Publicaciones

2018

  • Balboa E, Saavedra F, Cea LA, Vargas AA, Ramírez V, Escamilla R, Sáez JC, Regueira T. (2018). Sepsis-Induced Channelopathy in Skeletal Muscles is Associated with Expression of Non-Selective Channels. Shock. 2017 May 30. doi: 10.1097/SHK.0000000000000916. [Epub ahead of print]
  • Barría I, Güiza J, Cifuentes F, Zamorano P, Sáez JC, González J, Vega JL. (2018) Trypanosoma cruzi Infection Induces Pannexin-1 Channel Opening in Cardiac Myocytes. Am J Trop Med Hyg. 2017 Nov 6. doi: 10.4269/ajtmh.17-0293. [Epub ahead of print]
  • Castillo K, Diaz-Franulic I, Canan J, Gonzalez-Nilo F and Latorre R. (2018) Thermally-activated TRP channels: Molecular sensors for temperature detection. Phys. Biology. doi. org /10.1088/1478-3975/aa9a6f. [Epub ahead of print]
  • Couve, E., Lovera, M., Suzuki, K., Schmachtenberg O.  (2018) Schwann cell phenotypes in the aging human dental pulp. Dental Res. Oct 1:22034517733967. doi: 10.1177/0022034517733967. [Epub ahead of print]
  • Espinosa N, Alonso A, Morales C, Espinosa P, Chávez AE, Fuentealba P. (2018) Basal Forebrain Gating by Somatostatin Neurons Drives Prefrontal Cortical Activity. Cereb cortex. 2017 Nov 17:1-12. doi: 10.1093/cercor/bhx302. [Epub ahead of print]
  • García IE, Sánchez HA, Martinez AD, Retamal MA. (2018) Redox-mediated regulation of connexin proteins; focus on nitric oxide. Biochim Biophys Acta. 2017 Oct 7. pii: S0005-2736(17)30316-4. doi: 10.1016/j.bbamem.2017.10.006. [Epub ahead of print] Review
  • Marengo FD, Cárdenas AM. (2018) How does the stimulus define exocytosis in adrenal chromaffin cells? Pflugers Arch. 2017 Aug 29. doi: 10.1007/s00424-017-2052-5. [Epub ahead of print] Review
  • Pérez-Acle T,, Fuenzalida I, Martin AJM, Santibañez R, Avaria R, Bernardin A, Bustos AM, Garrido D, Jonathan Dushoff, Liu JH. (2018) Stochastic simulation of multiscale complex systems with PISKaS: A rule-based approach. Biochem Biophys Res Commun. 2017 Nov 21. pii: S0006-291X(17)32317-3. doi: 10.1016/j.bbrc.2017.11.138. [Epub ahead of print]
  • Rovegno M, Sáez JC. (2018)Role of astrocyte connexin hemichannels in cortical spreading depression. Biochim Biophys Acta. 2017 Aug 29. pii: S0005-2736(17)30264-X. doi: 10.1016/j.bbamem.2017.08.014. [Epub ahead of print] Review.
  • Vilches F, Ravanal MC, Bravo-Moraga F, Gonzalez-Nilo D, Eyzaguirre J. (2018) Penicillium purpurogenum produces a novel endo-1,5-arabinanase, active on debranched arabinan, short arabinooligosaccharides and on the artificial substrate p-nitrophenyl arabinofuranoside. Carbohydr Res. 2017 Nov 26;455:106-113. doi: 10.1016/j.carres.2017.11.014. [Epub ahead of print]

2017

  • Agurto A, Vielma AH, Cadiz B, Couve E, Schmachtenberg O. (2017). NO Signaling in Retinal Bipolar Cells. Exp. Eye Res.161:30-35. doi: 10.1016/j.exer.2017.05.013
  • Ahumada C, Bahamondes C, Cerda CA, Silva RA, Cruz G, Moya PR, Sotomayor-Zárate R, Renard GM. (2017) Amphetamine treatment affects the extra-hypothalamic vasopressinergic system in a sex- and nucleus-dependent manner. J Neuroendocrinol. 29(4). doi: 10.1111/jne.12465
  • Alvarez O and Latorre R. 2017. The enduring legacy of the “constant-field equation” in membrane ion transport. J Gen Physiol. 2017 Oct 2;149(10):911-920. doi: 10.1085/jgp.201711839
  • Ardiles AO, Grabrucker AM, Scholl FG, Rudenko G, Borsello T. (2017). Molecular and Cellular Mechanisms of Synaptopathies.  Neural Plast. 2017:2643943. doi: 10.1155/2017/2643943
  • Asuaje A, Smaldini P, Martín P, Enrique N, Orlowski A, Aiello EA, Gonzalez León C, Docena G, Milesi V. (2017) The inhibition of voltage-gated H+ channel (HVCN1) induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis. Pflugers Arch. 469(2):251-261. doi: 10.1007/s00424-016-1928-0
  • Berna-Erro A, Izquierdo-Serra M, Sepúlveda RV, Rubio-Moscardo F, Doñate-Macián P, Serra SA, Carrillo-Garcia J, Perálvarez-Marín A, Gonzalez-Nilo F, Fernández-Fernández JM, Valverde MA (2017) Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel. Sci Rep. 7(1):10522. doi: 10.1038/s41598-017-11274-1
  • Calbiague VM, Olivares J, Olivares E, Schmachtenberg O, (2017) The Chilean Recluse Spider (Araneae: Sicariidae) Displays Behavioral Responses to Conspecific Odors, but Not to Several General Odorants. J Med Entomol. 54(5):1435-1439. doi: 10.1093/jme/tjx101
  • Cárdenas AM, Fernández-Olivares P, Díaz-Franulic I, González-Jamett AM, Shimahara T, Segura-Aguilar J, Caviedes R, Caviedes P. (2017) Knockdown of Myo-Inositol Transporter SMIT1 Normalizes Cholinergic and Glutamatergic Function in an Immortalized Cell Line Established from the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Human Trisomy 21 (Down Syndrome). Neurotox Res. 32(4):614-623. doi: 10.1007/s12640-017-9775-0
  • Castillo K, Valenzuela V, Oñate M and Hetz C. (2017) A molecular reporter for monitoring autophagic flux in nervous system in vivo. Methods in Enzymology 588:109-131. doi: 10.1016/bs.mie.2016.09.077
  • Charvériat M, Naus CC, Leybaert L, Sáez JC, Giaume C. (2017) Connexin-Dependent Neuroglial Networking as a New Therapeutic Target. Front Cell Neurosci. 2017 Jun 26;11:174. doi: 10.3389/fncel.2017.00174. eCollection 2017. Review.
  • Duran-Aniotz C, Cornejo V, Espinoza S, Ardiles AO, Medinas D, Salazar C, Foley A, Gajardo I, Thielen P, Iwawaki T, Scheper W, Soto C, Palacios AG, Hoozemans J, Hetz C. (2017) IRE1 Signaling exacerbates Alzheimer’s disease pathogenesis. Acta Neuropathologica. doi: 10.1007/s00401-017-1694-x
  • Escobar MJ, Alexandre F, Viéville T, Palacios AG. (2017). Rapid Prototyping for Bio–Inspired Robots. In Rapid Roboting: Recent Advances on 3D Printers and Robotics, Intelligent Systems, Control and Automation: Science and Engineering. 82: 1-34
  • Gajardo-Gómez R, Labra VC, Maturana CJ, Shoji KF, Santibañez CA, Sáez JC, Giaume C, Orellana JA. (2017) Cannabinoids prevent the amyloid β-induced activation of astroglial hemichannels: A neuroprotective mechanism. Glia. 65(1):122-137. doi: 10.1002/glia.23080
  • Giaume C, Sáez JC, Song W, Leybaert L, Naus CC. (2017) Connexins and pannexins in Alzheimer’s disease. Neurosci Lett. 2017 Sep 8. pii: S0304-3940(17)30740-1. doi: 10.1016/j.neulet.2017.09.006. [Epub ahead of print] Review.
  • González A, Ugarte G, Restrepo C, Herrera G, Piña R, Gómez-Sánchez JA, Pertusa M, Orio P, Madrid R. (2017) Role of the excitability brake potassium current IKD in cold allodynia induced by chronic peripheral nerve injury. Journal of Neuroscience. 37 (12) 3109-3126; doi: 10.1523/JNEUROSCI.3553-16.2017.
  • González A, Herrera G, Ugarte G, Restrepo C, Piña R, Pertusa M, Orio P, Madrid R. (2017) IKD Current in Cold Transduction and Damage-Triggered Cold Hypersensitivity. Adv Exp Med Biol. 2017;1015:265-277. doi: 10.1007/978-3-319-62817-2_14.
  • González LF, Henríquez-Belmar F, Delgado-Acevedo C, Cisternas-Olmedo M, Arriagada G, Sotomayor-Zárate R, Murphy DL, Moya PR. (2017) Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice. Biol Res. 50(1):29. doi: 10.1186/s40659-017-0138-3. PDF
  • González-Jamett AM , Guerra MJ , Olivares MJ , Haro-Acuña V , Baéz-Matus X , Vásquez-Navarrete J, Momboisse F , Martinez-Quiles N, Cárdenas AM. (2017). The F-Actin Binding Protein Cortactin Regulates the Dynamics of the Exocytotic Fusion Pore through its SH3 Domain. Front. Cell. Neurosci., 11:130. doi: 10.3389/fncel.2017.00130.
  • González-Jamett AM, Baez-Matus X, Olivares MJ, Hinostroza F, Guerra-Fernández MJ, Vasquez-Navarrete J, Thao Bui M, Guicheney P, Romero NB, Bevilacqua JA, Bitoun M, Caviedes P, Cárdenas AM. (2017).  Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells. Scientific Reports. 7(1):4580. doi: 10.1038/s41598-017-04418-w
  • Hashimotodani Y, Nasrallah K, Jensen KR, Chávez AE, Carrera D, Castillo PE. (2017) LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance. Neuron. 95(4):928-943.e3. doi: 10.1016/j.neuron.2017.07.028.
  • Latorre R, Castillo K, Carrasquel-Ursulaez W, Sepulveda RV, Gonzalez-Nilo F, Gonzalez C and Alvarez O. (2017). Molecular determinants of BK channel functional diversity and functioning. Physiological Reviews, 97(1):39-87
  • Manzanares D, Araya-Durán I, Gallego-Yerga L, Játiva P, Márquez-Miranda V, Canan J, Jiménez Blanco JL, Mellet CO, Gonzalez-Nilo FD, García Fernández JM, Ceña V. (2017) Molecular determinants for cyclo-oligosaccharide-based nanoparticle-mediated effective siRNA transfection. Nanomedicine (Lond). 12(13):1607-1621. doi: 10.2217/nnm-2017-0123
  • Márquez-Miranda V, Abrigo J, Rivera JC, Araya-Durán I, Aravena J, Simon F, Pacheco N, Gonzalez-Nilo FD, Cabello-Verrugio C (2017).  The complex of PAMAM-OH dendrimer with Angiotensin (1-7) prevented the disuse-induced skeletal muscle atrophy in mice. Int J Nanomedicine. 12:1985-1999. doi: 10.2147/IJN.S125521
  • Márquez-Miranda V, Araya-Durán I, Gonzalez-Nilo FD. (2017). Multiescale molecular simulations applied to nucleic acid- dendrimer interactions studies. Curr Pharm Des. 23(21):3062-3075. doi: 10.2174/1381612823666170306093224.
  • Martin AJ, Contreras-Riquelme S, Dominguez C, Pérez-Acle T. (2017) LoTo: a graphlet based method for the comparison of local topology between gene regulatory networks. PeerJ. 5:e3052. doi: 10.7717/peerj.3052
  • Maturana CJ, Aguirre A, Sáez JC. (2017) High glucocorticoid levels during gestation activate the inflammasome in hippocampal oligodendrocytes of the offspring. Dev Neurobiol. 77(5):625-642. doi: 10.1002/dneu.22409. PDF
  • Muñoz PA, Márquez SL, Gonzalez-Nilo FD, Márquez-Miranda V, Blamey JM. (2017) Structure and application of antifreeze proteins from Antarctic bacteria. Microb Cell Fact. 16(1):138. doi: 10.1186/s12934-017-0737-2
  • Palacios AG, Escobar M J. and Céspedes E. (2017) Missing colors: The enactivist approach to perception. Constructivist Foundations. 13(1): 117–125. http://constructivist.info/13/1/117.
  • Palominos MF, Verdugo L, Gabaldon C, Pollak B, Ortíz-Severín J, Varas MA, Chávez FP, Calixto A. (2017) Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans. MBio. 2017 Oct 10;8(5). pii: e01234-17. doi: 10.1128/mBio.01234-17. PDF
  • Peñaloza JP, Márquez-Miranda V, Cabaña-Brunod M, Reyes-Ramírez R, Llancalahuen FM, Vilos C, Maldonado-Biermann F, Velásquez LA, Fuentes JA, Gonzalez-Nilo FD, Rodríguez-Díaz M, Otero C. (2017) Intracellular trafficking and cellular uptake mechanism of PHBV nanoparticles for targeted delivery in epithelial cell lines. J Nanobiotechnology. 3;15(1):1. doi: 10.1186/s12951-016-0241-6. PDF
  • Pinto BI, Pupo A, García IE, Mena-Ulecia K, Martínez AD, Latorre R, Gonzalez C. (2017) Calcium binding and voltage gating in Cx46 hemichannels. Sci Rep. 7(1):15851. doi: 10.1038/s41598-017-15975-5
  • Plotkin LI, Davis HM, Cisterna BA, Sáez JC. (2017) Connexins and Pannexins in Bone and Skeletal Muscle. Curr Osteoporos Rep. 15(4):326-334. doi: 10.1007/s11914-017-0374-z. Review
  • Puebla C, Retamal MA, Acuña R, Sáez JC. (2017) Regulation of Connexin-Based Channels by Fatty Acids. Front Physiol. 2017 Jan 24;8:11. doi: 10.3389/fphys.2017.00011. Review. PDF
  • Rubat S, Varas I, Sepúlveda R, Almonacid D, Gonzalez-Nilo F, Agosin E (2017) Increasing the intracellular isoprenoid pool in Saccharomyces cerevisiae by structural fine-tuning of a bifunctional farnesyl diphosphate synthase. FEMS Yeast Res. 17(4). doi: 10.1093/femsyr/fox032.
  • Sáez JC. (2017) Unraveling a novel mechanism for the up-regulation of connexin43 gap junctions between cells derived from the blood-brain barrier. J Physiol. 595(8):2411-2412. doi: 10.1113/JP274027
  • Sáez PJ, Vargas P, Shoji KF, Harcha PA, Lennon-Duménil AM, Sáez JC (2017) ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X7 receptors. Sci Signal. 10(506). pii: eaah7107. doi: 10.1126/scisignal.aah7107.
  • Sampogna-Mireles D, Araya-Durán ID, Márquez-Miranda V, Valencia-Gallegos JA, Gonzalez-Nilo FD (2017) Structural analysis of binding functionality of folic acid-PEG dendrimers against folate receptor. J Mol Graph Model. 72:201-208. doi:10.1016/j.jmgm.2017.01.004.
  • Selcho M, Millán C, Palacios-Muñoz A, Ruf F, Ubillo L, Chen J, Bergmann G, Ito C, Silva V, Wegener C, Ewer J.(2017). Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila. Nat Commun. 8:15563. doi: 10.1038/ncomms15563. PDF
  • Vargas AA, Cisterna BA, Saavedra-Leiva F, Urrutia C, Cea LA, Vielma AH, Gutierrez-Maldonado SE, Martin AJ, Pareja-Barrueto C, Escalona Y, Schmachtenberg O, Lagos CF, Pérez-Acle T, Sáez JC. (2017) On Biophysical Properties and Sensitivity to Gap Junction Blockers of Connexin 39 Hemichannels Expressed in HeLa Cells. Front Physiol. 9;8:38. doi: 10.3389/fphys.2017.00038. PDF
  • Vega-Zuniga T, Medina FS, Marín G, Letelier JC, Palacios AG, Němec P, Schleich CE, Mpodozis J. (2017) Selective binocular vision loss in two subterranean caviomorph rodents: Spalacopus cyanus and Ctenomys talarum. Sci Rep. 2;7:41704. doi: 10.1038/srep41704. PDF
  • Villanelo F, Escalona Y, Pareja-Barrueto C, Garate JA, Skerrett IM, Pérez-Acle T (2017) Accessing gap-junction channel structure-function relationships through molecular modeling and simulations. BMC Cell Biol. 17;18(Suppl 1):5. doi: 10.1186/s12860-016-0121-9. PDF
  • Xu K., Maidana JP, Caviedes M, Quero D, Aguirre P and Orio P. (2017). Hyperpolarization-activated current induces period-doubling cascades and chaos in a cold thermoreceptor model. Front Comp Neurosci,11:12. doi: 10.3389/fncom.2017.00012. PDF
  • Yi C, Ezan P, Fernández P, Schmitt J, Sáez JC, Giaume C, Koulakoff A. (2017) Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer’s disease. Glia. 65(10):1607-1625. doi: 10.1002/glia.23182
  • Zhong G, Akoum N, Appadurai DA, Hayrapetyan V, Ahmed O, Martinez AD, Beyer EC, Moreno AP. (2017) Mono-Heteromeric Configurations of Gap Junction Channels Formed by Connexin43 and Connexin45 Reduce Unitary Conductance and Determine both Voltage Gating and Metabolic Flux Asymmetry. Front Physiol. 8:346. doi: 10.3389/fphys.2017.00346. eCollection 2017.

2016

  • Acevedo W, Gonzalez-Nilo D, Agosin E. (2016) Docking and Molecular Dynamics of Steviol Glycoside-Human Bitter Receptor Interactions. J Agric Food Chem. 64(40):7585-7596. PDF
  • Aliaga C, Bravo-Moraga F, Gonzalez-Nilo D, Márquez S, Lühr S, Mena G, Rezende MC. (2016) Location of TEMPO derivatives in micelles: subtle effect of the probe orientation. Food Chem. Feb 1;192:395-401
  • Aspé-Sánchez M, Moreno M, Rivera MI, Rossi A and Ewer J. (2016) Oxytocin and vasopressin receptor gene polymorphisms: role in social and psychiatric trait. Frontiers in Neuroscience 28;9:510. doi: 10.3389/fnins.2015.00510 PDF
  • Boetsch C, Aguayo-Villegas DR, Gonzalez-Nilo FD, Lisa ÁT, Beassoni PR. (2016) Putative binding mode of Escherichia coli exopolyphosphatase and polyphosphates based on a hybrid in silico/biochemical approach. Arch Biochem Biophys. 606:64-72. doi: 10.1016/j.abb.2016.07.005. PDF
  • Bousquet F, Chauvel I, Flaven-Pouchon J, Farine JP, Ferveur JF. (2016) Dietary rescue of altered metabolism gene reveals unexpected Drosophila mating cues. J Lipid Res. 2016 Mar;57(3):443-50. doi: 10.1194/jlr.M064683. PDF
  • Calfún C, Domínguez C, Pérez-Acle T, Whitlock KE. (2016) Changes in Olfactory Receptor Expression Are Correlated With Odor Exposure During Early Development in the zebrafish (Danio rerio). Chem Senses. 1861(5):439-48. PDF
  • Cárdenas AM, González-Jamett AM, Cea LA, Bevilacqua JA, Caviedes P. (2016) Dysferlin function in skeletal muscle: Possible pathological mechanisms and therapeutical targets in dysferlinopathies. Exp Neurol. 283(Pt A):246-254. doi: 10.1016/j.expneurol.2016.06.026.Review. PDF
  • Cárdenas AM, Marengo F. (2016) How the stimulus defines the dynamics of vesicle pool recruitment, fusion mode and vesicle recycling in neuroendocrine cells. J Neurochem. 137(6):867-79. doi: 10.1111/jnc.13565. PDF
  • Castillo JP, Sánchez-Rodríguez JE, Clark Hyde H, Zaelzer CA, Aguayo D, Sepúlveda R, Luk LYP, Kent S, Gonzalez-Nilo F, Bezanilla F, and Latorre R. (2016) β1 Subunit-Induced Structural Rearrangements of the Ca2+- and Voltage-Activated K+ (BK) Channel. Proc. Natl Acad Sci (USA). 113(23):E3231-9. doi: 10.1073/pnas.1606381113. PDF
  • Cea LA, Balboa E, Puebla C, Vargas AA, Cisterna BA, Escamilla R, Regueira T, Sáez JC. (2016) Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels. Biochim Biophys Acta. 1862(10):1891-9. doi: 10.1016/j.bbadis.2016.07.003. PDF
  • Cea LA, Bevilacqua JA, Arriagada C, Cárdenas AM, Bigot A, Mouly V, Sáez JC, Caviedes P. (2016) The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes. BMC Cell Biol. May 24;17 Suppl 1:15. doi: 10.1186/s12860-016-0096-6. PDF
  • Cea LA, Puebla C, Cisterna BA, Escamilla R, Vargas AA, Frank M, Martínez-Montero P, Prior C, Molano J, Esteban-Rodríguez I, Pascual I, Gallano P, Lorenzo G, Pian H, Barrio LC, Willecke K, Sáez JC. (2016) Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis. Cell Mol Life Sci. 73(13):2583-99. doi: 10.1007/s00018-016-2132-2. PDF
  • Chávez Andrés E. (2016) ¿Cómo afecta el color al comportamiento?: Una mirada a la visón ultravioleta en mamíferos. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 21-24. PDF
  • Chetty S, Bhakat S, Martin AJ, Soliman ME. (2016) Multi-drug resistance profile of PR20 HIV-1 protease is attributed to distorted conformational and drug binding landscape: molecular dynamics insights. J Biomol Struct Dyn. 2016 Jan;34(1):135-51. PDF
  • Cisterna BA, Vargas AA, Puebla C, Sáez JC. 2016) Connexin hemichannels explain the ionic imbalance and lead to atrophy in denervated skeletal muscles. Biochim Biophys Acta. 1862(11):2168-2176. doi: 10.1016/j.bbadis.2016.08.020. PDF
  • Diao, F., Mena. W., Shi, J., Park, D., Diao, F., Taghert, P., Ewer J., and White, B.H. (2016) The splice Isoforms of the Drosophila Ecdysis Triggering Hormone receptor have developmentally distinct roles. Genetics. 202(1):175-89. PDF
  • Díaz J, Woudt L, Suazo L, Garrido C, Caviedes P, Cárdenas AM, Castiglioni C, Bevilacqua JA. (2016) Broadening The Imaging Phenotype of Dysferlinopathy at Different Disease Stages. Muscle Nerve. 54(2):203-10. doi: 10.1002/mus.25045. PDF
  • Diaz-Franulic I, Caceres-Molina J, Sepúlveda RV, Gonzalez-Nilo F, and Latorre R (2016) Structurally driven pharmacology pf transient receptor potential vanilloid1 (TRPV1) channel. Mol Pharmacol Sep;90(3):300-8. doi: 10.1124/mol.116.104430. PDF
  • Diaz-Franulic I, Poblete H, Miño G, Gonzalez C, and Latorre R (2016) Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels Ann. Rev. Biophys. 45:371-98. doi: 10.1146/annurev-biophys-062215-011034. PDF
  • English NJ and Garate JA (2016) Near-microsecond human aquaporin 4 gating dynamics in static and alternating external electric elds: Non-equilibrium molecular dynamics. J Chem Phys. 145(8):085102. doi: 10.1063/1.4961072. PDF
  • Escalona Y, Garate JA, Araya-Secchi R, Huynh T, Zhou R, Pérez-Acle T. (2016) Exploring the Membrane Potential of Simple Dual-Membrane Systems as Models for Gap-Junction Channels. Biophys J. Jun 21;110(12):2678-88. doi: 10.1016/j.bpj.2016.05.005. PDF
  • Ewer J. (2016) Como elegir un horario para Chile. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 9-13. PDF
  • Fernández A, Pupo A, Mena-Ulecia K and Gonzalez C, (2016) Pharmacological modulation of proton channel Hv1 in cancer therapy: Future perspectives Mol Pharmacol Sep;90(3):385-402. doi: 10.1124/mol.116.103804 PDF
  • Flaven-Pouchon J, Farine JP, Ewer J, Ferveur JF.(2016) Regulation of cuticular hydrocarbon profile maturation by Drosophila tanning hormone, bursicon, and its interaction with desaturase activity. Insect Biochem Mol Biol. 79:87-96. doi: 10.1016/j.ibmb.2016.10.007. PDF
  • Garate JA, Pérez-Acle T. (2016) From dimers to collective dipoles: Structure and dynamics of methanol/ethanol partition by narrow carbon nanotubes. J Chem Phys. 2016 Feb 14;144(6):064105. PDF
  • García IE, Bosen F, Mujica P, Pupo A, Flores-Muñoz C, Jara O, Gonzalez C, Willecke K and Martinez AD (2016) From Hyperactive Connexin26 Hemichannels to Impairments in Epidermal Calcium Gradient and Permeability Barrier in the Keratitis-Ichthyosis-Deafness Syndrome J Invest Dermatol 136(3):574-83. PDF
  • García IE, Prado P, Pupo A, Jara O, Rojas-Gómez D, Mujica P, Flores-Muñoz C, González-Casanova J, Soto-Riveros C, Pinto BI, Retamal MA, Gonzalez C and Martinez AD (2016) Connexinopathies: a structural and functional glimpse. BMC Cell Biology May 24;17 Suppl 1:17. doi: 10.1186/s12860-016-0092-x PDF
  • Graham Z, Collier L, QinW, Peng Y, Sáez JC , Bauman WA and Christopher Cardozo J. (2016) A soluble activin receptor IIB fails to prevent muscle atrophy in a mouse model of spinal cord injury. J Neurotrauma. 33(12):1128-35. doi: 10.1089/neu.2015.4058. PDF
  • Johnson RG, Le HC, Evenson K, Loberg SW, Myslajek TM, Prabhu A, Manley AM, O’Shea C, Grunenwald H, Haddican M, Fitzgerald PM, Robinson T, Cisterna BA, Sáez JC, Liu TF, Laird DW, Sheridan JD. (2016) Connexin Hemichannels: Methods for Dye Uptake and Leakage. J Membr Biol. 249(6):713-741. PDF
  • Krick S, Wang J, St-Pierre M, Gonzalez C, Dahl G, Salathe M. (2016) Dual Oxidase 2 (Duox2) Regulates Pannexin 1-mediated ATP Release in Primary Human Airway Epithelial Cells via Changes in Intracellular pH and Not H2O2 Production. J Biol Chem. 291(12):6423-32. doi: 10.1074/jbc.M115.664854. PDF
  • Lions S, Peña M (2016) Reading Comprehension in Latin America: Difficulties and Possible Interventions. New Dir Child Adolesc Dev. 2016(152):71-84. doi: 10.1002/cad.20158. PDF
  • Márquez-Miranda V, Araya-Durán I, Camarada MB, Comer J, Valencia-Gallegos JA, Gonzalez-Nilo F. (2016) Self-Assembly of Amphiphilic Dendrimers: The Role of Generation and Alkyl Chain Length in siRNA Interaction. Sci Rep. 2016 Jul 5;6:29436. doi: 10.1038/srep29436. PDF
  • Márquez-Miranda V, Peñaloza JP, Araya-Durán I, Reyes R, Vidaurre S, Romero V, Fuentes J, Céric F, Velásquez L, Gonzalez-Nilo F, Otero C. (2016) Effect of Terminal Groups of Dendrimers in the Complexation with Antisense Oligonucleotides and Cell Uptake. Nanoscale Res Lett. 11(1):66. doi: 10.1186/s11671-016-1260-9 PDF
  • Marracino P, Liberti M, Trapani E, Burnham CJ, Avena M, Garate JA, Apollonio F, English NJ. (2016) Human Aquaporin 4 Gating Dynamics under Perpendicularly-Oriented Electric-Field Impulses: A Molecular Dynamics Study. Int J Mol Sci. 2016 Jul 14;17(7). pii: E1133. doi: 10.3390/ijms17071133. PDF
  • Martin AJ, Dominguez C, Contreras-Riquelme S, Holmes DS, Pérez-Acle T.. (2016) Graphlet Based Metrics for the Comparison of Gene Regulatory Networks. PLoS One. 11(10):e0163497. doi: 10.1371/journal.pone.0163497. PDF
  • Martinez AD, Jara O, Ceriani R, Maripillán J, Mujica P, García IE (2016) Methods to determinate formation of heteromeric hemichannels. Chapter in : Gap Junction Channels and Hemichannels, BaiDonglin, and Sáez JC, Eds. Taylor and Francis Group. P 239–252. Book Chapter.
  • Martínez G, Vidal RL, Mardones P, Serrano FG, Ardiles AO, Wirth C, Valdés P, Thielen P, Schneider BK, Kerr B, Valdés JL, Palacios AG, Inestrosa NC, Glimcher LH, Hetz C. (2016). Regulation of memory formation by the transcription factor XBP1. Cell-Report. 14(6):1382-94. PDF
  • Mena W, Diegelmann S, Wegener C, Ewer J. (2016) Stereotyped responses of Drosophila peptidergic neuronal ensemble depend on downstream neuromodulators. Elife. 2016 Dec 15;5. pii: e19686. doi: 10.7554/eLife.19686
  • Moldenhauer H, Díaz-Franulic I , Gonzalez-Nilo F, Naranjo D(2016). Effective pore size and radius of capture for K+ ions in K-channels. Scientific Reports 6:19893 PDF
  • Moya-Díaz J, Álvarez JD, Montenegro M, Bayonés L, Belingheri AV, González-Jamett AM, Cárdenas AM, Marengo FD (2016) Sustained exocytosis after action potential-like stimulation at low frequencies in mouse chromaffin cells depends on a dynamin-dependent fast endocytotic process. Front Cell Neurosci. Jul 26;10:184. doi: 10.3389/fncel.2016.00184 PDF
  • Moya Vera PR. (2016) Interacciones genético-ambientales en el comportamiento. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 28-32. PDF
  • Muñoz P, Estay C, Díaz P, Elgueta C, Ardiles ÁO, Lizana PA (2016) Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats Neural Plast. 2016:4783836. doi: 10.1155/2016/4783836.
  • Naranjo D, Moldenhauer H, Pincuntureo M and Díaz-Franulic I (2016) Pore size matters for potassium channel conductance. J. Gen. Physiol.148(4):277-91. doi: 10.1085/jgp.201611625.
  • Olivares, J. (2016) Reseña bibliográfica sobre la araña de rincón (Loxosceles Laeta, Fam. Sicariirae): Que sabemos y que necesitamos saber. Anales Museo de Historia Natural de Valparaíso. Volumen 29, páginas 53-56. PDF
  • Park J, Chávez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, Tomita S. (2016) CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory. Neuron. 92(1):75-83. doi: 10.1016/j.neuron.2016.09.002
  • Pérez-Núñez R, Barraza N, Gonzalez-Jamett A, Cárdenas AM, Barnier JV, Caviedes P. (2016) Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in an In Vitro Neuronal Model of Down Syndrome: Consequences on Cell Process Formation and Extension. Neurotox Res. 30(1):76-87. doi: 10.1007/s12640-016-9613-9.
  • Pinto BI, García IE, Pupo A, Retamal MA, Martinez AD, Latorre R and Gonzalez C (2016) Charged residues at the first transmembrane region contribute to the voltage dependence of connexins slow gate. J Biol Chem 291(30):15740-52. doi: 10.1074/jbc.M115.709402
  • Puebla C, Cisterna BA, Salas DP, Delgado-López F, Lampe PD, Sáez JC. (2016) Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism. Biochim Biophys Acta. 1861(5):439-48
  • Qiu F, Chamberlin A, Watkins BM, Ionescu A, Perez ME, Barro-Soria R, González C, Noskov SY and Larsson HP (2016) Molecular mechanism of Zn2+ inhibition of a voltage-gated proton channel. Proc Natl Acad Sci U S A. 113(40):E5962-E5971
  • Retamal MA, García IE, Pinto B, Pupo A, Baez-Nieto D, Stehberg J, Del Rio R, Gonzalez C. (2016) Extracellular cysteine in connexins: role as redox sensors. Front in Physiol Jan 28;7:1. doi: 10.3389/fphys.2016.00001. eCollection 2016 PDF
  • Sáez JC. (2016) Proceedings of the International Gap Junction Conference 2015. BMC Cell Biol. May 24;17 Suppl 1:18. doi: 10.1186/s12860-016-0097-5 PDF
  • Salazar C, Valdivia G, Ardiles AO, Ewer J, Palacios AG. (2016). Genetic variants associated with neurodegenerative Alzheimer disease in natural model. Biological Research. 49(1):14. Special Issue. PDF
  • Salvador-Morales C, Brahmbhatt B, Márquez-Miranda V, Araya-Duran I, Canan J, Gonzalez-Nilo F, Vilos C, Cebral J, Mut F, Lohner R, Leong B, Sundaresan G, Zweit J. (2016) Mechanistic Studies on the Self-Assembly of PLGA Patchy Particles and Their Potential Applications in Biomedical Imaging. Langmuir. 32(31):7929-42. doi: 10.1021/acs.langmuir.6b02177.
  • Savalli N, Pantazis A,Sigg D, Weiss JN, Neely A and Olcese R (2016) The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials J Gen Physiol. 148(2):147-59. doi: 10.1085/jgp.201611586.
  • Sepúlveda-Crespo D, Vacas-Córdoba E, Márquez-Miranda V, Araya-Durán I, Gómez R, Mata FJ, Gonzalez-Nilo FD, Muñoz-Fernández MÁ. (2016) Effect of Several HIV Antigens Simultaneously Loaded with G2-NN16 Carbosilane Dendrimer in the Cell Uptake and Functionality of Human Dendritic Cells. Dec 21;27(12):2844-2849. doi: 10.1021/acs.bioconjchem.6b00623.
  • Valdés J, Trachsel-Moncho L, Sahaboglu A, Trifunovic D, Miranda M, Ueffing M, Paquet-Durand F, Schmachtenberg O (2016). Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies. ALTEX. 33(4):459-464. doi: 10.14573/altex.1603111. PDF
  • Vielma, A.H. and Schmachtenberg O. Electrophysiological fingerprints of OFF bipolar cells in rat retina. Sci. Rep., Jul 26;6:30259. doi: 10.1038/srep30259 PDF
  • Wang H, Ardiles A, Yang S, Valdivia G, Baek M, Tran T, Posada-Duque R, Chuang YA, Palacios AG, Gallagher M, Worley P, Kirkwood A. (2016). Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the hippocampus. Journal of Neuroscience 3;36(5):1723-9. PDF

2015

  • Aguayo D, Pacheco N, Morales EH, Collao B, Luraschi R, Cabezas C, Calderón P, Gonzalez-Nilo F, Gil F, Calderón IL, Saavedra CP (2015) Hydrogen peroxide and hypochlorous acid influx through the major S. Typhimurium porin OmpD is affected by substitution of key residues of the channel. Arch Biochem Biophys. 568:38-45
  • Arias-Darraz L, Cabezas D, Colenso CK, ALegría-Arcos M, Bravo-Moraga F, Varas-Concha I, Almonacid DE, Madrid R, Brauchi S. (2015) A transient receptor potential ion channel in Chlamydomonas shares key features with sensory transduction-associated TRP channels in mammals. Plant Cell. 27(1):177-88
  • Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Pérez-Acle T, Skerrett IM (2015) Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32. J Biol Chem. 290(28):17074-84
  • Camarada MB, Márquez-Miranda V, Araya-Durán I, Yévenes A, Gonzalez-Nilo F. (2015) PAMAM G4 dendrimers as inhibitors of the iron storage properties of human L-chain ferritin.Phys Chem Chem Phys. 17(29):19001-11
  • Carrasquel-Ursulaez W, Contreras GF, Sepúlveda R, Aguayo D, Gonzalez-Nilo F, Gonzalez C and Latorre R. (2015) Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel.. J Gen Physiol. 145(1):61-74 PDF
  • Carrasquel-Ursulaez W, Moldenhauer H, Castillo JP, Latorre R & Alvarez O. (2015) Biophysical analysis of thermosensitive TRP channels with a special focus on the cold receptor TRPM8. Temperature. 2(2):188-200. PDF
  • Castillo, JP, Rui, H, Basilio, D, Das, A, Roux, B, Latorre R, Bezanilla, F, Holmgren, M. (2015). Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase. Nat Commun. 6:7622 PDF
  • Castillo K, Contreras GF, Pupo A, Torres Y, Neely A, Gonzalez C and Latorre R. (2015) Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels. Proc Natl Acad Sci U S A. 112(15):4809-14 PDF
  • Castillo K, Pupo A, Baez-Nieto D, Contreras G; Morera FJ, Neely A, Latorre R, Gonzalez C. (2015) Voltage-Gated Proton (Hv1) Channels, a Singular Voltage Sensing Domain. FEBS Letters . 589(22):3471-8
  • Cerquera A, Muñoz J, Araya J, Gómez O (2015) Registro de actividad eléctrica en la retina de una rata albina empleando una matriz de microelectrodos. Acta Biológica Colombiana. 20(3):37-46
  • Cortés-Campos C, Letelier J, Ceriani R, Whitlock KE. (2015) Zebrafish adult-derived hypothalamic neurospheres generate gonadotropin-releasing hormone (GnRH) neurons. Biol Open. 4(9):1077-86. PDF
  • Diao F, Ironfield H, Diao F, Luan H, Shropshire W, Ewer J, Marr E, Potter CJ, Landgraf M and White BH (2015) “Plug-and-Play Genetic Access to Drosophila Cell Types Using Exchangeable Exon Cassettes” Cell Reports. 10(8):1410-21 PDF
  • Díaz-Franulic, I., Sepúlveda R, Navarro-Quezada N, F. Gonzalez-Nilo FD and Naranjo D. (2015). Pore dimensions and the role of occupancy in unitary conductance of Shaker K-channels. The Journal of General Physiology. J Gen Physiol 146:133-146 PDF
  • Du LY, Chang LY, Ardiles AO, Tapia-Rojas C, Araya J, Inestrosa NC, Palacios AG, Acosta ML. (2015) Alzheimer’s disease-related protein expression in the retina of Octodon degus. PLoS One. 10(8):e0135499. PDF
  • Duran-Lara EF, Avila-Salas F, Galaz S, John A, Marican A, Gutierrez M, Nachtigall FM, Gonzalez-Nilo FD, Santos LS. (2015) Nano-Detoxification of Organophosphate Agents by PAMAM Derivatives. J Braz Chem Soc 26(3): 580-91
  • Durán-Lara EF, López-Cortés XA, Castro RI, Avila-Salas F, Gonzalez-Nilo FD, Laurie VF, Santos LS. (2015) Experimental and theoretical binding affinity between polyvinylpolypyrrolidone and selected phenolic compounds from food matrices. Food Chem. 168:464-70
  • Elgueta C, Vielma AH, Palacios AG and Schmachtenberg O. (2015) Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells. Front. Cell. Neurosci. 9:6 PDF
  • Ferreira G, Raddatz N, Lorenzo Y, Gonzalez C and Latorre R (2015) Biophysical and Molecular Features of Thermosensitive TRP Channels Involved in Sensory Transduction . Chapter in: TRP Channels in Sensory Transduction, R. Madrid, J. Bacigalupo (eds.). Springer International Publishing Switzerland
  • García IE, Maripillán J, Jara O, Ceriani R, Palacios-Muñoz A, Ramachandran J, Olivero P, Pérez-Acle T, Gonzalez C, Sáez JC Contreras JE, Martinez AD. (2015) Keratitis-Ichthyosis-Deafness syndrome-associated Cx26 mutants produce non-functional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43 J Invest Dermatol. 135(5):1338-47
  • Garcia-Elias A, Berna-Erro A, Rubio-Moscardo F, Pardo-Pastor C, Mrkonjić S, Sepúlveda RV, Vicente R, Gonzalez-Nilo F, Valverde MA. (2015) Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels. Structure. 23(8):1404-13
  • García-Puente Y, Prado-Gutiérrez P, Martínez-Montes E (2015) Time-frequency methods for studying non-stationary auditory responses. IFMBE Proceedings. 49: 540-543
  • García-Puente Y, Prado-Gutiérrez P, Martínez-Montes (2015) Evaluación de métodos para la estimación de la respuestaauditiva de seguimiento de la modulación. Revista CENIC Ciencias Biologicas. 46(2): 156-167
  • Harcha PA, Vargas A, Yi C, Koulakoff AA, Giaume C, Sáez JC . (2015) Hemichannels Are Required for Amyloid β-Peptide-Induced Degranulation and Are Activated in Brain Mast Cells of APPswe/PS1dE9 Mice. J Neurosci. 2015 Jun 24;35(25):9526-38 PDF
  • Inestrosa NC, Rios JA, Cisternas P, Tapia-Rojas C, Rivera D, Braidy N, Zolezzi JM, Godoy JA, Carvajal FJ, Ardiles AO, Bozinovic F, Palacios AG, Sachdev PS.(2015). Age progression of neuropathological markers in the brain of the Chilean rodent Octodon degus, a natural model of Alzheimer’s disease. Brain Pathology. 25(6):679-91
  • Kalinowska M, Chávez AE, Lutzu S, Castillo PE, Bukauskas FF, Francesconi A. Actinin-4 Governs Dendritic Spine Dynamics and Promotes their Remodeling by Metabotropic Glutamate Receptors. J Biol Chem. 290(26):15909-20
  • Krüger, E., Mena, W., Lahr, E.C., Johnson, E.C., and Ewer J. (2015). Genetic analysis of Eclosion Hormone action during Drosophila larval ecdysis. Development,142(24):4279-4287
  • Langenhan T, Barr MM, Bruchas MR, Ewer J,, Griffith LC, Maiellaro I, Taghert PH, White BH, Monk KR (2015) Model Organisms in G Protein-Coupled Receptor Research. Mol Pharmacol. 88(3):596-603
  • Leiva, V., Tejo, M., Guiraud, P., Schmachtenberg O., Orio P. and Marmolejo-Ramos, F. (2015) Modeling neural activity with cumulative damage distributions. Biological Cybernetics. 109(4-5):421-33
  • López-Cabaña ZE, Valdés O, Vergara CE, Camarada MB, Nachtigall FM, Gonzalez-Nilo FD, Santos LS (2015) Photophysical studies of the interactions of poly(amidoamine) generation zero (PAMAM G0) with copper and zinc ions. Journal of Luminescence 164:23-30
  • Márquez-Miranda V, Camarada MB, Araya-Durán I, Varas-Concha I, Almonacid DE, Gonzalez-Nilo F. (2015) Biomimetics: From Bioinformatics to Rational Design of Dendrimers as Gene Carriers. PLoS One. 10(9):e0138392 PDF
  • Miño-Galaz GA. (2015) Allosteric Communication Pathways and Thermal Rectification in PDZ‑2 Protein: A Computational Study J. Phys Chem B. 119(20):6179-89
  • Miño-Galaz GA, Gutierrez G (2015) Hydrogen bonds and asymmetrical heat diffusion in alpha helices. A computational analysis Chemical Physics Letters 635:16-22
  • Morales-Camilo N, Salas CO, Sanhueza C, Espinosa-Bustos C, Sepúlveda-Boza S, Reyes-Parada M, Gonzalez-Nilo F, Caroli Rezende M, Fierro A. (2015) Synthesis, biological evaluation and molecular simulation of chalcones and aurones as selective MAO-B inhibitors. Chem Biol Drug Des. 85(6):685-95
  • Morera FJ, Baez-Nieto D, Lorenzo Y, Castillo K, Pupo A, Vargas-Chacoff L and Gonzalez C (2015) Role of ion channels in salt secretion by atlantic salmon gills during acclimation to seawater. Physiological Mini Reviews, 8(1)
  • Morera FJ, Saravia J, Pontigo JP, Vargas-Chacoff L, Contreras GF, Pupo A, Lorenzo Y, Castillo K, Tilegenova C, Cuello LG, Gonzalez C. (2015) Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: new therapeutics opportunities as targets in human diseases. Pharmacol Res. Nov;101:56-64. Review
  • Naranjo D, Wen H and Brehm P (2015). Zebrafish CaV2.1 Calcium Channels Are Tailored for Fast Synchronous Neuromuscular Transmission. Biophysical Journal. 108(3):578-84 PDF
  • Olivares, E; Orio P. (2015) Mathematical Modeling of TRPM8 and the Cold Thermoreceptors. In: TRP Channels in Sensory Transduction. Madrid, R.; Bacigalupo, J.,editors. Springer International Publishing, 209-223
  • Olivares E, Salgado S, Maidana JP, Herrera G, Campos M, Madrid R and Orio P (2015). TRPM8-dependent dynamic response in a mathematical model of cold thermoreceptor. PLOS One 588(Pt 17):3141-8 PDF
  • Orellana JA, Moraga-Amaro R, Díaz-Galarce R, Rojas S, Maturana CJ, Stehberg J, Sáez JC . (2015) Restraint stress increases hemichannel activity in hippocampal glial cells and neurons. Front Cell Neurosci. 9:102. PDF
  • Poblete H, Oyarzún I, Olivero P, Comer J, Zuñiga M, Sepulveda RV, Báez-Nieto D, Gonzalez Leon C, Gonzalez-Nilo F, Latorre R. (2015) Molecular Determinants of Phosphatidylinositol 4,5Bisphosphate (PI(4,5)P2) Binding to Transient Receptor Potential V1 (TRPV1) Channels. J Biol Chem. 290(4):2086-98 PDF
  • Prado-Gutierrez P, Castro-Fariñas A, Morgado-Rodriguez L, Velarde-Reyes E, Martinez AD, Martínez-Montes E. (2015) Habituation of auditory steady state responses evoked by amplitude-modulated acoustic signals in rats. Audiology Research. 5(113):21-28 PDF
  • Retamal MA, Leon-Paravic CG, Ezquer M, Ezquer F, Del Rio R, Pupo A, Martinez AD, Gonzalez C (2015) Carbon Monoxide: A New Player in the Redox Regulation of Connexin Hemichannels. IUBMB Life. 67(6):428-37 PDF
  • Retamal MA., Reyes EP., García IE., Pinto B., Martinez AD., Gonzalez C (2015) Diseases associated with leaky hemichannels. Frontiers in Cellular Neuroscience. 9:267. PDF
  • Riquelme MA, Cea LA, Vega JL, Puebla C, Vargas AA, Shoji KF, Subiabre M, Sáez JC. (2015) Pannexin channels mediate the acquisition of myogenic commitment in C2C12 reserve cells promoted by P2 receptor activation. Front Cell Dev Biol. 3:25. PDF
  • Rivas-Aravena A, Fuentes Y, Cartagena J, Brito T, Poggio V, La Torre J, Mendoza H, Gonzalez-Nilo F, Sandino AM, Spencer E. (2015) Development of a nanoparticle-based oral vaccine for Atlantic salmon against ISAV using an alphavirus replicon as adjuvant. Fish Shellfish Immunol. 45(1): 157-166
  • Rovegno M, Soto PA, Sáez PJ, Naus CC, Sáez JC and von Bernhardi R. (2015) Connexin43 hemichannels mediate secondary cellular damage spread from the trauma zone to distal zones in astrocyte monolayers. Glia 63(7):1185-99
  • Sáez JC Cisterna BA, Vargas A, Cardozo CP. (2015) Regulation of pannexin and connexin channels and their functional role in skeletal muscles. Cell Mol Life Sci. 72(15):2929-35
  • Salas D, Puebla C, Lampe PD, Lavandero S, Sáez JC. (2015) Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition. Biochim Biophys Acta. 1852(7):1268-1277
  • Suzuki, K., Lovera, M., Schmachtenberg O. and Couve, E. Axonal Degeneration in Dental Pulp precedes Primary Teeth Exfoliation. J Dental Res. 94(10):1446-53
  • Talaverón R, Fernández P, Escamilla R, Pastor AM, Matarredona ER, Sáez JC (2015) Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells. Front Cell Neurosci Oct 13;9:411 PDF
  • Tindi JO, Chávez AE, Cvejic S, Calvo-Ochoa E, Castillo PE, Jordan BA. (2015) ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015 Jun 17;35(24):8986-96. doi: 10.1523/JNEUROSCI.4029-14.2015.
  • Valdés, J., Olivares, J., Ponce, D., and Schmachtenberg O (2015) Analysis of olfactory sensitivity in rainbow trout (Oncorhynchus mykiss) reveals their ability to detect lactic acid, pyruvic acid and four B-vitamins. Fish Physiol. Biochem., 41(4):879-85
  • Valdés O, Vergara CE, Camarada MB, Carrasco-Sánchez V, Nachtigall FM, Tapia J, Fischer R, Gonzalez-Nilo FD, Santos LS. (2015) Synthesis and characterization of an insoluble polymer based on polyamidoamine: Applications for the decontamination of metals in aqueous systems. J Environ Manage. 147:321-9.
  • Whitlock KE. (2015) The loss of scents: Do defects in olfactory sensory neuron development underlie human disease? Birth Defects Res C Embryo Today. 105(2):114-25

2014

  • Abarca F, Gutierrez-Maldonado SE, Parada P, Martinez P, Maass A and Pérez-Acle T (2014) Insights on the structure and stability of Licanantase: a trimeric acid-stable coiled-coil lipoprotein from Acidithiobacillus thiooxidans. Peer J. 2:e457. PDF
  • Araya-Secchi R, Pérez-Acle T , Seung-gu Kang, Huynh T, Bernardin A, Escalona Y, Gárate JA, Martinez AD, García IE, Sáez JC and Zhou R (2014) Characterization of a Novel Water Pocket Inside the Human Cx26 Hemichannel Structure. Biophysical Journal, 107:599-612. PDF
  • Ardiles AO, Flores-Muñoz C, Toro-Ayala G, Cárdenas AM, Palacios AG, Muñoz P, Fuenzalida M, Sáez JC, Martinez AD. (2014). Pannexin 1 regulates the bidirectional hippocampal synaptic plasticity in the adult mice. Front Cell Neurosci. 8:326 PDF
  • Arenas-Salinas M, Ortega-Salazar S, Gonzalez-Nilo FD, Pohl E, Holmes DS, Quatrini R. (2014) AFAL: a web service for profiling amino acids surrounding ligands in proteins. J Comput Aided Mol Des. 28(11):1069-76
  • Arenas-Salinas M, Townsend PD, Brito C, Marquez V, Marabolli V, Gonzalez-Nilo F, Matias C, Watt RK, López-Castro JD, Domínguez-Vera J, Pohl E, Yévenes A. (2014) The crystal structure of ferritin from Chlorobium tepidum reveals a new conformation of the 4-fold channel for this protein family. Biochimie. 106:39-47
  • Baez D, Raddatz N, Ferreira G, Gonzalez C, Latorre R.(2014) Gating of Thermally Activated Channels. In: Thermal Sensors. L. Islas and F. Qin. Eds. Current Topics in Membranes. 74:51-87
  • Bhakat S, Martin AJM and Soliman MES. “An integrated molecular dynamics, principal component analysis and residue interaction network approach reveals the impact of M184V mutation on HIV reverse transcriptase resistance to lamivudine”. Mol. BioSyst., 10(8):2215-2228, 2014
  • Brito C, Matias C, Gonzalez-Nilo FD, Watt RK, Yévenes A. (2014) The C-Terminal Regions Have an Important Role in the Activity of the Ferroxidase Center and the Stability of Chlorobium tepidum Ferritin. Protein J. 33(3):211-20. PDF
  • Cárdenas JP, Olivares G, Cabrera F, Alfaro R, Goya D, Samaniego H, Gibert J, Palacios AG. Redes complejas: un caso de estudio sobre la colaboración científica. En: Las Rutas de la complejidad. Bustos E, Marquet PA, Palacios AG Editores. Ediciones Instituto de Sistemas Complejos de Valparaíso, Valparaiso, Chile, 211p
  • Cea LA, Riquelme MA, Vargas AA, Urrutia C, Sáez JC,. (2014) Pannexin 1 channels in skeletal muscles. Front Physiol. 5:139. PDF
  • Chang LY, Lowe J, Ardiles A, Lim J, Grey AC, Robertson K, Danesh-Meyer H, Palacios AG, Acosta ML (2014). Alzheimer’s disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers. Alzheimer’s & Dementia. 10(2):251-261
  • Cisterna BA, Cardozo C and Sáez JC(2014) Neuronal involvement in muscular atrophy. Front. Cell. Neurosci. 10;8:405 PDF
  • Cornejo I, Andrini O, Niemeyer MI, Marabolí V, Gonzalez-Nilo FD, Teulon J, Sepúlveda FV, Cid LP. (2014) Identification and Functional Expression of a Glutamate- and Avermectin-Gated Chloride Channel from Caligus rogercresseyi, a Southern Hemisphere Sea Louse Affecting Farmed Fish. PLoS Pathog. 10(9):e1004402. PDF
  • Couve E, Osorio R, Schmachtenberg O (2014) Reactionary Dentinogenesis and Neuroimmune Response in Dental Caries. J Dent Res. 93(8):788-793 PDF
  • Ewer J, Jindra M (2014). Development and regulation: Departing from paradigms. Editorial overview: Curr. Op. Insect Sci. 1: vii-ix. Review
  • Figueroa VA, Retamal MA, Cea LA, Salas JD, Vargas AA, Verdugo CA, Jara O, Martinez AD and Sáez JC (2014) Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca2+ signaling in HeLa cells. Front. Cell. Neurosci. 8:265. PDF
  • Garate JA, Pérez-Acle T and Oostenbrink C (2014) On the thermodynamics of carbon nanotube single-file water loading: Free energy, Energy and Entropy calculations Phys. Chem. Chem. Phys. 16(11):5119-28.
  • González-Jamett AM, Haro-Acuña V, Momboisse F, Caviedes P, Bevilacqua JA, Cárdenas AM. (2014) Dynamin-2 in nervous system disorders. Journal of Neurochemistry. 128(2):210-23 PDF
  • Hernández G, Barrios Hernández CJ, Díaz G, Garcia Garino C, Nesmachnow S, Pérez-Acle T, Storti M, Vasquez (Editors) M. High Performance Computing. Communications in Computer and Information Science. First HPCLATAM – CLCAR Latin American Conference CARLA 2014. Springer-Verlag Berlin Heidelberg 2014. ISBN 978-3-662-45482-4
  • Jabba S, Goyal R, Sosa-Pagán JO, Moldenhauer H, Wu J, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J. (2014) Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six. Neuron. 82(5):1017-1031
  • Le HT, Sin WC, Lozinsky S, Bechberger J, Vega JL, Guo XQ, Sáez JC, Naus CC. (2014) Gap junction intercellular communication mediated by connexin43 in astrocytes is essential for their resistance to oxidative stress. J Biol Chem. 289(3):1345-54. 39.
  • Leiva A, Fuentes I, Bossel E, Urzua M, Mendez M, Pino M, Radic D, Márquez V, Gonzalez-Nilo FD (2014) Block Copolymers in the Synthesis of Gold Nanoparticles. Two New Approaches: Copolymer Aggregates as Reductants and Stabilizers and Simultaneous Formation of Copolymer Aggregates and Gold Nanoparticles. J. of Polymer Science, 2014. 52(21):3069–79.
  • Martín P, Moncada M, Enrique N, Asuaje A, Valdez Capuccino JM, Gonzalez C, Milesi V. (2014) Arachidonic acid activation of BKCa (Slo1) channels associated with the β 1 subunit in human vascular smooth muscle cells. Pflügers Archiv European Journal of Physiology 466(9):1779-92. PDF
  • Miño, G.; Barriga, R.; Gutierrez, G. (2014) Hydrogen Bonds and Heat Diffusion in α-Helices: A Computational Study. The Journal of Physical Chemistry. 118(34):10025-34
  • Moldenhauer H, Latorre R Grandl J. (2014) The pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-Methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole. PLoS One. 9 (9): e106776 PDF
  • Momboisse F, Olivares MJ, Báez-Matus X, Guerra MJ, Flores-Muñoz C, Sáez JC, Martinez AD , Cárdenas AM. (2014) Pannexin 1 channels: new actors in the regulation of catecholamine release from adrenal chromaffin cells. Front Cell Neurosci. 8:270. PDF
  • Monrás, J. P.; Collao, B.; Molina-Quiroz, R. C.; Pradenas, G. A.; Saona, L. A.; Durán-Toro, V.; Ordenes-Aenishanslins, N.; Venegas, F. A.; Loyola, D. E.; Bravo, D.; Calderón, P. F.; Calderón, I. L.; Vásquez, C. C.; Chasteen, T. G.; Lopez, D. A.; Pérez-Donoso, J. M. (2014) Microarray analysis of the Escherichia coli response to CdTe-GSH Quantum Dots: understanding the bacterial toxicity of semiconductor nanoparticles. BMC Genomics, 15(1):1099
  • Neely A, Hidalgo P. (2014) Structure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channels. Front Physiol. 5:209 PDF
  • Negrón-Oyarzo I, Pérez MA, Terreros G, Munoz P, Dagnino-Subiabre A. (2014) Effects of Chronic Stress in Adolescence on Learned Fear, Anxiety, and Synaptic Transmission in the rat Prelimbic Cortex. Behav Brain Res. 259:342-53
  • Olivares MJ, González-Jamett AM, Guerra MJ, Baez-Matus X, Haro-Acuña V, Martínez-Quiles N, Cárdenas AM. (2014) Src Kinases Regulate De Novo Actin Polymerization during Exocytosis in Neuroendocrine Chromaffin Cells. PLoS One. 9(6):e99001 PDF
  • Orellana JA, Sáez JC, Bennett MV, Berman JW, Morgello S, Eugenin EA. (2014) HIV increases the release of dickkopf-1 (DKK1) protein from human astrocytes by a Cx43 hemichannel-dependent mechanism. J Neurochem. 128(5):752-63
  • Palacios-Munoz A, Escobar MJ, Vielma A, Araya J, Astudillo A, Garcia I, Valdivia G, Hurtado J, Schmachtenberg O, Martinez AD, Palacios AG (2014) Role of Connexin Channels in the Retinal Light Response of a Diurnal Rodent. Frontiers in Cellular Neuroscience. 8:249 PDF
  • Pantazis A, Savalli N, Sigg D, Neely A, Olcese R. (2014) Functional heterogeneity of the four voltage sensors of a human L-type calcium channel. Proc Natl Acad Sci U S A. 111(51):18381-6
  • Pezo D, Soudry D and Orio P (2014). Diffusion approximation-based simulation of stochastic ion channels: which method to use?. Front. Comput. Neurosci. 8:139. PDF
  • Pupo A, Báez-Nieto D, Martinez A, Latorre R, Gonzalez C (2014) Proton channel models: Filling the gap between experimental data and the structural rationale. Channels (Austin). 8(3): 180-92. PDF
  • Pupo A, Gonzalez León C.(2014) In pursuit of an inhibitory drug for the proton channel. Proc Natl Acad Sci U S A. 11:27, 9673-74.
  • Raddatz N, Castillo JP, Gonzalez C , Alvarez O, Latorre R. (2014) Temperature and Voltage Coupling to Channel Opening in Transient Receptor Potential Melastatin 8 (TRPM8). J Biol Chem. 289(51):35438-54 PDF
  • Retamal MA, Alcayaga J, Bultynck G, Leybaer L, Sáez PJ, Fernandez R, León LE and Sáez JC (2014) Opening of pannexin and connexin based-channels increases the excitability of nodose ganglion sensory neurons. Front. Cell. Neurosci. 8:158 PDF
  • Retamal MA, Sáez JC . (2014) Hemichannels; from the molecule to the function. Front Physiol. 5:411. PDF
  • Retamal MJ, Cisternas MA, Gutierrez-Maldonado SE, Pérez-Acle T, Seifert B, Busch M, Huber P, Volkmann UG. (2014) Towards bio-silicon interfaces: Formation of an ultra-thin self-hydrated artificial membrane composed of dipalmitoylphosphatidylcholine (DPPC) and chitosan deposited in high vacuum from the gas-phase. J Chem Phys. 141(10):104201.
  • Sáez JC, Leybaert L. (2014) Hunting for connexin hemichannels. FEBS Lett. 588(8):1205-1211. Review.
  • Sáez PJ, Shoji KF, Aguirre A, Sáez JC. (2014) Regulation of Hemichannels and Gap Junction Channels by Cytokines in Antigen-Presenting Cells. Mediators Inflamm. 2014:742734. Review. PDF
  • Schramm OG, López-Cortés X, Santos LS, Laurie VF, Gonzalez-Nilo FD, Krolik M, Fischer R, Di Fiore S. (2014) pH-dependent nano-capturing of tartaric acid using dendrimers. Soft Matter. 10(4):600-8.
  • Shoji KF, Sáez PJ, Harcha P, Aguila HL, Sáez JC. (2014) Pannexin1 channels act downstream of P2X 7 receptors in ATP-induced murine T-cell death. Channels (Austin). 8(2):142-56.
  • Torres-Paz J, Whitlock KE (2014) Olfactory sensory system develops from coordinated movements within the neural plate. Dev Dyn. 243(12):1619-31
  • Torres YP, Granados ST, Latorre R (2014) . Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunits. Frontier in Physiology. 5:383 PDF
  • Vielma AH, Agurto A, Valdes J, Palacios AG, Schmachtenberg O (2014) Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells. PLoS One, 9(12):e114330
  • White BH, Ewer J. (2014) Neural and Hormonal Control of Postecdysial Behaviors in Insects. Annu Rev Entomol. 59:363-81 PDF
  • Whitlock KE. (2014) Zebrafish Invade Valparaiso: Third Meeting and Symposium of the Latin American Zebrafish Network. Zebrafish. 11(6):580-582
  • Whitlock KE.. & Ciencia al Tiro, 2014, La alegria de la Ciencia, Andros Impresores, Santiago, Chile 118 p.

2013

  • Aguirre A, Maturana CJ, Harcha PA, Sáez JC. (2013) Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation. Mediators Inflamm. 2013:893521 PDF
  • Aguirre A, Shoji KF, Saez JC, Henriquez M, Quest AFG. (2013) FasL-Triggered death of jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between fas and the purinergic receptor P2X7. Journal of Cellular Physiology 228 (2): 485–493. PDF
  • Almeyda Campos MV, Costa C, Gonzalez C, Latorre R, Milesi V, Ferreira G. 2013. New biomedical and physiological knowledge of the sport (with emphasis on ion channels in skeletal muscle). In “New Technologies and Innovation in Human Movement.” (Book VI REMH). Ed. Universidad de Chihuahua.
  • Ardiles A, Ewer J, Acosta ML, Kirkwood A, Martinez A, Ebensperger LA, Bozinovic F, Lee TM, Palacios AG. (2013). Octodon degus (Molina 1782): A model in comparative biology and biomedicine. Cold Spring Harbor Protocols. 2013(4): 312-18.
  • Bazáes A, Olivares J, Schmachtenberg O. (2013) Properties, projections and tuning of teleost olfactory receptor neurons. Journal of Chemical Ecology. 39(4):451-64.
  • Boric K, Orio P, Viéville T, Whitlock KE (2013). Quantitative analysis of cell migration using optical flow. PLOS One,8(7): e69574. PDF
  • Castillo K, Valenzuela V, Matus S, Nassif M, Oñate M, Fuentealba Y, Encina G, Irrazabal T, Parsons G, Court FA, Schneider BL, Armentano D, Hetz C. (2013) Measurement of autophagy flux in the nervous system in vivo. Cell Death Dis. 14;4:e917. PDF
  • Cea LA, Cisterna BA, Puebla C, Frank M, Figueroa XF, Cardozo C, Willecke K, Latorre R, Sáez JC. (2013) De novo expression of connexin hemichannels in denervated fast skeletal muscles leads to atrophy. Proc Natl Acad Sci U S A. 110(40):16229-34.
  • Cessac B and Palacios AG. (2013) Spike train statistics from empirical facts to theory: the case of the retina. In Mathematical Problems in Computational Biology and Biomedicine. Cazals F, Kornprobst P, Springer, pag. 261-302.
  • Contreras GF, Castillo K, Enrique N, Carrasquel-Ursulaez W, Castillo JP, Milesi V, Neely A, Alvarez O, Ferreira G, Gonzalez C, Latorre R. (2013) A BK (Slo1) channel journey from molecule to physiology. Channels (Austin). 7(6): 441-457.
  • Couve E, Osorio R and Schmachtenberg O. (2013) The Amazing Odontoblast: Activity, Autophagy and Aging. J Dental Res.92(9):765-72
  • Escobar MJ, Palacios AG. (2013). Beyond the retina neural coding: On Models and Neural Rehabilitation. Journal of Physiology Paris. 107(5):335-7
  • Escobar MJ, Pezo D, Orio P. (2013) Mathematical analysis and modeling of motion direction selectivity in the retina. Journal of Physiology Paris. 107(5):349-59
  • Figueroa XF, Lillo MA, Gaete PS, Riquelme M, Sáez JC. (2013) Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels. Neuropharmacology.75: 471–478. PDF
  • Figueroa V, Sáez PJ, Salas JD, Salas D, Jara O, Martínez AD, Sáez JC, Retamal MA. (2013) Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway. Biochim Biophys Acta. 1828(3):1169-79. PDF
  • Giaume C, Froger N, Orellana JA, Retamal M, Sáez JC. (2013) Impact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation. In Connexin cell communication channels: roles in the immune system and immunopathology (ed. Oviedo-Orta, Kwak and Evans). Taylor and Francis publisher. pag 219-232.
  • Giaume C, Leybaert L, C Naus C, Sáez JC. (2013) Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. Front Pharmacol. 2013;4:88. PDF
  • Gonzalez C, Rebolledo S, Perez M and Larsson HP. (2013) Molecular mechanism of voltage sensing in voltage-gated proton channels. Journal of General Physiology. 141(3):275-85. PDF
  • Gonzalez-Jamett AM, Momboisse F, Guerra MJ, Ory S, Baez-Matus X, Barraza N, Calco V, Houy S, Couve E, Neely A, Martínez AD, Gasman S, Cárdenas AM (2013) Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLOS ONE, 8(8):70638. PDF
  • González-Jamett AM, Momboisse F, Haro-Acuña V, Bevilacqua JA, Caviedes P, Cárdenas AM. (2013) Dynamin-2 Function and Dysfunction Along the Secretory Pathway. Front Endocrinol (Lausanne). 2013 Sep 18;4:126. PDF
  • Hernández-Salinas R, Vielma AZ, Arismendi MN, Boric MP, Sáez JC, Velarde V. (2013) Boldine prevents renal alterations in diabetic rats. J Diabetes Res. 2013:593672. PDF
  • Johnson RG, Sáez JC. (2013) “We’ve Had Important Advances in the Connexin/Pannexin Field, Yet There Is Still Much to Do” Neuropharmacology. 75: 467–470 PDF
  • Kozoriz MG, Lai S, Vega JL, Sáez JC, Sin WC, Bechberger JF, Naus CC. (2013) Cerebral ischemic injury is enhanced in a model of oculodentodigital dysplasia. Neuropharmacology. 75 (2013) 549-556. PDF
  • Latorre R and Báez-Nieto, D. (2013) Ca2+ activation of K+ channels: RCK domains. In: Encyclopedia of Biophysics. Springer Verlag. Gordon C.K. Roberts, editor. DOI 10.1007/978-3-642-16712-6
  • Latorre R, Contreras G (2013) Keeping you healthy: BK channel activation by omega-3 fatty acids. Journal of General Physiology. 142:347-350
  • Latorre R, Gonzalez C, Rojas P. (2013) Signal-Transduction-Dependent Channels. Neuroscience in the 21st Century, Eugene Martin and Donald Pfaff, eds. Springer. pp. 81-37
  • Latorre R, Morera FJ, Zaelzer C. (2013). Voltage-dependent K+ channels. In: Encyclopedia of Biological Chemistry. 2nd Edition. Lane, M.D and W.J. Lennarz, editors. Elsevier. Vol 1, pp. 399-404.
  • Ocampo-Garcés A, Hernandez F, Palacios AG. (2013). REM sleep phase preference in the crepuscular Octodon degus assessed by selective REM sleep deprivation. Sleep. 36(8):1247-56.
  • Orellana JA, Martinez AD, Retamal MA. (2013) Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules. Neuropharmacology. 75: 567–582. PDF
  • Orellana JA, Velasquez S, Williams DW, Sáez JC, Berman JW, Eugenin EA. (2013) Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes. J Leukoc Biol. 94(3):399-407.
  • Osorio R, Schmachtenberg O (2013) Calcium-activated chloride channels do not contribute to the odorant transduction current in the marine teleost Isacia conceptionis. Journal of Fish Biology. 83 (5):1468-73.
  • Palacios AG, Lee TM. (2013). Husbandry and Breeding in the Octodon degus (Molina 1782). Cold Spring Harbor Protocols. 2013(4): 350-53.
  • Pastor P, Cisternas P, Salazar K, Silva-Alvarez C, Oyarce K, Jara N, Espinoza F, Martínez AD and Nualart F (2013) SVCT2 vitamin C transporter expression in progenitor cells of the postnatal neurogenic niche. Frontiers in Cellular Neuroscience. 7:119. PDF
  • Qiu F, Rebolledo S, Gonzalez C, Larsson HP. (2013) Subunit Interactions during Cooperative Opening of Voltage-Gated Proton Channels. Neuron. 77(2), 288–98.
  • Ravanal MC, Alegría-Arcos M, Gonzalez-Nilo FD, Eyzaguirre J. (2013) Penicillium purpurogenum produces two GH family 43 enzymes with ß-xylosidase activity, one monofunctional and the other bifunctional: biochemical and structural analyses explain the difference. Arch Biochem Biophys. 540(1-2):117-24 PDF
  • Riquelme MA, Cea LA, Vega JL, Boric MP, Monyer H, Bennett MV, Frank M, Willecke K, Sáez JC. (2013) The ATP Required for Potentiation of Skeletal Muscle Contraction is released via Pannexin Hemichannels. Neuropharmacology. 75:594–603 PDF
  • Sáez PJ, Orellana JA, Vega-Riveros N, Figueroa VA, Hernández DE, Castro JF, Klein AD, Jiang JX, Zanlungo S, Sáez JC. (2013) Disruption in connexin-based communication is associated with intracellular ca(2+) signal alterations in astrocytes from niemann-pick type C mice. PLoS One. 8(8):e71361. PDF
  • Sáez PJ, Shoji KF, Retamal MA, Harcha PA, Ramírez G, Jiang JX, von Bernhardi R, Sáez JC. (2013) ATP is required and advances cytokine-induced gap junction formation in microglia in vitro. Mediators Inflamm. 2013:216402. PDF
  • Sáez PJ, Shoji KF, Sáez JC. (2013) Gap Junctions in Antigen-Presenting Cells. In Connexin cell communication channels: roles on the immune system and immunopathology (ed. Oviedo-Orta, Kwak and Evans). Taylor and Francis publisher. pag 61-88.
  • Soto-Liebe K, López-Cortés XA, Fuentes-Valdes JJ, Stucken K, Gonzalez-Nilo F, Vásquez M. (2013) In silico analysis of putative paralytic shellfish poisoning toxins export proteins in cyanobacteria. PLoS One. 8(2):e55664. PDF.
  • Tricarico D, Mele A, Calzolaro S, Cannone G, Camerino MG, Dinardo MM, Latorre R, Conte Camerino D. (2013) Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation. Plos One. 8(7). e69551. PDF
  • Vega JL, Subiabre M, Figueroa F, Schalper KA, Osorio L, González J, Sáez JC. (2013) Role of Gap Junctions and Hemichannels in Parasitic Infections. Biomed Res Int. 2013:589130. Review. PDF
  • Vega-Zuniga T, Medina FS, Fredes F, Zuniga C, Severín D, Palacios AG, Karten HJ, Mpodozis J. (2013). Does nocturnality drive binocular vision? Octodontine rodents as a case study. PlosOne. 8(12):e84199
  • Vergara-Jaque AP, Comer JR, Monsalve LF, Gonzalez-Nilo FD, Sandoval C. (2013) A Computationally Efficient Methodology for Atomic-Level Characterization of Dendrimer-Drug Complexes: A Comparison of Amine- and Acetyl-Terminated PAMAM. Journal of Physical Chemistry B. 117(22):6801-13.
  • Vilos C, Morales FA, Solar PA, Herrera NS, Gonzalez-Nilo FD, Aguayo DA, Mendoza HL, Comer J, Bravo ML, Gonzalez PA, Kato S, Cuello MA, Alonso C, Bravo EJ, Bustamante EI, Owen GI, Velasquez LA. (2013) Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells. Biomaterials. May. 34(16):4098-108. PDF
  • Yang S1, Megill A, Ardiles AO, Ransom S, Tran T, Koh MT, Lee HK, Gallagher M, Kirkwood A. (2013) Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats. J Neurosci. 33(31):12670-8

2012

  • Acuña MA, Pérez-Nuñez R, Noriega J, Cárdenas AM, Bacigalupo J, Delgado R, Arriagada C, Segura-Aguilar J, Caviedes R, Caviedes P. (2012) Altered voltage dependent calcium currents in a neuronal cell line derived from the cerebral cortex of a trisomy 16 fetal mouse, an animal model of down syndrome. Neurotoxicity Research. 22(1):59-68.
  • Aguayo D, Gonzalez-Nilo F, Chipot C. (2012) Insight into the properties of cardiolipin containing bilayers from molecular dynamics simulations, using a hybrid all-atom/united-atom force field. Journal of Chemical Theory and Computation. 8(5):1765-1773.
  • Ardiles AO, Tapia-Rojas CC, Mandal M, Alexandre F, Kirkwood A, Inestrosa NC & Palacios AG. (2012) Post-synaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease. Proceedings of the National Academy of Science. 109(34):13835-40 . Featured in: Pour la Science, Alzheimer Research Forum. PDF
  • Avila-Salas F, Sandoval C, Caballero J, Guinez-Molinos S, Santos, LS, Cachau RE, Gonzalez-Nilo FD. (2012) Study of interaction energies between the PAMAM dendrimer and nonsteroidal anti-inflammatory drug using a distributed computational strategy and experimental analysis by ESI-MS/MS. Journal of Physical Chemistry B. 116 (7):2031-2039. PDF.
  • Bazáes A. and Schmachtenberg O. (2012) Odorant tuning of olfactory crypt cells from juvenile and adult rainbow trout. Journal of Experimental Biology. 215(Pt 10):1740-8. PDF
  • Bennett MV, Garré JM, Orellana JA, Bukauskas FF, Nedergaard M, Sáez JC. (2012) Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Research. 1487:3-15.
  • Braidy N, Munoz P, Palacios AG, Castellano-González G, Inestrosa NC, Chung RS, Sachdev P, Guillemin GJ. (2012) Recent animal models for Alzheimer’s diseases: Clinical implications and basic research. Journal Neural Transmission. 119(2):173-195.
  • Cárdenas AM, Ardiles AO, Barraza N, Baéz-Matus X, Caviedes P. (2012) Role of Tau Protein in Neuronal Damage in Alzheimer’s Disease and Down Syndrome. Archives of Medical Research. 43(8):645-54.
  • Cea LA, Riquelme MA, Cisterna BA, Puebla C, Vega JL, Rovegno M, Sáez JC. (2012) Connexin- and annexin-based channels in normal skeletal muscles and their possible role in muscle atrophy. Journal of Membrane Biology. 245(8):423-36.
  • Contreras GF, Neely A, Alvarez O, Gonzalez C, Latorre R. (2012) Modulation of BK channel voltage gating by different auxiliary β subunits. Proceedings of the National Academy of Sciences. 109(46):18991-18996.
  • Cortés C, Eugenin E, Aliaga E, Carreño LJ, Bueno SM, Gonzalez PA, Gayol S, Naranjo D, Noches V, Marassi MP, Rosenthal D, Jadue C, Ibarra P, Keitel C, Wohllk N, Court F, Kalergis AM, Riedel CA. (2012) Hypothyroidism in the adult rat causes incremental changes in brain-derived neurotrophic factor, neuronal and astrocyte apoptosis, gliosis, and deterioration of postsynaptic density. Thyroid. 22(9):951-63.
  • Couve, E., Osorio, O. and Schmachtenberg, O. (2012) Mitochondrial autophagy and lipofuscin accumulation in aging odontoblasts. Journal of Dental Research. 91(7): 1-6.
  • Dinardo MM, Camerino G, Mele A, Latorre R., Conte Camerino D, Tricarico D. (2012) Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle. Plos One, 7(7):e40235. PDF
  • Eugenin EA, Basilio D, Sáez JC, Orellana JA, Raine CS, Bukauskas F, Bennett MV, Berman JW. (2012) The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. Journal of Neuroimmune Pharmacology. 7(3):499-518.
  • Fiori MC, Figueroa V, Zoghbi ME, Saez JC, Reuss L, Altenberg GA.(2012) Permeation of calcium through purified connexin 26 hemichannels. Journal of Biological Chemistry. 87(48): 40826-34
  • Giaume C, Orellana JA, Abudara V, Sáez JC. (2012) Connexin-based channels in astrocytes: how to study their properties. Methods in Molecular Biology. 814:283-303.
  • Gonzalez C, Báez-Nieto D, Valencia I, Oyarzún I, Rojas P, Naranjo D, and Latorre, R. (2012) K channels: function-structural overview. Comprehensive Physiology. 2: 2087-2149.
  • Gonzalez C, Contreras G, Peysler A, Larsson P, Neely A, Latorre R. (2012) Voltage sensor of ion channels and enzymes. Biophysical Reviews. 4(1): 1-15.
  • Gonzalez W, Riedelsberger J, Morales-Navarro SE, Caballero J, Alzate-Morales JH, González-Nilo FD, Dreyer I. (2012) The ph-sensor of the plant K+ uptake channel Kat1 is built of a sensory cloud rather than of single key amino acids. Biochemical Journal. 442(1):57-63. PDF.
  • Harden MV, Pereiro L, Ramialison M, Wittbrodt J, Prasad MK, McCallion AS, Whitlock KE. (2012) Close association of olfactory placode precursors and cranial neural crest cells does not predestine cell mixing. Developmental Dynamics. 241(7):1143-54.
  • Huang S, Treviño M, He K, Ardiles A, Di Pasquale R, Guo Y, Palacios A, Huganir R, Kirkwood A. (2012) Pull-push neuromodulation of ltp and ltd enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron. 73(3):497-510. PDF
  • Jara O, Acuña R, García IE, Maripillán J, Figueroa V, Sáez JC, Araya-Secchi R, Lagos CF, Pérez-Acle T, Berthoud VM, Beyer EC, Martínez AD. (2012) Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function. Molecular Biology of the Cell. 23(17):3299-3311. PDF
  • Koulakoff A, Mei X, Orellana JA, Sáez JC, Giaume C. (2012) Glial connexin expression and function in the context of Alzheimer’s disease. Biochimica et Biophysica Acta. 1818(8):2048-2057.
  • Lagos CF, Araya-Secchi R, Thomas P, Pérez-Acle T, Tapia RA, Salas CO. (2012) Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione. Journal of Molecular Modeling. 18(5):2055-64.
  • Lahr EC, Dean D, Ewer J. (2012) Genetic analysis of ecdysis behavior in Drosophila reveals partially overlapping functions of two unrelated neuropeptides. Journal of Neuroscience. 32(20):6819-29. PDF
  • Maojo V, Fritts M, Martin-Sanchez F, De la Iglesia D, Cachau RE, Garcia-Remesal M, Crespo J, Mitchell JA, Anguita A, Baker N, Barreiro JM, Benitez SE, De la Calle G, Facelli JC, Ghazal P, Geissbuhler A, Gonzalez-Nilo F, Graf N, Grangeat P, Hermosilla I, Hussein R, Kern J, Koch S, Legre Y, Lopez-Alonso V, Lopez-Campos G, Milanesi L, Moustakis V, Munteanu C, Otero P, Pazos A, Perez-Rey D, Potamias G, Sanz F, Kulikowski C. (2012) Nanoinformatics: developing new computing applications for nanomedicine. Comput Sci Eng. 94(6):521-539.
  • Miranda-Laferte E, Schmidt S, Jara AC, Neely A, Hidalgo P. (2012) A short polybasic segment between the two conserved domains of the β2a-subunit modulates the rate of inactivation of R-type calcium channel. The Journal of Biological Chemistry. 287(39):32588-97. PDF
  • Morera FJ, Alioua A, Kundu P, Salazar M, Gonzalez C, Martinez AD, Stefani E, Toro L, Latorre R. (2012). The first transmembrane domain (TM1) of β2-subunit binds to the transmembrane domain S1 of α-subunit in BK potassium channels. FEBS Letters. 586(16):2287-93.
  • Moscoso C, Vergara-Jaque A, Márquez-Miranda V, Sepúlveda R, Valencia I, Díaz-Franulic I, González-Nilo F, Naranjo D. (2012) K+ Conduction and Mg2+ Blockade in a Shaker Kv-Channel Single Point Mutant with an Unusually High Conductance. Biophysical Journal, 103(6):1198-1207.
  • Muñoz P and Humeres A. (2012) Iron deficiency on neuronal function. Biometals 25:825–835.
  • Muñoz P (2012) Iron-mediated redox modulation in neural plasticity. Communicative & Integrative Biology 5:2,166–168. PDF
  • Nunez F, Ravello C, Urbina H, Perez-Acle T. (2012) A Rule-based Model of a Hypothetical Zombie Outbreak: Insights on the role of emotional factors during behavioral adaptation of an artificial population. arXiv:1210.4469v1 [q-bio.PE]
  • Orellana JA, Sáez PJ, Cortés-Campos C, Elizondo RJ, Shoji KF, Contreras-Duarte S, Figueroa V, Velarde V, Jiang JX, Nualart F, Sáez JC, García MA. (2012) Glucose increases intracellular free Ca(2+) in tanycytes via ATP released through connexin 43 hemichannels. Glia. 60(1):53-68. PDF
  • Orellana JA, Sánchez HA, Schalper KA, Figueroa V, Sáez JC. (2012) Regulation of intercellular calcium signaling through calcium interactions with connexin-based channels. Advances in Experimental Medicine and Biology.740:777-794.
  • Orellana JA, von Bernhardi R, Giaume C, and Sáez JC. (2012) Glial hemichannels and their involvement in neurodegenerative diaseases. Reviews in Neuroscience. 23(2): 163–177.
  • Orio P, Parra A, Madrid R, González O, Belmonte C, Viana F. (2012) Role of ih in the firing pattern of mammalian cold thermoreceptor endings. J Neurophysiol. 108(11):3009-23.
  • Orio P, Soudry D. (2012) Simple, fast and accurate implementation of the diffusion approximation algorithm for stochastic ion channels with multiple states. PLoS ONE. 7(5): e36670. PDF
  • Perez-Armendariz EM, Cruz-Miguel L, Coronel-Cruz C, Esparza-Aguilar M, Pinzon-Estrada E, Rancano-Camacho E, Zacarias-Climaco G, Olivares PF, Espinosa AM, Becke, I, Saez JC, Berumen J, Perez-Palacios G. (2012) Connexin 36 is expressed in beta and connexins 26 and 32 in acinar cells at the end of the secondary transition of mouse pancreatic development and increase during fetal and perinatal life. Anatomical Record-Advances In Integrative Anatomy And Evolutionary Biology. 295(6): 980-990 .
  • Pertusa M, Moldenhauer H, Brauchi S, Latorre R, Madrid R, Orio P (2012). Mutagenesis and temperature-sensitive little machines. In: Mutagenesis, Mishra, R. Ed., InTech Open Access publisher. Chapter 11, pp 221-246.
  • Rovegno M, Soto PA, Sáez JC, von Bernhardi R. (2012) Biological mechanisms involved in the spread of traumatic brain damage. Med Intensiva. 36(1):37-44. PDF
  • Schalper KA, Riquelme MA, Brañes MC, Martínez AD, Vega JL, Berthoud VM, Bennett MV, Sáez JC. (2012) Modulation of gap junction channels and hemichannels by growth factors. Molecular BioSystems. 8(3): 685-698.
  • Stehberg J, Moraga-Amaro R, Salazar C, Becerra A, Echeverría C, Orellana JA, Bultynck G, Ponsaerts R, Leybaert L, Simon F, Sáez JC, Retamal MA. (2012) Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala. FASEB Journal. 26(9):3649-57
  • Stephenson JF, Partridge JC, Whitlock KE. (2012) Food and conspecific chemical cues modify visual behavior of zebrafish, danio rerio. Zebrafish. 9:68-73.
  • Sundram V, Fanny S, Ng FS, Roberts MA, Millán C, Ewer J, Jackson FR. (2012) Requirements for LARK in the Drosophila circadian system. Journal of Biological Rhythms. 27(3):183-95.
  • Vasquez JC, Palacios AG, Marre O, Berry II MJ, Cessac B (2012). Gibbs distribution analysis of temporal correlation structure on multicell spike trains from retina ganglions cells. Journal of Physiology Paris. 106(3-4):120-7 .
  • Vergara-Jaque A, Poblete H, Lee EH, Schulten K, Gonzalez-Nilo FD, Chipot CJ. (2012) Molecular basis of drug resistance in A/H1N1 virus. Journal of Chemical Information and Modeling. 52(10):2650-6
  • Vielma AH, Retamal M, Schmachtenberg O. (2012) Nitric oxide signaling in the retina: What have we learned in two decades?. Brain Research. 430:112-25.

2011

  • Baez-Nieto D, Castillo JP, Dragicevic C, Alvarez O, Latorre R. (2011) Thermo-TRP channels: biophysics of polymodal receptors. Advances in Experimental Medicine and Biology. 704:469-490.
  • Brauchi S, Orio P. (2011) Voltage sensing in thermo-TRP channels. Advances in Experimental Medicine and Biology. 704:517-530.
  • Castillo JP, De Giorgis D, Basilio D, Gadsby DC, Rosenthal JJ, Latorre R, Holmgren M, Bezanilla F. (2011) Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. Proceedings of the National Academy of Sciences. 108:20556-20561. PDF
  • Couve E, Schmachtenberg O. (2011) Autophagic activity and aging in human odontoblasts. Journal of Dental Research. 90(4): 523-8.
  • Delgado LM, Schmachtenberg O. (2011) Neurogenesis in the adult goldfish cerebellum. The Anatomical Record 294(1): 11-15. PDF
  • González A, Perez-Acle T, Pardo L, Deupi X. (2011) Molecular basis of ligand dissociation in b-adrenergic receptors. PLoS One. 6(9): e23815. PDF
  • Gonzalez C, Lopez Rogriguez A, Srikumar D, Rosenthal J,Holmgren M (2011) Editing of human KV1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. Nature Communications. 2:436. PDF
  • Gonzalez C*, Manzanares D*, Ivonnet P, Chen RS, Valencia-Gattas M, Conner G.E, Larsson HP, Salathe M *Contributed equally. (2011) Functional apical BK channels are required for maintenance of airway surface liquid volume. The Journal of Biological Chemistry. 286(22):19830-9. PDF
  • Grbić M, Van Leeuwen T, Clark RM, Rombauts S, Rouzé P, Grbić V, Osborne EJ, Dermauw W, Ngoc PC, Ortego F, Hernández-Crespo P, Diaz I, Martinez M, Navajas M, Sucena É, Magalhães S, Nagy L, Pace RM, Djuranović S, Smagghe G, Iga M, Christiaens O, Veenstra JA, Ewer J, Mancilla R, Villalobos RM, Hutter JL, Hudson SD, Velez M, Yi SV, Zeng J, Pires-daSilva A, Roch F, Cazaux M, Navarro M, Zhurov V, Acevedo G, Bjelica A, Fawcett JA, Bonnet E, Martens C, Baele G, Wissler L, Sanchez-Rodriguez A, Tirry L, Blais C, Demeestere K, Henz SR, Gregory TR, Mathieu J, Verdon L, Farinelli L, Schmutz J, Lindquist E, Feyereisen R, Van de Peer Y. (2011) The genome of Tetranychus urticae reveals herbivorous pest adaptations. Nature. 479(7374):487-92.
  • Latorre R, Brauchi S, Madrid R, Orio P. (2011) A cool channel in cold transduction. Physiology (Bethesda). 26(4):273-85. PDF
  • Martínez AD, Maripillán J, Acuña R, Minogue PJ, Berthoud VM, Beyer EC (2011) Different domains are critical for oligomerization compatibility of different connexins. Biochemical Journal 436(1):35-43. PDF
  • Miranda-Laferte E, Gonzalez-Gutierrez G, Schmidt S , Zeug A, Ponimaskin EG, Neely A, Hidalgo P. (2011) Homodimerization of the Src homology 3 domain of the calcium channel beta-subunit drives dynamin-dependent endocytosis. Journal of Biological Chemistry. 286(25): 22203-10.
  • Muñoz P, Humeres A, Elgueta C, Kirkwood A, Hidalgo C, Núñez MT. (2011) Iron mediates N-methyl-D-aspartate receptor-dependent stimulation of calcium-induced pathways and hippocampal synaptic plasticity. Journal of Biological Chemistry. 286(15): 13382-92. PDF
  • Palacios AG, Cosmelli D, Cohen-Varela A. (2011) Un recorrido junto a Francisco Varela. Pag. 11-22. Edit. Adrian Palacios y Amy Cohen-Varela. La ciencia del ser: Las rutas de Francisco Varela. Editorial Universidad de Valparaiso. 320 p.
  • Paul TA, Rovnak J, Quackenbush SL, Whitlock KE, Zhan H, Gong Z, Spitsbergen J, Paul R, Bowser PR, Casey JW. (2010). Transgenic expression of Walleye Dermal Sarcoma accessory genes in zebrafish does not result in tissue proliferation. Marine Biotechnology (NY). 13(2):142-50. PDF
  • Orellana JA, Giaume C, Sáez JC. (2011) Role of Connexin Hemichannels in Neurodegeneration. Neurodegenerative diseases – processes, prevention, protection and monitoring Edited by: Raymond Chuen-Chung Chang ISBN 978-953-307-485-6 Publisher: InTech 10:235-254.
  • Orellana JA, Shoji KF, Abudara V, Ezan P, Amigou E, Sáez PJ, Jiang JX, Naus CC, Sáez JC, Giaume C. (2011) Amyloid β-induced death in neurons involves glial and neuronal hemichannels. The Journal of Neuroscience. 31(13):4962-77. PDF
  • Orellana JA, Froger N, Ezan P, Jiang JX, Bennett MV, Naus CC, Giaume C, Sáez JC. (2011) ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels. Journal of Neurochemistry. 118(5):826-40.
  • Orellana JA, Figueroa XF, Sanchez HA, Contreras-Duarte S, Velarde V, Saez JC. (2011) Hemichannels in the neurovascular unit and white matter under normal and inflamed conditions. CNS & Neurological Disorders – Drug Targets. 10(3): 404-14.
  • Salazar M, Moldenhauer H, Baez-Nieto D. (2011) Could an allosteric gating model explain the role of TRPA1 in cold hypersensitivity?. (Journal Club) The Journal of Neuroscience. 31(15):5554-56. PDF
  • Stephenson JF, Whitlock KE, Partridge JC. (2011) Zebrafish preference for light or dark is dependent on ambient light levels and olfactory stimulation. Zebrafish. 8(1): 17-22.

2010

  • Cárdenas AM, Marengo FD. (2010) Rapid endocytosis and vesicle recycling in neuroendocrine cells. Cellular and Molecular Neurobiology. 30(8):1365-70
  • Delgado LM, Couve E, Schmachtenberg O. (2010) GABA and glutamate immunoreactivity in tentacles of the sea anemone Phymactis papillosa (Lesson 1830). Journal of Morphology. 271(7): 845-52.
  • Gonzalez C and Larsson HP. (2010) Permeation mechanism in voltage-activated proton channels: A new glimpse. Proceedings of the National Academy of Science. 107(5):1817-8.
  • González-Gutiérrez G, Miranda-Laferte E, Contreras G, Neely A. & Hidalgo P. (2010) Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 high-voltage gated calcium channels exchanges activation attributes. Channels 4(1):42-50.
  • Gonzalez-Jamett AM, Báez-Matus X, Hevia MA, Guerra MJ, Olivares MJ, Martínez AD, Neely A, Cárdenas AM (2010) The association of dynamin with synaptophysin regulates quantal size and duration of exocytotic events in chromaffin cells. Journal of Neuroscience. 30(32):10683-10691.
  • González-Pérez V, Stack K, Boric K, Naranjo D. (2010) Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling. Proceedings of the National Academy of Science. 107(11):5178-83.
  • Latorre R, Morera FJ, Zaelzer C. (2010). Voltage-Dependent K+ Channels. In Enciclopedia of Biological Chemistry, 2nd edition. Edited by William Lennarz and M. Daniel Lane. Academia Press, Elsevier, NY.
  • Latorre R, Morera F, Zaelzer C. (2010) Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel. The Journal of Physiology. 588(17): 3141–8. PDF
  • Martinez-Harms J, Palacios AG, Marquez IN, Arroyo MTK, Mpdozis J (2010) Can red floweers be conspicuous to bees? Bombus dahbomii and South American temperate forests flowers as a case in point. Journal Experimental Biology 213(4): 564-71.
  • Muñoz PC, Aspé M, Contreras L, Palacios AG, (2010) Correlations of recognition memory performance with expression and methylation of brain-derived neurotrophic factor in rats. Biological Research. 43(2):251-8.
  • Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. (2011) KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate. Proceedings of the National Academy of Science. 107(52):22710-5.
  • Palacios AG, Bozinovic F, Vielma A, Arrese CA, David M. Hunt DM, Peichl L. (2010) Retinal photoreceptor arrangement, SWS and LWS opsin sequence, and electroretinography in the South American marsupial Thylamys elegans (Waterhouse, 1839). The Journal of Comparative Neurology. 518(9):1589-1602.
  • Schleich C, Vielma A, Glosmann M, Palacios AG, Peichl L (2010) The retinal Photoreceptors of Two Subterranean Tuco-tico Species (Rodentia, Ctenomys): Morphology, Topography and Spectral Sensitivity. The Journal of Comparative Neurology. 518(19);4001-4015.
  • Cessac B, Vasquez JC, Nasser H, Rostro-González H, Vieville T, Palacios AG (2010). Parametric estimation of spike train statistic by Gibbs distribution: An application to bio-inspirared and experimental data. NEUROCOMP 2010 Accepted paper for oral presentation.
  • Vielma A, Delgado LM, Osorio R, Elgueta C, Palacios AG, Schmachtenberg O. (2010) Nitric oxide amplifies the rat electroretinogram. Experimental Eye Research. 91(5):700-709.

2009

  • Curé M, Palacios AG (2009) Do Hummingbird see in the Ultraviolet? The Open Medical Informatics Journal. 3:9-12.
  • Delgado L, Vielma A, Kähne T, Palacios AG, and Schmachtenberg O. (2009) The GABAergic system in the retina of neonate and adult Octodon degus, studied by immunohistochemistry and electroretinography. The Journal of Comparative Neurology. 514 (5):459-72.
  • Gonzalez C, Koch HP, Drum B, Larsson HP. (2009) Strong cooperativity between subunits involtage-gated proton channels. Nature Structural & Molecular Biology. 17(1):51-6.
  • Hammami S, Willumsen NJ, Olsen HL, Morera FJ, Latorre R, Klaerke DA. (2009) Cell volume and membrane stretch independently control K+ channel activity. The Journal of Physiology. 587(10):2225-31.
  • Latorre R. (2009) Perspectives on TRP channel structure and the TRPA1 puzzle. The Journal of General Physiology. 133(3):227-9.
  • Latorre R, Zaelzer C, Brauchi S. (2009) Structure and functional intimacies of transient receptor potential (TRP) channels. Quarterly Reviews of Biophysics. 42(3):201-46.
  • Martinez AD, Acuña R, Figueroa V, Maripillan J, Nicholson (2009) Gap Junction Channels dysfunction in deafness and hearing loss. Antioxidants and Redox Signaling. 11(2): 309-22.
  • Orio P, Madrid R, de la Peña E, Parra A, Meseguer V, Bayliss DA, Belmonte C, Viana F (2009) Characteristics and physiological role of hyperpolarization activated currents in mouse cold thermoreceptors. The Journal of Physiology. 587(Pt 9):1961-76.
  • Palacios AG. (2009) La red encarnada: cerebro vs metrópolis (Chapter). Editorial Ariel, España.
  • Paré AC, Dean DM, Ewer J. (2009) Construction and characterization of deletions with defined endpoints in drosophila using P-elements in Trans. Genetics. 181 (1) 53:63.
  • Zagal JC, Delpiano J. Ruiz del Solar J. (2009) Self-modeling in humanoid soccer robots, robotics and autonomous systems, 57(8):819–827.

2008

  • Carvacho I, Gonzalez W, Torres Y, Brauchi S, Alvarez O, Gonzalez-Nilo FD, Latorre R. (2008). Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block. Journal of General Physiology. 31:147-162.
  • Delgado LM, Schmachtenberg O. (2008) Immunohistochemical localization of GABA, GAD65 and the receptor subunits GABAAα1 and GABAB1 in the zebrafish cerebellum. Cerebellum. 7(3):444-50.
  • González-Gutiérrez G, Miranda-Laferte E, Naranjo D, Hidalgo P, Neely A (2008) Mutations of non-conserved residues within the calcium channel alpaha1;-interaction domain inhibit beta-subunit potentiation. The Journal of General Physiology. 132(3):383-95.
  • Gonzalez-Gutierrez G, Miranda-Laferte E, Nothmann D, Schmidt S, Neely A, Hidalgo P. (2008) The guanylate kinase domain of the b-subunit of voltage- gated calcium channels suffices to modulate gating. Proceeding National Academy of Science USA. 105(37):14198-203.
  • González-Pérez V, Neely A, Tapia C, González-Gutiérrez G, Contreras G, Orio P, Lagos V, Rojas G, Estévez T, Stack K, Naranjo D. (2008) Slow inactivation in Shaker K channels is delayed by intracellular tetraethylammonium. The Journal of General Physiology. 132(6):633-50.
  • Herrera G, Zagal JC, Diaz M, Fernández MJ, Vielma A, Cure M, Martinez J, Bozinovic F, Palacios AG. (2008) Spectral sensitivities of photoreceptors and their role in colour discrimination in the Green-backed Firecrown Hummingbird (Sephanoides sephaniodes). Journal of Comparative Physiology A Neuroethology, Sensory, Neural, and Behavioral Physiology. 194(9):785-94.
  • Honegger HW, Dewey EM, Ewer J. (2008) Bursicon, the tanning hormone of insects: recent advances following the discovery of its molecular identity. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 194(12):989-1005.
  • Opazo MC, Gianini A, Pancetti F, Azkcona G, Alarcón L, Lizana R, Noches V, Gonzalez PA, Porto M, Mora S, Rosenthal D, Eugenin E,Naranjo D, Kalergis AM, Riedel CA. (2008) Maternal hypothyroxinemia impairs spatial learning and synaptic nature and function in the offspring. Endocrinology. 149(10):5097-106.
  • Paula-Lima A, Arriagada C, Toro R, Cárdenas AM, Caviedes R, Ferreira ST, Caviedes P, (2008). Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line. Biological Research. 41: 129-136.
  • Rojas G, Cárdenas AM, Fernández-Olivares P, Shimahara T, Segura-Aguilar J, Caviedes R, Caviedes P. (2008). Effect of the knockdown of amyloid precursor protein on intracellular calcium increases in a neuronal cell line derived from the cerebral cortex of a trisomy 16 mouse. Experimental Neurology. 209(1):234-42.
  • Schalper K, Palacios-Prado N, Retamal M, Shoji K, Martínez AD, Sáez JC (2008) Connexin hemichannel composition determines the FGF-1-induced membrane permeability and free [Ca2+]i responses. Molecular Biology of the Cell. 19: 3501-3513.
  • Vielma A, Ardiles A, Delgado LM, Schmachtenberg O. (2008) The elusive crypt olfactory receptor neuron: Evidence for its stimulation by amino acids and cAMP pathway agonists. The Journal of Experimental Biology. 211(15):2417-22.
  • Whitlock KE. (2008) Developing a sense of scents: plasticity in olfactory placode formation. Brain Research Bulletin. 75(2-4):340-7.
  • Zagal JC, Ruiz-del-Sola, J, Palacios AG. (2008). Fitness based identification of a robot structure. Proc. 11th Int. Conf. on Artificial Life, pp.733-740, MIT Press, Cambridge, MA. Full Paper Accepted with Oral presentation.http://www.alifexi.org/papers/ALIFExi_pp733-740.pdf

2007

  • Ardiles A, González-Jamett AM, Maripillan J, Naranjo D, Caviedes P, Cárdenas AM (2007). Calcium channel subtypes differentially regulate fusion pore stability and expansion. Journal of Neurochemistry. 103:1574-81.
  • Brauchi S, Orta G, Mascayano C, Salazar M, Raddatz N, Urbina H,Rosenman E, Gonzalez-Nilo F, Latorre R. (2007). Dissection of the components for PIP2 activation and thermosensation in trp channels. Proceedings of the National Academy of Sciences 104:10246-51.
  • Cosmelli D, Palacios AG. (2007) Networks in cognitive systems and biomedicine: cerebral processes, models and mathematical tools design. Biological Research. 40(4):381-4.
  • Ewer J. (2007) The Neuroendocrinology of eclosion. Chapter in: Invertebrate Neurobiology, Greenspan, R., and North, G., Eds. Cold Spring Harbor Press. P 555-579. Book Chapter.
  • Flanagan CA, Chen CC, Coetsee M, Mamputha S, Whitlock KE, Bredenkamp N, Grosenick L, Fernald RD, Illing N.(2007). Expression, structure, function, and evolution of gonadotropin-releasing hormone (GnRH) receptors GnRH-R1SHS and GnRH-R2PEY in the teleost, Astatotilapia burtoni. Endocrinology 10:5060-71.
  • Goles E, Palacios AG. (2007) Dynamical complexity in cognitive neural networks. Biological Research. 40(4):479-85.
  • Gonzalez-Gutierrez G, Miranda-Laferte E, Neely A, Hidalgo P. (2007) The Src homology 3 domain of the β-subunit of voltage-gated calcium channels promotes endocytosis via dynamin interaction. The Journal of Biological Chemistry. 282: 2156-62.
  • Hidalgo P. and Neely A. (2007). Multiplicity of protein interactions and functions of the voltage-gated calcium channel β-subunit. Cell Calcium. 42:389-96.
  • Latorre, R., Brauchi, S., Orta, G., Zaelzer, C., Vargas, G. (2007). ThermoTRP channels as modular proteins with allosteric gating. Cell Calcium. 42:427-38.
  • Lin DM, Loveall B, Ewer J, Deitcher DL, Sucher NJ. (2007) Characterization of mRNA expression in single neurons. Methods in Molecular Biology. 399:133-52. Review.
  • Morera F, Vargas G, González C, Rossenman E, Latorre R. (2007) Ion channel reconstitution. In: Protocols in Biophysics to Study membrane Lipids. Dopico, A. Ed. Humana Press, NJ. 400:571-85.
  • Schmachtenberg, O. (2007) Epithelial sentinels or protozoan parasites? Studies on isolated rodlet cells on the 100th Anniversary of an enigma. Revista Chilena de Historia Natural. 80: 55-62.
  • Torres Y, Morera FJ, Carvacho I, Latorre R. (2007). A marriage of convenience: beta-subunits of voltage-dependent K+ channels. The Journal of Biological Chemistry. 282(34):24485-9. Review

2006

  • Ardiles AO, Maripillan J, Lagos V, Toro R., Mora IG, Villarroel L, Ales E, Borges R, Cardenas AM, (2006). A rapid exocytosis mode in chromaffin cells with a neuronal phenotype. Journal of Neurochemistry 99:29-41.
  • Brauchi S, Orta G, Salazar M, Rosenmann E, Latorre R. (2006). A hot-sensing cold-receptor: C-terminal domain determines thermosensation in TRP channels. The Journal of Neuroscience. 26:4835-40.
  • Bruckner G, Pavlica S, Morawski M, Palacios AG, Reichenbach A. (2006). Organization of brain extracellular matrix in the Chilean fat-tailed mouse opossum Thylamys elegans (Waterhouse, 1839). Journal of Chemical Neuroanatomy 32:143-158.
  • DePuy SD, Junlan Y, Hu Ch, McIntire W, Bidaud I, Lory P, Rastinejad F, Gonzalez C, Garrison JC, and Barrett PQ. The molecular basis for T-type Ca2+ channel inhibition by G-protein β2γ2 subunits. Proc. Natl. Acad. Sci. USA. 103: 14590-5.
  • Ewer J. (2006) Behavioral endocrinology: Lighting up peptidergic neurons that mediate a complex behavior. Current Biology 16:R682-R684.
  • Harden MV, Newton LA, Lloyd RC, Whitlock KE. (2006) Olfactory imprinting is correlated with changes in gene expression in the olfactory epithelia of the zebrafish. Journal of Neurobiology 66:1452-1466.
  • Hardstone MC, Baker SA, Gao JW, Ewer J, Scott JG. (2006) Deletion of Cyp6d4 does not alter toxicity of insecticides to Drosophila melanogaster. Pesticide Biochemistry and Physiology 84:236-242.
  • Hidalgo P, Gonzalez-Gutierrez G, Garcia-Olivares J, Neely A. (2006) The alpha(1)-beta-subunit interaction that modulates calcium channel activity is reversible and requires a competent alpha-interaction domain. Journal of Biological Chemistry 281:24104-10.
  • Latorre R and Brauchi S. (2006). Large conductance Ca2+-activated K+ (BK) channels: activation by Ca2+ and voltage. Bioogical Research. 39:385-401
  • Latorre R, Vargas G, Orta G, Brauchi S. (2006) Voltage and temperature gating in thermoTRP channels. In: TRP Ion Channels Function in Sensory Transduction and Cellular Signaling Cascades. Liedtke, W. and Heller, S. Eds. CRC Taylor and Francis, London. Chapter 21, pp 287.302.
  • Ocampo-Garces A, Mena W, Hernandez F, Cortes N, Palacios AG. (2006) Circadian chronotypes among wild-captured west Andean octodontids. Biological Research. 39:209-220.
  • Opazo P, Saud K, Saint Pierre M, Cardenas AM, Allen DD, Segura-Aguilar J, Caviedes R, Caviedes P. (2006) Knockdown of amyloid precursor protein normalizes cholinergic function in a cell line derived from the cerebral cortex of a trisomy 16 mouse: An animal model of Down syndrome. Journal of Neuroscience Research. 84:1303-1310.
  • Orio P, Torres Y, Rojas P, Carvacho I, Garcia ML, Toro L, Valverde MA, Latorre R. (2006). Structural determinants for functional coupling between the β and α subunits in the Ca2+-activated K+ (BK) Channel. The Journal of General Physiology. 127:191-204.
  • Saud K, Arriagada C, Cardenas AM, Shimahara T, Allen DD, Caviedes R, Caviedes P. (2006). Neuronal dysfunction in Down syndrome: Contribution of neuronal models in cell culture. Journal of Physiology-Paris 99:201-210.
  • Schmachtenberg O. (2006) Histological and electrophysiological properties of crypt cells from the olfactory epithelium of the marine Teleost Trachurus symmetricus. The Journal of Comparative Neurology. 495(1): 113-121.
  • Whitlock KE, Illing N, Brideau NJ, Smith KM, Twomey S. (2006). Development of GnRH cells: Setting the stage for puberty. Molecular and Cellular Endocrinology 254:39-50.
  • Whitlock KE. (2006) The sense of scents: olfactory behaviors in the zebrafish. Zebrafish. 2006;3(2):203-13.

2005

  • AllenDD, Caviedes R, Cardenas AM, Shimahara T, Segura-Aguilar J, Caviedes PA. (2005) Cell lines as in vitro models for drug screening and toxicity studies. Drug Development and Industrial Pharmacy 31:757-768.
  • Alvarez O, Rosenmann E, Bezanilla F, González C, Latorre R. (2005) Helical nature of the voltage sensor. In: Pumps, transporters and ion channels. Studies on their structure, function and cell biology. Sepúlveda F, Bezanilla F, Eds. Plenum Press, NY. Pp. 93-101.
  • Dulcis D, Levine RB, Ewer J. (2005). Role of the neuropeptide CCAP in Drosophila cardiac function. Journal of Neurobiology 64:259-274.
  • Ewer J. (2005). Behavioral actions of neuropeptides in invertebrates: Insights from Drosophila. Hormones and Behavior 48:418-429.
  • Ewer J. (2005). How the ecdysozoan changed its coat. Plos Biology 3:1696-1699.
  • González C, Morera F, Rosenmann E, Alvarez O, Latorre R, (2005) S3b amino acid residues do not shuttle across the bilayer in voltage-dependent Shaker K+ channels. Proceedings of the National Academy of Science. 102:5020-5025.
  • Luo CW, Dewey EM, Sudo S, Ewer J, Hsu SY, Honegger HW, Hsueh AJW. (2005) Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proceedings of the National Academy of Sciences of the United States of America 102:2820-2825.
  • Melendez J, Galli I, Boric K, Ortega A, Zuniga L, Henriquez-Roldan CF, Cardenas AM. (2005). Zolpidem and triazolam do not affect the nocturnal sleep-induced memory improvement. Psychopharmacology 181:21-26.
  • Naranjo D, Oliva, Gonzalez CV, Neely A. (2005) Two slow inactivation processes in Shaker-IR potassium channels. Biophysical Journal 88:462A.
  • Ocampo-Garces A, Hernandez F, Mena W, Palacios AG. (2005) Wheel-running and rest activity pattern interaction in two octodontids (Octodon degus, Octodon bridgesi). Biological Research 38:299-305.
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