>, Saez JC<\/a><\/strong> , Retamal MA. (2013) Linoleic acid induces opening of connexin26 hemichannels through a PI3K\/Akt\/Ca(2+)-dependent pathway. Biochim Biophys Acta. 1828(3):1169-79 . Doi: 10.1016\/j.bbamem.2012.12.006<\/li>\n
Giaume C, Froger N, Orellana JA, Retamal M and S\u00e1ez JC<\/strong><\/a>. (2013) Role of microglial activation in astroglial connexin expression and function leading to neurotoxicity”. Connexin cell communication channels: roles on the immune system and immunopathology (ed. Oviedo-Orta, Kwak and Evans). Taylor and Francis publisher. Pag 219-232.<\/li>\n
Giaume C, Leybaert L, C Naus C,\u00a0S\u00e1ez JC<\/a><\/strong>. (2013)\u00a0Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. Front Pharmacol. 2013;4:88. Doi: 10.3389\/fphar.2013.00088<\/li>\n
Gonzalez C<\/strong><\/a>, Rebolledo S, Perez M and Larsson HP. (2013) Molecular mechanism of voltage sensing in voltage-gated proton channels. Journal of General Physiology.\u00a0141(3):275-85.\u00a0Doi: 10.1085\/jgp.201210857<\/li>\n
Gonzalez-Jamett AM<\/strong><\/a>, \u00a0Momboisse F, Guerra MJ, Ory S, Baez-Matus X, Barraza N, Calco V, Houy S, Couve E,\u00a0Neely A<\/strong><\/a>, Mart\u00ednez A<\/a><\/strong>, Gasman S, C\u00e1rdenas AM<\/a><\/strong>\u00a0(2013) Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLOS ONE, 8(8):70638.<\/li>\n
Gonz\u00e1lez-Jamett AM<\/strong><\/a>, Momboisse F, Haro-Acu\u00f1a V, Bevilacqua JA, Caviedes P, C\u00e1rdenas AM<\/a><\/strong>. (2013)\u00a0Dynamin-2 Function and Dysfunction Along the Secretory Pathway.\u00a0Front Endocrinol (Lausanne). 2013 Sep 18;4:126. Doi: 10.3389\/fendo.2013.00126.<\/li>\n
Gonzalez-Jamett AM<\/strong><\/a>, \u00a0Momboisse F, Guerra MJ, Ory S, Baez-Matus X, Barraza N, Calco V, Houy S, Couve E,\u00a0Neely A<\/a>,<\/strong> Mart\u00ednez AD<\/strong><\/a>, Gasman S, C\u00e1rdenas AM<\/a><\/strong>\u00a0(2013) Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLOS ONE, 8(8):70638.\u00a0Doi: 10.1371\/journal.pone.0070638<\/li>\n
Hern\u00e1ndez-Salinas R, Vielma AZ, Arismendi MN, Boric MP, S\u00e1ez JC<\/strong><\/a>, Velarde V. (2013) Boldine Prevents Renal Alterations In Diabetic Rats. J Diabetes Res. 2013:593672. Doi: 10.1155\/2013\/593672<\/li>\n
Johnson RG,\u00a0S\u00e1ez JC<\/strong><\/a>. (2013) We\u2019ve Had Important Advances in the Connexin\/Pannexin Field, Yet There Is Still Much to Do Neuropharmacology. 75: 467\u2013470. Doi: 10.1016\/j.neuropharm.2013.08.011<\/li>\n
Kozoriz MG, Lai S, Vega JL, S\u00e1ez JC<\/strong><\/a>, Sin WC, Bechberger JF, Naus CC. (2013) Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia. Neuropharmacology.75 (2013) 549-556. Doi: 10.1016\/j.neuropharm.2013.05.003<\/li>\n
Latorre R<\/strong><\/a>. and B\u00e1ez-Nieto, D. (2013) Ca2+ activation of K+ channels: RCK domains. In: Encyclopedia of Biophysics. Springer Verlag. Gordon C.K. Roberts, editor. DOI 10.1007\/978-3-642-16712-6.<\/li>\n
Latorre R<\/strong><\/a>, Contreras G (2013)\u00a0Keeping you healthy: BK channel activation by omega-3 fatty acids. \u00a0Journal of General Physiology.\u00a0142:347-350. Doi: 10.1085\/jgp.201311100<\/li>\n
Latorre R<\/strong><\/a>, Gonzalez C<\/strong><\/a>, Rojas P. (2012) Signal-Transduction-Dependent Channels. Neuroscience in the 21st Century, Eugene Martin and Donald Pfaff, eds. Springer. 81-107. Doi: 10.1007\/978-1-4614-1997-6_5<\/li>\n
Latorre R<\/strong><\/a>, Morera FJ, Zaelzer C. \u00a0(2013). Voltage-dependent K+ channels. In: Encyclopedia of Biological Chemistry. 2nd Edition. Lane, M.D and \u00a0W.J. Lennarz, editors. Elsevier. Vol 1, pp. 399-404.
\nOcampo-Garc\u00e9s A, Hernandez F, Palacios AG<\/strong><\/a>. (2013). REM\u00a0sleep phase preference in the crepuscular Octodon degus assessed by selective REM sleep deprivation. Sleep.\u00a036(8):1247-56. Doi: 10.5665\/sleep.2896<\/li>\n
Orellana JA, Mart\u00ednez AD<\/strong><\/a>, Retamal MA. (2013) Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules. Neuropharmacology. 75: 567\u2013582<\/li>\n
Orellana JA, Velasquez S, Williams DW,\u00a0S\u00e1ez JC<\/strong><\/a>, Berman JW, Eugenin EA. (2013) Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes. J Leukoc Biol.\u00a094(3):399-407. Doi: 10.1189\/jlb.0512249<\/li>\n
Osorio R, Schmachtenberg O<\/strong><\/a>\u00a0(2013) Calcium-activated chloride channels do not contribute to the odorant transduction current in the marine teleost\u00a0Isacia conceptionis.\u00a0Journal of Fish Biology.\u00a083 (5):1468-73. Doi: 10.1111\/jfb.12253.<\/li>\n
Palacios AG<\/strong><\/a>, Lee TM. (2012). Husbandry and Breeding in the Octodon degus (Molina 1782).\u00a0 Cold Spring Harbor Protocols. 2013(4): 350-53. Doi: 10.1101\/pdb.prot073577
\nPastor P, Cisternas P, Salazar K, Silva-Alvarez C, Oyarce K, Jara N, Espinoza F, Mart\u00ednez AD<\/a><\/strong>\u00a0and Nualart F (2013) SVCT2 vitamin C transporter expression in progenitor cells of the postnatal neurogenic niche. Frontiers in Cellular Neuroscience. 7:119. Doi: 10.3389\/fncel.2013.00119<\/li>\n
Qiu F, Rebolledo S, Gonzalez C<\/strong><\/a>, Larsson HP. (2013) Subunit Interactions during Cooperative Opening of Voltage-Gated Proton Channels. Neuron. 77(2), 288\u201398. Doi: 10.1016\/j.neuron.2012.12.021.<\/li>\n
Ravanal MC, Alegr\u00eda-Arcos M, Gonzalez-Nilo FD<\/a><\/strong>, Eyzaguirre J. (2013)\u00a0Penicillium purpurogenum produces two GH family 43 enzymes with \u00df-xylosidase activity, one monofunctional and the other bifunctional: biochemical and structural analyses explain the difference. Arch Biochem Biophys. 540(1-2):117-2. Doi: 10.1016\/j.abb.2013.10.017<\/li>\n
Riquelme MA, Cea LA, Vega JL, Boric MP, Monyer H, Bennett MV, Frank M, Willecke K, S\u00e1ez JC<\/strong><\/a>. (2013) The ATP Required for Potentiation of Skeletal Muscle Contraction is released via Pannexin Hemichannels. Neuropharmacology. 75:594\u2013603. Doi: 10.1016\/j.neuropharm.2013.03.022.<\/li>\n
S\u00e1ez PJ, Orellana JA, Vega-Riveros N, Figueroa VA, Hern\u00e1ndez DE, Castro JF, Klein AD, Jiang JX, Zanlungo S,\u00a0S\u00e1ez JC<\/strong><\/a>. (2013) Disruption in connexin-based communication is associated with intracellular ca(2+) signal alterations in astrocytes from niemann-pick type C mice. PLoS One. 8(8):e71361.\u00a0Doi: 10.1371\/journal.pone.0071361<\/li>\n
S\u00e1ez PJ, Shoji KF, Retamal MA, Harcha PA, Ram\u00edrez G, Jiang JX, von Bernhardi R, S\u00e1ez JC<\/strong><\/a>. (2013) ATP is required and advances cytokine-induced gap junction formation in microglia in vitro. Mediators Inflamm. 2013:216402. Doi: 10.1155\/2013\/216402<\/li>\n
S\u00e1ez PJ, Shoji KF, S\u00e1ez JC<\/strong><\/a>. (2013) Gap Junctions in Antigen-Presenting Cells. In Connexin cell communication channels: roles on the immune system and immunopathology (ed. Oviedo-Orta, Kwak and Evans). Taylor and Francis publisher. pag 61-88. DOI: 10.1201\/b14166-14<\/li>\n
Soto-Liebe K, L\u00f3pez-Cort\u00e9s XA, Fuentes-Valdes JJ, Stucken K, Gonzalez-Nilo F<\/a><\/strong>, V\u00e1squez M. (2013) In silico analysis of putative paralytic shellfish poisoning toxins export proteins in cyanobacteria. PLoS One. 8(2):e55664. Doi: 10.1371\/journal.pone.0055664.<\/li>\n
Tricarico D, Mele A, Calzolaro S, Cannone G, \u00a0Camerino MG, Dinardo MM, Latorre R<\/strong><\/a>, Conte Camerino D. (2013) Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following \u00a0Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation. Plos One. 8(7). e69551. Doi: 10.1371\/journal.pone.0069551<\/li>\n
Vega JL, Subiabre M, Figueroa F, Schalper KA, Osorio L, Gonz\u00e1lez J,\u00a0S\u00e1ez JC<\/strong><\/a>. (2013) Role of Gap Junctions and Hemichannels in Parasitic Infections. Biomed Res Int. 2013:589130. Doi: 10.1155\/2013\/589130<\/li>\n
Vega-Zuniga T, Medina FS, Fredes F, Zuniga C, Sever\u00edn D, Palacios AG<\/strong><\/a>, Karten HJ, Mpodozis J. (2013). Does nocturnality drive binocular vision? Octodontine rodents as a case study. PlosOne. 8(12):e84199. Doi: 10.1371\/journal.pone.0084199<\/li>\n
Vergara-Jaque AP, Comer JR, Monsalve LF, Gonzalez-Nilo FD<\/a><\/strong>, Sandoval C. (2013) Computationally Efficient Methodology for Atomic-Level Characterization of Dendrimer-Drug Complexes: A Comparison of Amine- and Acetyl-Terminated PAMAM. Journal of Physical Chemistry B.\u00a0117(22):6801-13. Doi: 10.1021\/jp4000363<\/li>\n
Vilos C, Morales FA, Solar PA, Herrera NS, Gonzalez-Nilo FD<\/a><\/strong>, Aguayo DA, Mendoza HL, Comer J, Bravo ML, Gonzalez PA, Kato S, Cuello MA, Alonso C, Bravo EJ, Bustamante EI, Owen GI, Velasquez LA. (2013) Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells. Biomaterials. 34(16):4098-108. Doi: 10.1016\/j.biomaterials.2013.02.034<\/li>\n
Yang S, Megill A, Ardiles AO, Ransom S, Tran T, Koh MT, Lee HK, Gallagher M, Kirkwood A (2013) Integrity Of MGluR-LTD In The Associative\/commissural Inputs To CA3 Correlates With Successful Aging In Rats. J Neurosci.33(31):12670-8. Doi: 10.1523\/JNEUROSCI.1086-13.2013<\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2012″ tab_id=”2012″][vc_column_text 0=””]<\/p>\n
\n
Acu\u00f1a MA, P\u00e9rez-Nu\u00f1ez R, Noriega J, C\u00e1rdenas AM<\/a><\/strong>, Bacigalupo J, Delgado R, Arriagada C, Segura-Aguilar J, Caviedes R, Caviedes P. (2012) Altered voltage dependent calcium currents in a neuronal cell line derived from the cerebral cortex of a trisomy 16 fetal mouse, an animal model of down syndrome. Neurotoxicity Research. 22(1):59-68.<\/li>\n
Aguayo D, Gonzalez-Nilo F<\/a><\/strong>,\u00a0Chipot C. (2012) Insight into the properties of cardiolipin containing bilayers from molecular dynamics simulations, using a hybrid all-atom\/united-atom force field. Journal of Chemical Theory and Computation. 8(5):1765-1773.<\/li>\n
Ardiles AO, Tapia-Rojas CC, Mandal M, Alexandre F, Kirkwood A, Inestrosa NC & Palacios AG<\/strong><\/a>. (2012) Post-synaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer\u2019s disease. Proceedings of the National Academy of Science. 109(34):13835-40 .<\/li>\n
Avila-Salas, F ; Sandoval, C ; Caballero, J ; Guinez-Molinos, S ; Santos, LS ; Cachau, RE ; Gonzalez-Nilo FD<\/a><\/strong>\u00a0(2012) Study of Interaction Energies between the PAMAM Dendrimer and Nonsteroidal Anti-Inflammatory Drug Using a Distributed Computational Strategy and Experimental Analysis by ESI-MS\/MS JOURNAL OF PHYSICAL CHEMISTRY B 116 (7):2031-2039 DOI: 10.1021\/jp2069122<\/li>\n
Baz\u00e1es A. and Schmachtenberg O<\/strong><\/a>. (2012) Odorant tuning of olfactory crypt cells from juvenile and adult rainbow trout. Journal of Experimental Biology. 215(Pt 10):1740-8.
\nBennett MV, Garr\u00e9 JM, Orellana JA, Bukauskas FF, Nedergaard M,\u00a0S\u00e1ez JC<\/strong><\/a>. (2012) Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Research. 1487:3-15.<\/li>\n
Braidy N,\u00a0Munoz P, Palacios AG<\/strong><\/a>, Castellano-Gonz\u00e1lez G, Inestrosa NC, Chung RS, Sachdev P, Guillemin GJ. (2012) Recent animal models for Alzheimer\u2019s diseases: Clinical implications and basic research. Journal of Neural Transmission. 119(2):173-195.<\/li>\n
C\u00e1rdenas AM<\/a><\/strong>, Ardiles AO, Barraza N, Ba\u00e9z-Matus X, Caviedes P. (2013) Role of Tau Protein in Neuronal Damage in Alzheimer’s Disease and Down Syndrome. Archives of Medical Research.43(8):645-54.<\/li>\n
Cea LA, Riquelme MA, Cisterna BA, Puebla C, Vega JL, Rovegno M,\u00a0 S\u00e1ez JC<\/strong><\/a>. (2012) Connexin- and \u00a0annexin-based channels in normal skeletal muscles and their possible role in muscle atrophy. Journal of Membrane \u00a0Biology. 245(8):423-36.<\/li>\n
Contreras GF,\u00a0Neely A<\/strong><\/a>, Alvarez O, Gonzalez C<\/strong><\/a>, Latorre R<\/a><\/strong>. (2012) Modulation of BK channel voltage gating by different auxiliary \u03b2 subunits.\u00a0Proceedings of the National Academy of Sciences. 109(46):18991-6<\/li>\n
Cort\u00e9s C, Eugenin E, Aliaga E, Carre\u00f1o LJ, Bueno SM, Gonzalez PA, Gayol S,\u00a0Naranjo D, Noches V, Marassi MP, Rosenthal D, Jadue C, Ibarra P, Keitel C, Wohllk N, Court F, Kalergis AM, Riedel CA. (2012) Hypothyroidism in the adult rat causes incremental changes in brain-derived neurotrophic factor, neuronal and astrocyte apoptosis, gliosis, and deterioration of postsynaptic density. Thyroid.\u00a022(9):951-63.<\/li>\n
Couve, E., Osorio, O. and Schmachtenberg O<\/strong><\/a>. (2012) Mitochondrial autophagy and lipofuscin accumulation in aging odontoblasts. Journal of Dental Research. 91(7): 1-6.
\nDinardo MM, Camerino G, Mele A, Latorre R<\/strong><\/a>., Conte Camerino D, Tricarico D. (2012) Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle. Plos One, 7(7):e40235<\/li>\n
Eugenin EA, Basilio D,\u00a0S\u00e1ez JC<\/strong><\/a>, Orellana JA, Raine CS, Bukauskas F, Bennett MV, Berman JW. (2012) The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. Journal of Neuroimmune Pharmacology. 7(3):499-518.<\/li>\n
Fiori MC, Figueroa V, Zoghbi ME,\u00a0Saez JC<\/strong><\/a>, Reuss L, Altenberg GA.(2012) Permeation of calcium through purified connexin 26 hemichannels. Journal of \u00a0Biological Chemistry. 87(48): 40826-34<\/li>\n
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Gonzalez W, Riedelsberger J, Morales-Navarro SE, Caballero J, Alzate-Morales JH, Gonzalez-Nilo FD<\/a><\/strong>, Dreyer I. (2012) The ph-sensor of the plant K+ uptake channel Kat1 is built of a sensory cloud rather than of single key amino acids. Biochemical Journal. 442(1):57-63.<\/li>\n
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Jara O, Acu\u00f1a R, Garc\u00eda IE, Maripill\u00e1n J, Figueroa V,\u00a0S\u00e1ez JC<\/strong><\/a>, Araya-Secchi R, Lagos CF, P\u00e9rez-Acle T<\/a><\/strong>, Berthoud VM, Beyer EC, Mart\u00ednez AD<\/strong><\/a>. (2012) Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Molecular Biology of the Cell. 23(17):3299-3311.<\/li>\n
Koulakoff A, Mei X, Orellana JA,\u00a0S\u00e1ez JC<\/a>,<\/strong> Giaume C. (2012) Glial connexin expression and function in the context of Alzheimer\u2019s disease. Biochimica et Biophysica Acta. 1818(8):2048-2057.<\/li>\n
Lagos CF, Araya-Secchi R, Thomas P, P\u00e9rez-Acle T<\/a><\/strong>,<\/strong> Tapia RA, Salas CO. (2012) Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione. Journal of Molecular Modeling. 18(5):2055-64.<\/li>\n
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Maojo V, Fritts M, Martin-Sanchez F, De la Iglesia D, Cachau RE, Garcia-Remesal M, Crespo J, Mitchell JA, Anguita A, Baker N, Barreiro JM, Benitez SE, De la Calle G, Facelli JC, Ghazal P, Geissbuhler A, Gonzalez-Nilo F<\/a><\/strong>,\u00a0Graf N, Grangeat P, Hermosilla I, Hussein R, Kern J, Koch S, Legre Y, Lopez-Alonso V, Lopez-Campos G, Milanesi L, Moustakis V, Munteanu C, Otero P, Pazos A, Perez-Rey D, Potamias G, Sanz F, Kulikowski C. (2012) Nanoinformatics: developing new computing applications for nanomedicine.\u00a0Comput Sci Eng. 94(6):521-539.<\/li>\n
Miranda-Laferte E, Schmidt S, Jara AC,\u00a0 Neely A<\/strong><\/a>, Hidalgo P. (2012) A short polybasic segment between the two conserved domains of the \u03b22a-subunit modulates the rate of inactivation of R-type calcium channel. The Journal of Biological Chemistry.287(39):32588-97.<\/li>\n
Morera FJ, Alioua A, Kundu P, Salazar M,\u00a0Gonzalez, C, Mart\u00ednez AD<\/strong><\/a>, Stefani E, Toro L, Latorre R<\/strong><\/a>. (2012). The first transmembrane domain (TM1) of \u03b22-subunit binds to the transmembrane domain S1 of \u03b1-subunit in BK potassium channels. FEBS Letters. 586(16):2287-93.<\/li>\n
Moscoso C, Vergara-Jaque A, M\u00e1rquez-Miranda V, Sep\u00falveda R, Valencia I, Diaz-Franulic I<\/a><\/strong>, Gonzalez-Nilo F<\/a><\/strong>,\u00a0<\/strong>Naranjo D. (2012) K+ Conduction and Mg2+ Blockade in a Shaker Kv-Channel Single Point Mutant with an Unusually High Conductance. \u00a0Biophysical Journal, 103(6):1198-1207.<\/li>\n
Mu\u00f1oz P\u00a0(2012) Iron-mediated redox modulation in neural plasticity. Communicative & Integrative Biology 5:2,166\u2013168.<\/li>\n
Mu\u00f1oz P\u00a0and Humeres A. (2012) Iron deficiency on neuronal function. Biometals 25:825\u2013835.<\/li>\n
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Orellana JA, S\u00e1nchez HA, Schalper KA, Figueroa V,\u00a0 S\u00e1ez JC<\/strong><\/a>.\u00a0(2012) Regulation of intercellular calcium signaling through calcium interactions with connexin-based channels. Advances in Experimental Medicine and Biology.740:777-794.<\/li>\n
Orellana JA, von Bernhardi R, Giaume C, and\u00a0S\u00e1ez JC<\/strong><\/a>. (2012) Glial hemichannels and their involvement in aging and neurodegenerative diaseases. Reviews in Neuroscience. 23(2): 163\u2013177.<\/li>\n
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Orio P<\/a><\/strong>, Soudry D. (2012) Simple, fast and accurate implementation of the diffusion approximation algorithm for stochastic ion channels with multiple states. PLoS ONE. 7(5): e36670<\/li>\n
Perez-Armendariz EM, Cruz-Miguel L, Coronel-Cruz C, Esparza-Aguilar M, Pinzon-Estrada E, Rancano-Camacho E, Zacarias-Climaco G, Olivares PF, Espinosa AM, Becke, I,\u00a0Saez JC<\/a>,<\/strong> Berumen J, Perez-Palacios G. (2012) Connexin 36 is expressed in beta and connexins 26 and 32 in acinar cells at the end of the secondary transition of mouse pancreatic development and increase during fetal and perinatal life. Anatomical Record-Advances In Integrative Anatomy And Evolutionary Biology. 295(6): 980-990 .<\/li>\n
Pertusa M, Moldenhauer H, Brauchi S, Latorre R<\/strong><\/a>, Madrid R, Orio P<\/strong><\/a>\u00a0<\/strong>(2012). Mutagenesis and temperature-sensitive little machines. In: Mutagenesis, Mishra, R. Ed., InTech Open Access publisher. Chapter 11, pp 221-246.<\/li>\n
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[\/vc_column_text][\/vc_tta_section][vc_tta_section title=”2011″ tab_id=”2011″][vc_column_text 0=””]<\/p>\n
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Baez-Nieto, D., Castillo, JP., Dragicevic, C., Alvarez, O. and Latorre R<\/strong><\/a>. (2011) Thermo-TRP channels: Biophysics of polymodal receptors. Adv. Exp. Med. Biol. 704:469-490<\/li>\n
Brauchi S., Orio P<\/strong><\/a>. (2011) Voltage Sensing in ThermoTRP Channels. Adv.Exp. Med. Biol. 704:517-530.<\/li>\n
Castillo JP, De Giorgis D, Basilio D, Gadsby DC, Rosenthal JJ, Latorre R<\/a><\/strong>, Holmgren M, Bezanilla F<\/strong><\/a>. (2011) Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+\/K+-ATPase in the giant axon of the Humboldt squid. Proc Natl Acad Sci U S A. 108:20556-20561<\/li>\n
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Delgado, L.M. and Schmachtenberg O<\/strong><\/a>. (2011) Neurogenesis in the adult goldfish cerebellum. Anat Rec 294: 11-15.<\/li>\n
Gonzalez C<\/a>,<\/strong> Lopez Rogriguez A, Srikumar D, Rosenthal J & Holmgren M (2011) Editing of human KV1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. Nature Commun. Aug 16;2:436. doi: 10.1038\/ncomms1446<\/li>\n
Gonzalez C<\/strong><\/a>, Manzanares D, Ivonnet P, Chen RS, Valencia-Gattas M, Conner G.E, Larsson HP, & Salathe M *Contributed equally.(2011) Functional apical BK channels are required for maintenance of airway surface liquid volume. J. Biol. Chem. 286(22):19830-9.<\/li>\n
Grbic M, Van Leeuwen T, Clark RM, Rombauts S, Rouz\u00e9 P, Grbic V, Osborne EJ, Dermauw W, Ngoc PC, Ortego F, Hern\u00e1ndez-Crespo P, Diaz I, Martinez M, Navajas M, Sucena \u00c9, Magalh\u00e3es S, Nagy L, Pace RM, Djuranovic S, Smagghe G, Iga M, Christiaens O, Veenstra JA, Ewer J<\/strong><\/a>, Mancilla R, Villalobos RM, Hutter JL, Hudson SD, Velez M, Yi SV, Zeng J, Pires-daSilva A, Roch F, Cazaux M, Navarro M, Zhurov V, Acevedo G, Bjelica A, Fawcett JA, Bonnet E, Martens C, Baele G, Wissler L, Sanchez-Rodriguez A, Tirry L, Blais C, Demeestere K, Henz SR, Gregory TR, Mathieu J, Verdon L, Farinelli L, Schmutz J, Lindquist E, Feyereisen R, Van de Peer Y. (2011) The genome of Tetranychus urticae reveals herbivorous pest adaptations. Nature. 479(7374):487-92. doi: 10.1038\/nature10640.<\/li>\n
Latorre R<\/strong><\/a>, Brauchi S, Madrid R, Orio P<\/strong><\/a>. (2011) A cool channel in cold transduction. Physiology (Bethesda). Aug;26(4):273-85<\/li>\n
Mart\u00ednez AD<\/strong><\/a>, Maripill\u00e1n J, Acu\u00f1a R, Minogue PJ, Berthoud VM, Beyer EC (2011) Different domains are critical for oligomerization compatibility of different connexins Biochemical Journal 436: 35-43<\/li>\n
Miranda-Laferte, E,Gonzalez-Gutierrez, G, Schmidt, S ,Zeug, A, Ponimaskin, EG, Neely, A<\/strong><\/a>, Hidalgo, P (2011) Homodimerization of the Src Homology 3 Domain of the Calcium Channel beta-Subunit Drives Dynamin-dependent Endocytosis JOURNAL OF BIOLOGICAL CHEMISTRY Volume: 286(25): 22203-22210<\/li>\n
Mu\u00f1oz P, Humeres A., Elgueta C., Kirkwood A., Hidalgo C. and N\u00fa\u00f1ez M.T. (2011) Iron Mediates N-Methyl-D-aspartate Receptor-dependent Stimulation of Calcium-induced Pathways and Hippocampal Synaptic Plasticity. J. Biol. Chem. 286, (15): 13382-13392.<\/li>\n
Palacios AG<\/strong><\/a>, Cosmelli D, Cohen-Varela A. (2011). Un recorrido junto a Francisco Varela. Pag. 11-22. Edit. Adrian Palacios y Amy Cohen-Varela. La ciencia del ser: Las rutas de Francisco Varela. Editorial Universidad de Valparaiso. 320 p.<\/li>\n
Paul TA, Rovnak J, Quackenbush SL, Whitlock KE<\/strong><\/a>, Zhan H, Gong Z, Spitsbergen J, Paul R, Bowser PR, Casey JW. (2010). Transgenic expression of Walleye Dermal Sarcoma accessory genes in zebrafish does not result in tissue proliferation. Marine Biotechnology (NY). 13(2):142-50.<\/li>\n
Stephenson Jessica F.; Whitlock KE<\/strong><\/a>.; Partridge Julian C. (2011) Zebrafish Preference for Light or Dark Is Dependent on Ambient Light Levels and Olfactory Stimulation Zebrafish 8 (1): 17-22.<\/li>\n
Marcelo Salazar, Hans Moldenhauer and David Baez-Nieto. (2011) Could an Allosteric Gating Model Explain the Role of TRPA1 in Cold Hypersensitivity?. (Journal Club) The Journal of Neuroscience. 31(15):5554-5556\u00a0
\n<\/strong><\/li>\n<\/ol>\n
[\/vc_column_text][\/vc_tta_section][\/vc_tta_tabs][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"
[vc_row 0=””][vc_column css=”.vc_custom_1524844691130{background-color: #ffffff !important;}”][vc_row_inner][vc_column_inner 0=””][vc_column_text css=”.vc_custom_1638892709692{border-radius: 5px !important;}”] \u00a0 \u00a0Publications [\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row 0=””][vc_column el_class=”publicac”][vc_tta_tabs active_section=”1″][vc_tta_section title=”2026″ tab_id=”2026″][vc_column_text 0=””] Acosta ML, Zhang SX, Palacios AG (2026) Blood\u2013retinal biomarker integration for precision prevention of Alzheimer\u2019s disease: Lessons from retinal aging and the unfolded protein response. Neural Regen Res. doi: 10.4103\/NRR.NRR-D-25-01517 Caro JC, Bucchi C, Ponce N, Villena […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/pages\/24120"}],"collection":[{"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/comments?post=24120"}],"version-history":[{"count":827,"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/pages\/24120\/revisions"}],"predecessor-version":[{"id":52591,"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/pages\/24120\/revisions\/52591"}],"wp:attachment":[{"href":"https:\/\/cinv.uv.cl\/en\/wp-json\/wp\/v2\/media?parent=24120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}